Gene
sorbs1
- ID
- ZDB-GENE-090313-168
- Name
- sorbin and SH3 domain containing 1
- Symbol
- sorbs1 Nomenclature History
- Previous Names
-
- cb01g02
- si:dkey-103j14.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- null
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Targeting Reagent | Created Alleles | Citations |
---|---|---|
CRISPR1-sorbs1 | Veloso et al., 2024 | |
MO1-sorbs1 | N/A | Veloso et al., 2024 |
MO2-sorbs1 | N/A | Veloso et al., 2024 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Endophilin/SH3RF | Regulator of chromosome condensation, RCC1 | SH3 domain | SH3-like domain superfamily | SoHo domain |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M6Z435 | InterPro | 1059 | |||||
UniProtKB:A0A8M6Z9S5 | InterPro | 1009 | |||||
UniProtKB:A0A8M9PFI6 | InterPro | 533 | |||||
UniProtKB:A0A8M9PFJ2 | InterPro | 472 | |||||
UniProtKB:A0A8M9PSG3 | InterPro | 512 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
sorbs1-202
(1)
|
Ensembl | 6,034 nt | ||
mRNA |
sorbs1-203
(1)
|
Ensembl | 579 nt | ||
mRNA |
sorbs1-204
(1)
|
Ensembl | 582 nt | ||
mRNA |
sorbs1-205
(1)
|
Ensembl | 571 nt | ||
ncRNA |
sorbs1-008
(1)
|
Ensembl | 619 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-103J14 | ZFIN Curated Data | |
Contained in | BAC | DKEY-226B20 | ZFIN Curated Data | |
Encodes | EST | cb01g02 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_068213040 (1) | 8156 nt | ||
Genomic | RefSeq:NW_018395309 (1) | 375908 nt | ||
Polypeptide | UniProtKB:A0A8M9QFZ8 (1) | 1064 aa |
- Veloso, A., Bleuart, A., Conrard, L., Orban, T., Bruyr, J., Cabochette, P., Germano, R.F.V., Schevenels, G., Bernard, A., Zindy, E., Demeyer, S., Vanhollebeke, B., Dequiedt, F., Martin, M. (2024) The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish. BMC Biology. 22:5151
- Gu, Q., Ali, S.F., Kanungo, J. (2020) Effects of acetyl L-carnitine on zebrafish embryos: Phenotypic and gene expression studies. Journal of applied toxicology : JAT. 41(2):256-264
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