COGs stands for Clusters of Orthologous Genes. The database was initially created in 1997 (Tatusov et al., PMID: 9381173) followed by several updates, most recently in 2014 (Galperin et al., PMID: 25428365). The current update includes complete genomes of 1,187 bacteria and 122 archaea that map into 1,234 genera. The new features include ~250 updated COG annotations with corresponding references and PDB links, where available; new COGs for proteins involved in CRISPR-Cas immunity, sporulation, and photosynthesis, and the lists of COGs grouped by pathways and functional systems.

Alternative Prefixes
genome life science protein
Michael Y Galperin   0000-0002-2265-5572
Pattern for Local Unique Identifiers

Local identifiers in Cluster of orthologous genes should match this regular expression:

Example Local Unique Identifier
COG0001   Resolve
Pattern for CURIES

Compact URIs (CURIEs) constructed from Cluster of orthologous genes should match this regular expression:

Example CURIE

A summary of the relations in the Bioregistry schema can be found here.

Has Parts (bfo:0000051 )
cog.category cog.pathway
Metaregistry Cluster of orthologous genes

The metaregistry provides mappings between the Bioregistry and other registries. There are 5 mappings to external registries for this resource with 3 unique external prefixes.

Registry Name Registry Metaprefix External Prefix Curate
Biolink Biolink Model Registry logo biolink COG
FAIRSharing FAIRSharing logo fairsharing FAIRsharing.djsbw2
GO Gene Ontology Registry logo go COG_Cluster logo miriam cog
Prefix Commons Prefix Commons logo prefixcommons cog

Providers are various services that resolve CURIEs to URLs. The example CURIE cog:COG0001 is used to demonstrate the provides available for this resource. Generation of OLS and BioPortal URLs requires additional programmatic logic beyond string formatting.

Name Metaprefix URI
Cluster of orthologous genes cog
Bioregistry bioregistry miriam
Extra Providers

Additional providers curated in the Bioregistry are listed here.

Code Name URL
bio2rdf Bio2RDF