The Pathway Ontology captures information on biological networks, the relationships between netweorks and the alterations or malfunctioning of such networks within a hierarchical structure. The five main branches of the ontology are: classic metabolic pathways, regulatory, signaling, drug, and disease pathwaysfor complex human conditions.

Prefix

pw

Preferred Prefix

PW

Keywords

biological regulation disease drug drug metabolism enzymatic reaction human life science mathematical model molecular entity network model obo ontology pathway pathway model signaling

Version

7.85

License

CC-BY-4.0

Links

Homepage Repository OBO OWL

Contact

G. Thomas Hayman   0000-0002-9553-7227   gthayman

Pattern for Local Unique Identifiers

Local identifiers in Pathway ontology should match this regular expression:
^\d{7}$

Example Local Unique Identifier

0000423   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from Pathway ontology should match this regular expression:
^PW:\d{7}$

Example CURIE

PW:0000423

MIRIAM Namespace Embedded in LUI

The legacy MIRIAM standard for generating CURIEs with this resource annotates the namespaceEmbeddedInLUI as true. This means that you may see local unique identifiers that include a redundant prefix and delimiter (also known as a banana) and therefore look like a CURIE. For Pathway ontology, the banana looks like PW:. Therefore, you may see local unique identifiers for this resource that look like PW:0000423 (instead of the canonical form 0000423) and CURIEs for this resource that look like PW:PW:0000423 (instead of the canonical form PW:0000423). The Bioregistry will automatically strip off the banana when standardizing local unique identifiers and CURIEs.

Publications

• 2014 Disease pathways at the Rat Genome Database Pathway Portal: genes in context-a network approach to understanding the molecular mechanisms of disease
• 2014 The pathway ontology - updates and applications
• 2011 The Rat Genome Database pathway portal

The metaregistry provides mappings between the Bioregistry and other registries. There are 11 mappings to external registries for this resource with 3 unique external prefixes.

When using this resource in RDF, the following URI format should be used:

http://purl.obolibrary.org/obo/PW_$1

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 0000423 is used to demonstrate the providers available for Pathway ontology. A guide for curating additional providers can be found here.

Additional providers curated in the Bioregistry are listed here. These are typically inherited from Identifiers.org or Prefix Commons, and need extra curation.