Gene
ubc
- ID
- ZDB-GENE-061110-88
- Name
- ubiquitin C
- Symbol
- ubc Nomenclature History
- Previous Names
-
- im:7042025
- wu:fb37h06
- zgc:153686 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBC (ubiquitin C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6898771 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ubiquitin and ubiquitin-like | Ubiquitin conserved site | Ubiquitin domain | Ubiquitin-like domain | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:F1QHN6 | InterPro | 533 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-226M13 | ZFIN Curated Data | |
| Encodes | EST | fb17g05 | Rauch et al., 2003 | |
| Encodes | EST | fb37h06 | ||
| Encodes | EST | IMAGE:6898771 | ||
| Encodes | EST | IMAGE:7042025 | ||
| Encodes | cDNA | MGC:153686 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001077804 (1) | 1835 nt | ||
| Genomic | GenBank:CU463283 (2) | 121463 nt | ||
| Polypeptide | UniProtKB:F1QHN6 (1) | 533 aa |
- Kranert, K., Woźny, M., Podlasz, P., Wąsowicz, K., Brzuzan, P. (2022) MiR92b-3p synthetic analogue impairs zebrafish embryonic development, leading to ocular defects, decreased movement and hatching rate, and increased mortality. Journal of applied genetics. 64(1):145-157
- Liu, S., Hu, G., Luo, S., Wu, W., Zhou, Q., Jin, R., Zhang, Y., Ruan, H., Huang, H., Li, H. (2022) Insights into the evolution of the ISG15 and UBA7 system. Genomics. 114(2):110302
- Crespo, D., Assis, L.H.C., Zhang, Y.T., Safian, D., Furmanek, T., Skaftnesmo, K.O., Norberg, B., Ge, W., Choi, Y.C., den Broeder, M.J., Legler, J., Bogerd, J., Schulz, R.W. (2021) Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells. Communications biology. 4:204
- Burgess, J., Burrows, J.T., Sadhak, R., Chiang, S., Weiss, A., D'Amata, C., Molinaro, A.M., Zhu, S., Long, M., Hu, C., Krause, H.M., Pearson, B.J. (2020) An optimized QF-binary expression system for use in zebrafish. Developmental Biology. 465(2):144-156
- Dobrzycki, T., Mahony, C.B., Krecsmarik, M., Koyunlar, C., Rispoli, R., Peulen-Zink, J., Gussinklo, K., Fedlaoui, B., de Pater, E., Patient, R., Monteiro, R. (2020) Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis. Communications biology. 3:71
- Bonkhofer, F., Rispoli, R., Pinheiro, P., Krecsmarik, M., Schneider-Swales, J., Tsang, I.H.C., de Bruijn, M., Monteiro, R., Peterkin, T., Patient, R. (2019) Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium. Nature communications. 10:3577
- Crespo, D., Assis, L.H.C., van de Kant, H.J.G., de Waard, S., Safian, D., Lemos, M.S., Bogerd, J., Schulz, R.W. (2019) Endocrine and local signaling interact to regulate spermatogenesis in zebrafish: Follicle-stimulating hormone, retinoic acid and androgens. Development (Cambridge, England). 146(21):
- Crespo, D., Lemos, M.S., Zhang, Y.T., Safian, D., Norberg, B., Bogerd, J., Schulz, R. (2019) PGE2 inhibits spermatogonia differentiation in zebrafish: interaction with Fsh and an androgen. The Journal of endocrinology. 244(1):163-175
- Kaushik, K., Sivadas, A., Vellarikkal, S.K., Verma, A., Jayarajan, R., Pandey, S., Sethi, T., Maiti, S., Scaria, V., Sivasubbu, S. (2018) RNA secondary structure profiling in zebrafish reveals unique regulatory features. BMC Genomics. 19:147
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
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