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CHEK1 checkpoint kinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 739836, updated on 3-Apr-2024

Summary

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Official Symbol
CHEK1provided by VGNC
Official Full Name
checkpoint kinase 1provided by VGNC
Primary source
VGNC:VGNC:11294
Locus tag
CK820_G0015504
See related
Ensembl:ENSPTRG00000004446
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (127563797..127614786)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (126781098..126831574)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807284 Neighboring gene U6 spliceosomal RNA Neighboring gene EI24 autophagy associated transmembrane protein Neighboring gene STT3 oligosaccharyltransferase complex catalytic subunit A Neighboring gene U2 spliceosomal RNA Neighboring gene acrosomal vesicle protein 1 Neighboring gene prostate and testis expressed 2 Neighboring gene prostate and testis expressed 1 Neighboring gene prostate and testis expressed 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase Chk1
Names
CHK1 checkpoint homolog
XP_001146296.1
XP_001146365.1
XP_001146525.1
XP_009422718.1
XP_016777729.1
XP_054517679.1
XP_063639560.1
XP_063639561.1
XP_063639562.1
XP_063639563.1
XP_063639564.1
XP_063639565.1
XP_063639566.1
XP_063639567.1
XP_063639568.1
XP_063639569.1
XP_063639570.1
XP_063639571.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    127563797..127614786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001146525.8 → XP_001146525.1  serine/threonine-protein kinase Chk1 isoform X1

    See identical proteins and their annotated locations for XP_001146525.1

    UniProtKB/TrEMBL
    A0A2I3T978, A0A2J8N1G1, A0A2J8N1H2, A0A6D2XM30, A0A6D2XVE7, H2Q525
    Related
    ENSPTRP00000007593.3
    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  2. XM_063783492.1 → XP_063639562.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  3. XM_063783491.1 → XP_063639561.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  4. XM_063783490.1 → XP_063639560.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  5. XM_063783501.1 → XP_063639571.1  serine/threonine-protein kinase Chk1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8N1H9

  6. XM_063783499.1 → XP_063639569.1  serine/threonine-protein kinase Chk1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8N1H9

  7. XM_063783495.1 → XP_063639565.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  8. XM_063783493.1 → XP_063639563.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  9. XM_001146296.8 → XP_001146296.1  serine/threonine-protein kinase Chk1 isoform X1

    See identical proteins and their annotated locations for XP_001146296.1

    UniProtKB/TrEMBL
    A0A2I3T978, A0A2J8N1G1, A0A2J8N1H2, A0A6D2XM30, A0A6D2XVE7, H2Q525
    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  10. XM_009424443.5 → XP_009422718.1  serine/threonine-protein kinase Chk1 isoform X1

    See identical proteins and their annotated locations for XP_009422718.1

    UniProtKB/TrEMBL
    A0A2I3T978, A0A2J8N1G1, A0A2J8N1H2, A0A6D2XM30, A0A6D2XVE7, H2Q525
    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  11. XM_063783500.1 → XP_063639570.1  serine/threonine-protein kinase Chk1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8N1H9

  12. XM_063783497.1 → XP_063639567.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  13. XM_063783498.1 → XP_063639568.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  14. XM_001146365.8 → XP_001146365.1  serine/threonine-protein kinase Chk1 isoform X1

    See identical proteins and their annotated locations for XP_001146365.1

    UniProtKB/TrEMBL
    A0A2I3T978, A0A2J8N1G1, A0A2J8N1H2, A0A6D2XM30, A0A6D2XVE7, H2Q525
    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  15. XM_063783494.1 → XP_063639564.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  16. XM_063783496.1 → XP_063639566.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  17. XM_054661704.2 → XP_054517679.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8N1G1, A0A6D2XM30, H2Q525

  18. XM_016922240.4 → XP_016777729.1  serine/threonine-protein kinase Chk1 isoform X3

    UniProtKB/TrEMBL
    A0A2I3RRH9
    Related
    ENSPTRP00000067296.1
Nucleotide Protein
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