Gene
fabp6
- ID
- ZDB-GENE-040625-49
- Name
- fatty acid binding protein 6, ileal (gastrotropin)
- Symbol
- fabp6 Nomenclature History
- Previous Names
-
- I-BABP (1)
- zgc:92421
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Enables bile acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol and nucleus. Is expressed in digestive system; heart; and pleuroperitoneal region. Orthologous to human FABP6 (fatty acid binding protein 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calycin | Cytosolic fatty-acid binding | Intracellular lipid binding protein |
|---|---|---|---|---|
|
UniProtKB:Q6IMW5
|
131 |
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Interactions and Pathways
No data available
Plasmids
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(fabp6:Cre-ERT2) |
|
| 1 | Wei et al., 2023 | |
| Tg(fabp6:Dendra2-NTR) |
|
| 1 | Wei et al., 2023 | |
| Tg(fabp6:DsRed) |
|
| 1 | Wei et al., 2023 | |
| Tg(fabp6:EGFP,cryaa:mCherry) |
|
| 1 | (2) | |
| Tg(fabp6:H2B-mCherry) |
|
| 1 | Wei et al., 2023 | |
| Tg(fabp6:Kaede) |
|
| 1 | Wei et al., 2023 | |
| Tg(fabp6:LIFEACT-GFP) |
|
| 1 | Wei et al., 2023 | |
| Tg(fabp6-Mmu.Fos:GFP) |
|
| 2 | (4) |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-190F9 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:92421 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002076 (1) | 547 nt | ||
| Genomic | GenBank:CU855895 (1) | 120253 nt | ||
| Polypeptide | UniProtKB:Q6IMW5 (1) | 131 aa |
- Lv, H., Jin, Z., Wang, D., Guo, X., Wang, H., Yang, S. (2023) Erk5 functions in modulation of zebrafish intestinal permeability. Cell and tissue research. 393(2):281-296
- Ulhaq, Z.S., Ogino, Y., Tse, W.K.F. (2023) FGF8 rescues motor deficits in zebrafish model of limb-girdle muscular dystrophy R18. Biochemical and Biophysical Research Communications. 652:768376-83
- Wei, X., Tan, X., Chen, Q., Jiang, Y., Wu, G., Ma, X., Fu, J., Li, Y., Gang, K., Yang, Q., Ni, R., He, J., Luo, L. (2023) Extensive jejunal injury is repaired by migration and transdifferentiation of ileal enterocytes in zebrafish. Cell Reports. 42:112660112660
- Yao, J., Cai, Y., Chen, Z., Wang, X., Lai, X., Pan, L., Li, Y., Wang, S. (2023) DExH/D RNA helicase 15 regulates zebrafish intestinal development through the Wnt signaling pathway. Genomics. 115(2):110578
- Gao, Y., Jin, Q., Gao, C., Chen, Y., Sun, Z., Guo, G., Peng, J. (2022) Unraveling Differential Transcriptomes and Cell Types in Zebrafish Larvae Intestine and Liver. Cells. 11(20):
- Li, Y.F., Cheng, T., Zhang, Y.J., Fu, X.X., Mo, J., Zhao, G.Q., Xue, M.G., Zhuo, D.H., Xing, Y.Y., Huang, Y., Sun, X.Z., Wang, D., Liu, X., Dong, Y., Zhu, X.S., He, F., Ma, J., Chen, D., Jin, X., Xu, P.F. (2022) Mycn regulates intestinal development through ribosomal biogenesis in a zebrafish model of Feingold syndrome 1. PLoS Biology. 20:e3001856
- Ma, J., Shao, X., Geng, F., Liang, S., Yu, C., Zhang, R. (2022) Ercc2/Xpd deficiency results in failure of digestive organ growth in zebrafish with elevated nucleolar stress. iScience. 25:104957
- Mu, X., Qi, S., Wang, H., Yuan, L., Wang, C., Li, Y., Qiu, J. (2022) Bisphenol analogues induced metabolic effects through eliciting intestinal cell heterogeneous response. Environment International. 165:107287
- Zhao, G., Hu, J., Gao, M., Zhu, Y., Hong, Y. (2022) Excessive selenium affects neural development and locomotor behavior of zebrafish embryos. Ecotoxicology and environmental safety. 238:113611
- Meng, H., Shang, Y., Cheng, Y., Wang, K., Yu, J., Cao, P., Fan, S., Li, Y., Cui, J. (2021) Knockout of zebrafish colony-stimulating factor 1 receptor by CRISPR/Cas9 affects metabolism and locomotion capacity. Biochemical and Biophysical Research Communications. 551:93-99
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