CATH is a classification of protein structural domains. We group protein domains into superfamilies when there is sufficient evidence they have diverged from a common ancestor. CATH can be used to predict structural and functional information directly from protein sequence.

Prefix

cath

Keywords

biology classification evolutionary biology protein structure

Links

Homepage

Contact

Christine Orengo   0000-0002-7141-8936

Pattern for Local Unique Identifiers

Local identifiers in CATH Protein Structural Domain Superfamily should match this regular expression:
^[1-6]\.[0-9]+\.[0-9]+\.[0-9]+$

Example Local Unique Identifier

1.10.8.10   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from CATH Protein Structural Domain Superfamily should match this regular expression:
^cath:[1-6]\.[0-9]+\.[0-9]+\.[0-9]+$

Example CURIE

cath:1.10.8.10

Publications

• 1997 CATH--a hierarchic classification of protein domain structures
• 2021 CATH: increased structural coverage of functional space
• 2019 CATH: expanding the horizons of structure-based functional annotations for genome sequences
• 2018 Gene3D: Extensive prediction of globular domains in proteins
• 2016 CATH: an expanded resource to predict protein function through structure and sequence
• 2016 Functional classification of CATH superfamilies: a domain-based approach for protein function annotation
• 2015 The history of the CATH structural classification of protein domains
• 2014 CATH: comprehensive structural and functional annotations for genome sequences
• 2002 The CATH protein family database: a resource for structural and functional annotation of genomes

A summary of the relations in the Bioregistry schema can be found here.

Has Parts (bfo:0000051 )

cath.superfamily

The metaregistry provides mappings between the Bioregistry and other registries. There are 8 mappings to external registries for this resource with 5 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 1.10.8.10 is used to demonstrate the providers available for CATH Protein Structural Domain Superfamily. A guide for curating additional providers can be found here.

Additional providers curated in the Bioregistry are listed here. These are typically inherited from Identifiers.org or Prefix Commons, and need extra curation.