CIViC variants are usually genomic alterations, including single nucleotide variants (SNVs), insertion/deletion events (indels), copy number alterations (CNV’s such as amplification or deletion), structural variants (SVs such as translocations and inversions), and other events that differ from the “normal” genome. In some cases a CIViC variant may represent events of the transcriptome or proteome. For example, ‘expression’ or ‘over-expression’ is a valid variant. Regardless of the variant, it must have a Predictive, Prognostic, Predisposing, Diagnostic, Oncogenic, or Functional relevance that is clinical in nature to be entered in CIViC. i.e. There must be some rationale for why curation of this variant could ultimately aid clinical decision making.

Missing Contact
Pattern for Local Unique Identifiers

Local identifiers in CIViC variant should match this regular expression:

Example Local Unique Identifier
12   Resolve
Pattern for CURIES

Compact URIs (CURIEs) constructed from CIViC variant should match this regular expression:

Example CURIE
Part Of (bfo:0000050 )
civic (not directly registered)
In Collection
Global Biodata Coalition - Global Core Biodata Resources
Metaregistry CIViC variant

The metaregistry provides mappings between the Bioregistry and other registries. There are 2 mappings to external registries for this resource with 2 unique external prefixes.

Registry Name Registry Metaprefix External Prefix Curate logo miriam civic.vid
Wikidata Wikidata Property logo wikidata P3329

Providers are various services that resolve CURIEs to URLs. The example CURIE None:12 is used to demonstrate the provides available for this resource. Generation of OLS and BioPortal URLs requires additional programmatic logic beyond string formatting.

Name Metaprefix URI
CIViC variant civic.vid
Bioregistry bioregistry miriam