U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PAK4 p21 (RAC1) activated kinase 4 [ Gallus gallus (chicken) ]

Gene ID: 770462, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Symbol
PAK4provided by CGNC
Full Name
p21 (RAC1) activated kinase 4provided by CGNC
Primary source
CGNC:10652
See related
Ensembl:ENSGALG00010009155
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 38
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 38 NC_052569.1 (28696..48300, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 38 NC_052610.1 (76588..96188, complement)

Chromosome 38 - NC_052569.1Genomic Context describing neighboring genes Neighboring gene sterile alpha motif domain containing 4B Neighboring gene leucine rich repeat and fibronectin type III domain containing 1 Neighboring gene syncollin Neighboring gene mitochondrial ribosomal protein S12 Neighboring gene seryl-tRNA synthetase 2, mitochondrial Neighboring gene NFKB inhibitor beta

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
serine/threonine-protein kinase PAK 4
Names
p21 protein (Cdc42/Rac)-activated kinase 4
p21(CDKN1A)-activated kinase 4
XP_025000253.1
XP_025000254.1
XP_025000256.1
XP_025000257.1
XP_040511055.1
XP_040550142.1
XP_040550143.1
XP_040550144.1
XP_040550145.1
XP_040550146.1
XP_046761037.1
XP_046761038.1
XP_046761040.1
XP_046761041.1
XP_046761042.1
XP_046761043.1
XP_046761044.1
XP_046761045.1
XP_046790336.1
XP_046790337.1
XP_046790338.1
XP_046790339.1
XP_046790340.1
XP_046790341.1
XP_046790342.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052569.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    28696..48300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040655121.2 → XP_040511055.1  serine/threonine-protein kinase PAK 4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Related
    ENSGALP00010012515.1, ENSGALT00010021868.1
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 642
    PKc_like; Protein Kinases, catalytic domain

  2. XM_025144489.3 → XP_025000257.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain

  3. XM_025144485.3 → XP_025000253.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain

  4. XM_025144486.3 → XP_025000254.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain

  5. XM_046905085.1 → XP_046761041.1  serine/threonine-protein kinase PAK 4 isoform X1

  6. XM_046905088.1 → XP_046761044.1  serine/threonine-protein kinase PAK 4 isoform X1

  7. XM_046905086.1 → XP_046761042.1  serine/threonine-protein kinase PAK 4 isoform X1

  8. XM_046905082.1 → XP_046761038.1  serine/threonine-protein kinase PAK 4 isoform X4

    Related
    ENSGALP00010012509.1, ENSGALT00010021859.1

  9. XM_046905084.1 → XP_046761040.1  serine/threonine-protein kinase PAK 4 isoform X1

  10. XM_046905081.1 → XP_046761037.1  serine/threonine-protein kinase PAK 4 isoform X3

    Related
    ENSGALP00010012507.1, ENSGALT00010021854.1

  11. XM_046905089.1 → XP_046761045.1  serine/threonine-protein kinase PAK 4 isoform X1

  12. XM_046905087.1 → XP_046761043.1  serine/threonine-protein kinase PAK 4 isoform X1

  13. XM_025144488.3 → XP_025000256.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052610.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    76588..96188 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040694209.2 → XP_040550143.1  serine/threonine-protein kinase PAK 4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 642
    PKc_like; Protein Kinases, catalytic domain

  2. XM_040694208.2 → XP_040550142.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain

  3. XM_040694210.2 → XP_040550144.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain

  4. XM_040694211.2 → XP_040550145.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain

  5. XM_046934383.1 → XP_046790339.1  serine/threonine-protein kinase PAK 4 isoform X1

  6. XM_046934385.1 → XP_046790341.1  serine/threonine-protein kinase PAK 4 isoform X1

  7. XM_046934381.1 → XP_046790337.1  serine/threonine-protein kinase PAK 4 isoform X4

  8. XM_046934382.1 → XP_046790338.1  serine/threonine-protein kinase PAK 4 isoform X1

  9. XM_046934380.1 → XP_046790336.1  serine/threonine-protein kinase PAK 4 isoform X3

  10. XM_046934386.1 → XP_046790342.1  serine/threonine-protein kinase PAK 4 isoform X1

  11. XM_046934384.1 → XP_046790340.1  serine/threonine-protein kinase PAK 4 isoform X1

  12. XM_040694212.2 → XP_040550146.1  serine/threonine-protein kinase PAK 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2G7
    Conserved Domains (2) summary
    cd01093
    Location:9 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:351 → 651
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous