A CIViC assertion classifies the clinical significance of a variant-disease relationship under recognized guidelines. The CIViC Assertion (AID) summarizes a collection of Evidence Items (EIDs) that covers predictive/therapeutic, diagnostic, prognostic or predisposing clinical information for a variant in a specific cancer context. CIViC currently has two main types of Assertions: those based on variants of primarily somatic origin (predictive/therapeutic, prognostic, and diagnostic) and those based on variants of primarily germline origin (predisposing). When the number and quality of Predictive, Prognostic, Diagnostic or Predisposing Evidence Items (EIDs) in CIViC sufficiently cover what is known for a particular variant and cancer type, then a corresponding assertion be created in CIViC.

Prefix
civic.aid
Links
Homepage
Contact
Missing Contact
Pattern for Local Unique Identifiers

Local identifiers in CIViC Assertion should match this regular expression:
^[0-9]+$

Example Local Unique Identifier
3   Resolve
Pattern for CURIES

Compact URIs (CURIEs) constructed from CIViC Assertion should match this regular expression:
^civic.aid:[0-9]+$

Example CURIE
civic.aid:3
Metaregistry

The metaregistry provides mappings between the Bioregistry and other registries. There are 1 mappings to external registries for civic.aid.

Registry Name Metaprefix External Prefix
Identifiers.org miriam civic.aid
Providers

Providers are various services that resolve CURIEs to URLs. The example CURIE civic.aid:3 is used to demonstrate the provides available for civic.aid. Generation of OLS and BioPortal URLs requires additional programmatic logic beyond string formatting.

Name Metaprefix URI
CIViC Assertion civic.aid https://civicdb.org/links/assertions/3
Bioregistry bioregistry https://bioregistry.io/civic.aid:3
Identifiers.org miriam https://identifiers.org/civic.aid:3