The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models (CMs). The families in Rfam break down into three broad functional classes: non-coding RNA genes, structured cis-regulatory elements and self-splicing RNAs. Typically these functional RNAs often have a conserved secondary structure which may be better preserved than the RNA sequence. The CMs used to describe each family are a slightly more complicated relative of the profile hidden Markov models (HMMs) used by Pfam. CMs can simultaneously model RNA sequence and the structure in an elegant and accurate fashion.

Prefix

rfam

Links

Homepage

Contact

Missing Contact

Pattern for Local Unique Identifiers

Local identifiers in Rfam database of RNA families should match this regular expression:
^RF\d{5}$

Example Local Unique Identifier

RF00230   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from Rfam database of RNA families should match this regular expression:
^rfam:RF\d{5}$

Example CURIE

rfam:RF00230

The metaregistry provides mappings between the Bioregistry and other registries. There are 7 mappings to external registries for rfam with 3 unique external prefixes.

Providers are various services that resolve CURIEs to URLs. The example CURIE rfam:RF00230 is used to demonstrate the provides available for rfam. Generation of OLS and BioPortal URLs requires additional programmatic logic beyond string formatting.