CIViC Molecular Profiles are combinations of one or more CIViC variants. Most Molecular Profiles are “Simple” Molecular Profiles comprised of a single variant. In most cases, these can be considered equivalent to the CIViC concept of a Variant. However, increasingly clinical significance must be considered in the context of multiple variants simultaneously. Complex Molecular Profiles in CIViC allow for curation of such variant combinations. Regardless of the nature of the Molecular Profile (Simple or Complex), it must have a Predictive, Prognostic, Predisposing, Diagnostic, Oncogenic, or Functional clinical relevance to be entered in CIViC.

Missing Contact
Pattern for Local Unique Identifiers

Local identifiers in CIViC Molecular Profile should match this regular expression:

Example Local Unique Identifier
559   Resolve
Pattern for CURIES

Compact URIs (CURIEs) constructed from CIViC Molecular Profile should match this regular expression:

Example CURIE
Metaregistry CIViC Molecular Profile

The metaregistry provides mappings between the Bioregistry and other registries. There are 1 mappings to external registries for civic.mpid with 1 unique external prefixes.

Registry Name Registry Metaprefix External Prefix Curate logo miriam civic.mpid

Providers are various services that resolve CURIEs to URLs. The example CURIE civic.mpid:559 is used to demonstrate the provides available for civic.mpid. Generation of OLS and BioPortal URLs requires additional programmatic logic beyond string formatting.

Name Metaprefix URI
CIViC Molecular Profile civic.mpid
Bioregistry bioregistry miriam