Gene
pltp
- ID
- ZDB-GENE-040801-22
- Name
- phospholipid transfer protein
- Symbol
- pltp Nomenclature History
- Previous Names
-
- zgc:100903
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable ceramide transfer activity; phosphatidic acid transfer activity; and phosphatidylethanolamine transfer activity. Predicted to be involved in ceramide transport; high-density lipoprotein particle remodeling; and phospholipid transport. Predicted to be active in extracellular space. Orthologous to human PLTP (phospholipid transfer protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa20831 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017954 | Lipid-binding serum glycoprotein, conserved site |
| Domain | IPR001124 | Lipid-binding serum glycoprotein, C-terminal |
| Domain | IPR017942 | Lipid-binding serum glycoprotein, N-terminal |
| Family | IPR030675 | Lipid binding protein BPI/LBP |
| Family | IPR032942 | BPI/LBP/Plunc family |
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Domain Details Per Protein
| Protein | Length | Bactericidal permeability-increasing protein, alpha/beta domain superfamily | BPI/LBP/Plunc family | Lipid binding protein BPI/LBP | Lipid-binding serum glycoprotein, conserved site | Lipid-binding serum glycoprotein, C-terminal | Lipid-binding serum glycoprotein, N-terminal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DEI0
|
486 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | CH1073-250A3 | ZFIN Curated Data | |
| Contained in | Fosmid | ZFOS-1333D1 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:100903 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001003519 (1) | 1855 nt | ||
| Genomic | GenBank:FP340256 (1) | 41319 nt | ||
| Polypeptide | UniProtKB:Q6DEI0 (1) | 486 aa |
- Freeburg, S.H., Shwartz, A., Kemény, L.V., Smith, C.J., Weeks, O., Miller, B.M., PenkoffLidbeck, N., Fisher, D.E., Evason, K.J., Goessling, W. (2024) Hepatocyte vitamin D receptor functions as a nutrient sensor that regulates energy storage and tissue growth in zebrafish. Cell Reports. 43:114393114393
- Niksirat, H., Siino, V., Steinbach, C., Levander, F. (2021) High-Resolution Proteomic Profiling Shows Sexual Dimorphism in Zebrafish Heart-Associated Proteins. Journal of Proteome Research. 20(8):4075-4088
- Huo, X., Li, H., Li, Z., Yan, C., Agrawal, I., Mathavan, S., Liu, J., Gong, Z. (2019) Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. Scientific Reports. 9:1509
- Moriya, S., Tahsin, N., Parhar, I.S. (2017) Bpifcl modulates kiss2 expression under the influence of 11-ketotestosterone in female zebrafish. Scientific Reports. 7:7926
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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