Gene

acaca

ID
ZDB-GENE-060526-74
Name
acetyl-CoA carboxylase alpha
Symbol
acaca Nomenclature History
Previous Names
  • acc (1)
  • fj43d01
  • im:7138837 (1)
  • si:ch211-199d18.1
  • wu:fj43d01 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable acetyl-CoA carboxylase activity. Acts upstream of or within response to (R)-carnitine. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Is expressed in female organism; liver; male organism; subcutaneous fat; and visceral fat. Orthologous to human ACACA (acetyl-CoA carboxylase alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
37 figures from 32 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acaca Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Acetyl-CoA carboxylase deficiency 613933
1 - 1 of 1
Associated With acaca Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR001882 Biotin-binding site
Domain IPR000089 Biotin/lipoyl attachment
Domain IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
Domain IPR005481 Biotin carboxylase-like, N-terminal domain
Domain IPR005482 Biotin carboxylase, C-terminal
1 - 5 of 18 Show all
Domain Details Per Protein
Protein Additional Resources Length Acetyl-CoA carboxylase Acetyl-CoA carboxylase, BT domain Acetyl-CoA carboxylase, central domain Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta Acetyl-coenzyme A carboxyltransferase, C-terminal Acetyl-coenzyme A carboxyltransferase, N-terminal ATP-grasp fold ATP-grasp fold, subdomain 1 Biotin-binding site Biotin carboxylase, C-terminal Biotin carboxylase-like, N-terminal domain Biotin carboxylation domain Biotin/lipoyl attachment Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain ClpP/crotonase-like domain superfamily Pre-ATP-grasp domain superfamily Rudiment single hybrid motif Single hybrid motif
UniProtKB:A0A8M6YZ52 InterPro 2349
UniProtKB:A0A8M9PK80 InterPro 2425
UniProtKB:A0A8M9QE20 InterPro 2326
UniProtKB:A0A2R8QJA0 InterPro 2375
UniProtKB:A0A8M9Q3F9 InterPro 2348
1 - 5 of 15 Show all
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA acaca-201 (1)
Ensembl
Ensembl 8,344 nt
ZFIN BLAST
mRNA acaca-202 (1)
Ensembl
Ensembl 8,498 nt
ZFIN BLAST
ncRNA acaca-002 (1)
Ensembl
Ensembl 662 nt
ZFIN BLAST
ncRNA acaca-003 (1)
Ensembl
Ensembl 514 nt
ZFIN BLAST
ncRNA acaca-004 (1)
Ensembl
Ensembl 834 nt
ZFIN BLAST
1 - 5 of 5
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab4-acaca polyclonal Rabbit
  • WB
 Sangon Biotech
2
1 - 1 of 1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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