The Reagent Ontology (ReO) adheres to OBO Foundry principles ( to model the domain of biomedical research reagents, considered broadly to include materials applied “chemically” in scientific techniques to facilitate generation of data and research materials. ReO is a modular ontology that re-uses existing ontologies to facilitate cross-domain interoperability. It consists of reagents and their properties, linking diverse biological and experimental entities to which they are related. ReO supports community use cases by providing a flexible, extensible, and deeply integrated framework that can be adapted and extended with more specific modeling to meet application needs.


From James O.: It was an ontology for "reagents" developed by @Matthew Brush. Since OBI was interested in reagents, Matt developed it in coordination with OBI and had plans to submit it to OBO. I believe that REO was once included in Ontobee, and OBI even started using some REO terms. But REO was never submitted to OBO. I believe it was abandoned.

Homepage Repository OWL
Matthew Brush   0000-0002-1048-5019   mbrush
Pattern for Local Unique Identifiers

Local identifiers in Reagent Ontology should match this regular expression:

Example Local Unique Identifier
0000079   Resolve
Pattern for CURIES

Compact URIs (CURIEs) constructed from Reagent Ontology should match this regular expression:

Example CURIE
Metaregistry Reagent Ontology

The metaregistry provides mappings between the Bioregistry and other registries. There are 1 mappings to external registries for reo with 1 unique external prefixes.

Registry Name Registry Metaprefix External Prefix Curate
OntoBee ontobee REO

Providers are various services that resolve CURIEs to URLs. The example CURIE reo:0000079 is used to demonstrate the provides available for reo. Generation of OLS and BioPortal URLs requires additional programmatic logic beyond string formatting.

Name Metaprefix URI
Reagent Ontology reo
Bioregistry bioregistry