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Snrpf small nuclear ribonucleoprotein polypeptide F [ Mus musculus (house mouse) ]

Gene ID: 69878, updated on 5-Mar-2024

Summary

Official Symbol
Snrpfprovided by MGI
Official Full Name
small nuclear ribonucleoprotein polypeptide Fprovided by MGI
Primary source
MGI:MGI:1917128
See related
Ensembl:ENSMUSG00000020018 AllianceGenome:MGI:1917128
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SMF; sm-F; snRNP-F; 2010013O18Rik
Summary
Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to act upstream of or within mRNA processing. Predicted to be located in cytosol and nucleus. Predicted to be part of several cellular components, including methylosome; nucleus; and pICln-Sm protein complex. Is expressed in central nervous system and sensory organ. Orthologous to human SNRPF (small nuclear ribonucleoprotein polypeptide F). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 72.6), CNS E11.5 (RPKM 60.9) and 28 other tissues See more
Orthologs
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Genomic context

Location:
10 C2; 10 48.57 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (93418891..93425520, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (93583029..93589658, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene histidine ammonia lyase Neighboring gene STARR-positive B cell enhancer ABC_E8360 Neighboring gene STARR-seq mESC enhancer starr_27586 Neighboring gene amidohydrolase domain containing 1 Neighboring gene coiled-coil domain containing 38 Neighboring gene STARR-positive B cell enhancer ABC_E6903 Neighboring gene RIKEN cDNA 4933408J17 gene Neighboring gene STARR-positive B cell enhancer ABC_E6904 Neighboring gene STARR-positive B cell enhancer ABC_E9800 Neighboring gene STARR-seq mESC enhancer starr_27587 Neighboring gene netrin 4 Neighboring gene ribosomal protein L29 pseudogene Neighboring gene predicted gene 15915

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA splicing ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
involved_in spliceosomal snRNP assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of SMN-Sm protein complex ISO
Inferred from Sequence Orthology
more info
 
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U1 snRNP ISO
Inferred from Sequence Orthology
more info
 
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
part_of U4 snRNP ISO
Inferred from Sequence Orthology
more info
 
part_of U4/U6 x U5 tri-snRNP complex ISO
Inferred from Sequence Orthology
more info
 
part_of U7 snRNP ISO
Inferred from Sequence Orthology
more info
 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of methylosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of pICln-Sm protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of pICln-Sm protein complex ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
part_of small nuclear ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
part_of spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
small nuclear ribonucleoprotein F
Names
sm protein F

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027246.1NP_081522.1  small nuclear ribonucleoprotein F

    See identical proteins and their annotated locations for NP_081522.1

    Status: VALIDATED

    Source sequence(s)
    AK008240, BC066015, BQ748807
    Consensus CDS
    CCDS48672.1
    UniProtKB/Swiss-Prot
    P62307
    UniProtKB/TrEMBL
    Q3UX80, Q497K3
    Related
    ENSMUSP00000020203.7, ENSMUST00000020203.7
    Conserved Domains (1) summary
    cd01722
    Location:674
    Sm_F; Sm protein F

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    93418891..93425520 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)