COGs stands for Clusters of Orthologous Genes. The database was initially created in 1997 (Tatusov et al., PMID: 9381173) followed by several updates, most recently in 2014 (Galperin et al., PMID: 25428365). The current update includes complete genomes of 1,187 bacteria and 122 archaea that map into 1,234 genera. The new features include ~250 updated COG annotations with corresponding references and PDB links, where available; new COGs for proteins involved in CRISPR-Cas immunity, sporulation, and photosynthesis, and the lists of COGs grouped by pathways and functional systems.
cog
Local identifiers in Cluster of orthologous genes should match this
regular expression:
^COG\d+$
Compact URIs (CURIEs) constructed from Cluster of orthologous genes should match
this regular expression:
^cog:COG\d+$
The metaregistry provides mappings between the Bioregistry and other registries. There are
4 mappings to external registries for cog
with
3 unique external prefixes.
Registry Name | Registry Metaprefix | External Prefix | Curate |
---|---|---|---|
Biolink Model Registry | biolink |
COG
|
|
FAIRSharing
|
fairsharing |
FAIRsharing.djsbw2
|
|
Gene Ontology Registry | go |
COG_Cluster
|
|
Prefix Commons | prefixcommons |
cog
|
Providers are various services that resolve CURIEs to URLs. The example CURIE
cog:COG0001
is used to demonstrate the provides available for
cog
. Generation of OLS and BioPortal URLs requires additional programmatic
logic beyond string formatting.
Name | Metaprefix | URI |
---|---|---|
Cluster of orthologous genes | cog |
https://www.ncbi.nlm.nih.gov/research/cog/cog/COG0001 |
Bioregistry | bioregistry |
https://bioregistry.io/cog:COG0001 |