Pocketome is an encyclopedia of conformational ensembles of all druggable binding sites that can be identified experimentally from co-crystal structures in the Protein Data Bank. Each Pocketome entry corresponds to a small molecule binding site in a protein which has been co-crystallized in complex with at least one drug-like small molecule, and is represented in at least two PDB entries.

Prefix

pocketome

Keywords

binding site life science polypeptide region protein interactions small molecule structure

Links

Homepage

Publications

2011 Pocketome: an encyclopedia of small-molecule binding sites in 4D

2009 The flexible pocketome engine for structural chemogenomics

Pattern for Local Unique Identifiers

Local identifiers in Pocketome should match this regular expression:
^[A-Za-z_0-9]+$

Example Local Unique Identifier

1433C_TOBAC_1_252   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from Pocketome should match this regular expression:
^pocketome:[A-Za-z_0-9]+$

Example CURIE

pocketome:1433C_TOBAC_1_252

Contact

Ruben Abagyan   0000-0001-9309-2976

Mappings from records in Bioregistry to external registries comprises the metaregistry. This resource has 5 mappings to external registries with 3 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 1433C_TOBAC_1_252 is used to demonstrate the providers available for Pocketome. Some providers may use a different example, which is displayed in the table below. A guide for curating additional providers can be found here.