Pocketome is an encyclopedia of conformational ensembles of all druggable binding sites that can be identified experimentally from co-crystal structures in the Protein Data Bank. Each Pocketome entry corresponds to a small molecule binding site in a protein which has been co-crystallized in complex with at least one drug-like small molecule, and is represented in at least two PDB entries.

Prefix

pocketome

Keywords

life science

Links

Homepage

Contact

Ruben Abagyan   0000-0001-9309-2976

Pattern for Local Unique Identifiers

Local identifiers in Pocketome should match this regular expression:
^[A-Za-z_0-9]+$

Example Local Unique Identifier

1433C_TOBAC_1_252   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from Pocketome should match this regular expression:
^pocketome:[A-Za-z_0-9]+$

Example CURIE

pocketome:1433C_TOBAC_1_252

Publications

• 2011 Pocketome: an encyclopedia of small-molecule binding sites in 4D
• 2009 The flexible pocketome engine for structural chemogenomics

The metaregistry provides mappings between the Bioregistry and other registries. There are 5 mappings to external registries for this resource with 3 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 1433C_TOBAC_1_252 is used to demonstrate the providers available for Pocketome. A guide for curating additional providers can be found here.