Gene
cpt1ab
- ID
- ZDB-GENE-030131-3250
- Name
- carnitine palmitoyltransferase 1Ab (liver)
- Symbol
- cpt1ab Nomenclature History
- Previous Names
-
- fc31g06
- si:ch211-236l14.3
- wu:fc31g06 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable carnitine O-palmitoyltransferase activity. Acts upstream of or within regulation of fatty acid beta-oxidation. Predicted to be located in membrane. Predicted to be active in mitochondrion. Is expressed in cardiac ventricle and liver. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency and lipid metabolism disorder. Orthologous to human CPT1A (carnitine palmitoyltransferase 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zecchin et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| carnitine palmitoyltransferase I deficiency | Alliance | CPT deficiency, hepatic, type IA | 255120 |
1 - 1 of 1
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR032476 | Carnitine O-palmitoyltransferase, N-terminal |
| Domain | IPR039551 | Choline/carnitine acyltransferase domain |
| Family | IPR000542 | Acyltransferase ChoActase/COT/CPT |
| Homologous_superfamily | IPR023213 | Chloramphenicol acetyltransferase-like domain superfamily |
| Homologous_superfamily | IPR042231 | Choline/Carnitine o-acyltransferase, domain 2 |
1 - 5 of 5
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyltransferase ChoActase/COT/CPT | Carnitine O-palmitoyltransferase, N-terminal | Chloramphenicol acetyltransferase-like domain superfamily | Choline/carnitine acyltransferase domain | Choline/Carnitine o-acyltransferase, domain 2 |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PEG9 | InterPro | 775 | |||||
| UniProtKB:A0A8M9PNB1 | InterPro | 428 | |||||
| UniProtKB:A0A8M9PR97 | InterPro | 774 | |||||
| UniProtKB:K7DY29 | InterPro | 774 | |||||
| UniProtKB:A0A8M9PXF3 | InterPro | 428 |
1 - 5 of 6 Show all
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cpt1ab-201
(1)
|
Ensembl | 5,195 nt | ||
| mRNA |
cpt1ab-202
(1)
|
Ensembl | 3,570 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available