COGs stands for Clusters of Orthologous Genes. The database was initially created in 1997 (Tatusov et al., PMID: 9381173) followed by several updates, most recently in 2014 (Galperin et al., PMID: 25428365). The current update includes complete genomes of 1,187 bacteria and 122 archaea that map into 1,234 genera. The new features include ~250 updated COG annotations with corresponding references and PDB links, where available; new COGs for proteins involved in CRISPR-Cas immunity, sporulation, and photosynthesis, and the lists of COGs grouped by pathways and functional systems.
The metaregistry provides mappings between the Bioregistry and other registries. There are
2 mappings to external registries for
|Biolink Model Registry||
|Gene Ontology Registry||
Providers are various services that resolve CURIEs to URLs. The example CURIE
cog:COG0001 is used to demonstrate the provides available for
cog. Generation of OLS and BioPortal URLs requires additional programmatic
logic beyond string formatting.
|Cluster of orthologous genes||