Evidence Items are the central building block of the Clinical Interpretation of Variants in Cancer (CIViC) knowledgebase. The clinical Evidence Item is a piece of information that has been manually curated from trustable medical literature about a Variant or genomic ‘event’ that has implications in cancer Predisposition, Diagnosis (aka molecular classification), Prognosis, Predictive response to therapy, Oncogenicity or protein Function. For example, an Evidence Item might describe a line of evidence supporting the notion that tumors with a somatic BRAF V600 mutation generally respond well to the drug dabrafenib. A Variant may be a single nucleotide substitution, a small insertion or deletion, an RNA gene fusion, a chromosomal rearrangement, an RNA expression pattern (e.g. over-expression), etc. Each clinical Evidence statement corresponds to a single citable Source (a publication or conference abstract).

Prefix

civic.eid

Alternative Prefixes

civic.evidence

License

CC0-1.0

Links

Homepage

Contact

Malachi Griffith   0000-0002-6388-446X   malachig

Pattern for Local Unique Identifiers

Local identifiers in CIViC Evidence should match this regular expression:
^[0-9]+$

Example Local Unique Identifier

1199   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from CIViC Evidence should match this regular expression:
^civic\.eid:[0-9]+$

Example CURIE

civic.eid:1199

A summary of the relations in the Bioregistry schema can be found here.

Part Of (bfo:0000050 )

civic (not directly registered)

In Collection

Global Biodata Coalition - Global Core Biodata Resources

The metaregistry provides mappings between the Bioregistry and other registries. There are 1 mappings to external registries for this resource with 1 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 1199 is used to demonstrate the providers available for CIViC Evidence. A guide for curating additional providers can be found here.