A CIViC assertion classifies the clinical significance of a variant-disease relationship under recognized guidelines. The CIViC Assertion (AID) summarizes a collection of Evidence Items (EIDs) that covers predictive/therapeutic, diagnostic, prognostic or predisposing clinical information for a variant in a specific cancer context. CIViC currently has two main types of Assertions: those based on variants of primarily somatic origin (predictive/therapeutic, prognostic, and diagnostic) and those based on variants of primarily germline origin (predisposing). When the number and quality of Predictive, Prognostic, Diagnostic or Predisposing Evidence Items (EIDs) in CIViC sufficiently cover what is known for a particular variant and cancer type, then a corresponding assertion be created in CIViC.

Alternative Prefixes
Malachi Griffith   0000-0002-6388-446X   malachig
Pattern for Local Unique Identifiers

Local identifiers in CIViC Assertion should match this regular expression:

Example Local Unique Identifier
3   Resolve
Pattern for CURIES

Compact URIs (CURIEs) constructed from CIViC Assertion should match this regular expression:

Example CURIE

A summary of the relations in the Bioregistry schema can be found here.

Part Of (bfo:0000050 )
civic (not directly registered)
In Collection
Global Biodata Coalition - Global Core Biodata Resources
Metaregistry CIViC Assertion

The metaregistry provides mappings between the Bioregistry and other registries. There are 1 mappings to external registries for this resource with 1 unique external prefixes.

Registry Name Registry Metaprefix External Prefix Curate
Identifiers.org Identifiers.org logo miriam civic.aid

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 3 is used to demonstrate the providers available for CIViC Assertion. A guide for curating additional providers can be found here.

Name Metaprefix URI
CIViC Assertion civic.aid https://civicdb.org/links/assertions/3
Bioregistry bioregistry https://bioregistry.io/civic.aid:3
Identifiers.org miriam https://identifiers.org/civic.aid:3