Chst14 carbohydrate sulfotransferase 14 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Chst14provided by RGD
Official Full Name: carbohydrate sulfotransferase 14provided by RGD
Primary source: RGD:1585023
See related: AllianceGenome:RGD:1585023
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in dermatan sulfate proteoglycan metabolic process. Predicted to act upstream of or within dermatan sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 1. Orthologous to human CHST14 (carbohydrate sulfotransferase 14). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: 3q35

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (126370348..126372405)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (105916481..105918538)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (110734105..110736162)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

Chst14 (e-PCR), detects polymorphism
- UniSTS:516435

RH136894 (e-PCR)
- UniSTS:218983

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables N-acetylgalactosamine 4-O-sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in carbohydrate biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within dermatan sulfate biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in dermatan sulfate proteoglycan metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in dermatan sulfate proteoglycan metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: carbohydrate sulfotransferase 14

Names: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; dermatan 4 sulfotransferase 1

NP_001103109.1

EC 2.8.2.-

EC 2.8.2.35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.