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gtf2a2 general transcription factor IIA, 2 [ Danio rerio (zebrafish) ]

Gene ID: 798997, updated on 27-Mar-2024

Summary

Official Symbol
gtf2a2provided by ZNC
Official Full Name
general transcription factor IIA, 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-513
See related
Ensembl:ENSDARG00000053685 AllianceGenome:ZFIN:ZDB-GENE-050522-513
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110584
Summary
Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to act upstream of or within transcription initiation from RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex. Orthologous to human GTF2A2 (general transcription factor IIA subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 7
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (29351500..29356062, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (29080350..29084912, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene RAB8B, member RAS oncogene family Neighboring gene transient receptor potential cation channel, subfamily M, member 1a Neighboring gene microRNA 204-2 Neighboring gene uncharacterized LOC100000228 Neighboring gene serine/threonine-protein kinase pim-3-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC110584

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables TBP-class protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in RNA polymerase II preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of transcription factor TFIIA complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transcription factor TFIIA complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transcription initiation factor IIA subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020605.1NP_001018441.1  transcription initiation factor IIA subunit 2

    See identical proteins and their annotated locations for NP_001018441.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095322
    UniProtKB/TrEMBL
    A0A2R8RQ43, A0A2R8S0A4, Q503H9
    Related
    ENSDARP00000070238.2, ENSDART00000075757.4
    Conserved Domains (1) summary
    COG5123
    Location:3103
    TOA2; Transcription initiation factor IIA, gamma subunit [Transcription]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    29351500..29356062 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394694.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    236020..240588 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395266.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    58012..62578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)