Gene
adipoqb
- ID
- ZDB-GENE-060825-220
- Name
- adiponectin, C1Q and collagen domain containing, b
- Symbol
- adipoqb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Is expressed in several structures, including adipose tissue; ball; liver; notochord; and pancreas. Human ortholog(s) of this gene implicated in several diseases, including cardiovascular system disease (multiple); liver disease (multiple); primary open angle glaucoma; prostate adenocarcinoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (adiponectin, C1Q and collagen domain containing).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Adiponectin deficiency | 612556 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | C1q domain | Collagen/C1q domain-containing | Collagen triple helix repeat | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q0P415 | InterPro | 275 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adipoqb-201
(1)
|
Ensembl | 1,118 nt | ||
| mRNA |
adipoqb-202
(1)
|
Ensembl | 831 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-166G17 | ||
| Encodes | cDNA | MGC:153584 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192626 | ZFIN Curated Data |
1 - 3 of 3
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001045425 (1) | 1119 nt | ||
| Genomic | GenBank:CR450747 (2) | 150453 nt | ||
| Polypeptide | UniProtKB:Q0P415 (1) | 275 aa |
- Guggeri, L., Sosa-Redaelli, I., Cárdenas-Rodríguez, M., Alonso, M., González, G., Naya, H., Prieto-Echagüe, V., Lepanto, P., Badano, J.L. (2024) Follistatin like-1 (Fstl1) regulates adipose tissue development in zebrafish. Adipocyte. 13:24358622435862
- Zhong, S., Chen, L., Li, X., Wang, X., Ji, G., Sun, C., Liu, Z. (2023) Bmp8a deletion leads to obesity through regulation of lipid metabolism and adipocyte differentiation. Communications biology. 6:824824
- Lepanto, P., Levin-Ferreyra, F., Koziol, U., Malacrida, L., Badano, J.L. (2021) Insights into in vivo adipocyte differentiation through cell-specific labeling in zebrafish. Biology Open. 10(9):
- Zhou, Y., Guo, W., Lei, L., Sun, Y., Li, R., Guo, Y., Yang, L., Shi, X., Han, J., Zhou, B. (2021) Bis(2-ethylhexyl)-tetrabromophthalate induces zebrafish obesity by altering the brain-gut axis and intestinal microbial composition. Environmental pollution (Barking, Essex : 1987). 290:118127
- Fei, F., Sun, S., Li, Q., Pei, Z., Wang, L., Zhang, R., Luo, F., Yu, M., Wang, X. (2020) Combinatorial normalization of liver-derived cytokine pathways alleviates hepatic tumor-associated cachexia in zebrafish. Cancer research. 81(4):873-884
- Landgraf, K., Klöting, N., Gericke, M., Maixner, N., Guiu-Jurado, E., Scholz, M., Witte, A.V., Beyer, F., Schwartze, J.T., Lacher, M., Villringer, A., Kovacs, P., Rudich, A., Blüher, M., Kiess, W., Körner, A. (2020) The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG. Cell Reports. 33:108295
- Guo, W., Han, J., Wu, S., Shi, X., Wang, Q., Zhou, B. (2019) Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate affects lipid metabolism in zebrafish larvae via DNA methylation modification. Environmental science & technology. 54(1):355-363
- Löhr, H., Hess, S., Pereira, M.M.A., Reinoß, P., Leibold, S., Schenkel, C., Wunderlich, C.M., Kloppenburg, P., Brüning, J.C., Hammerschmidt, M. (2018) Diet-Induced Growth Is Regulated via Acquired Leptin Resistance and Engages a Pomc-Somatostatin-Growth Hormone Circuit. Cell Reports. 23:1728-1741
- den Broeder, M.J., Moester, M.J.B., Kamstra, J.H., Cenijn, P.H., Davidoiu, V., Kamminga, L.M., Ariese, F., de Boer, J.F., Legler, J. (2017) Altered Adipogenesis in Zebrafish Larvae Following High Fat Diet and Chemical Exposure Is Visualised by Stimulated Raman Scattering Microscopy. International Journal of Molecular Sciences. 18(4)
- Martella, A., Silvestri, C., Maradonna, F., Gioacchini, G., Allarà, M., Radaelli, G., Overby, D.R., Di Marzo, V., Carnevali, O. (2016) Bisphenol A induces fatty liver by an endocannabinoid-mediated positive feedback loop. Endocrinology. 157(5):1751-63
1 - 10 of 18
Show