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FBXW2 F-box and WD repeat domain containing 2 [ Canis lupus familiaris (dog) ]

Gene ID: 610990, updated on 5-Mar-2024

Summary

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Official Symbol
FBXW2provided by VGNC
Official Full Name
F-box and WD repeat domain containing 2provided by VGNC
Primary source
VGNC:VGNC:40794
See related
Ensembl:ENSCAFG00845014676
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (74975650..74987359, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (72239197..72262975, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (74240963..74264787, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (73444778..73496255, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (73503250..73527011, complement)

Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene multiple EGF like domains 9 Neighboring gene uncharacterized LOC119881632 Neighboring gene proteasome 26S subunit, non-ATPase 5 Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene cutA divalent cation tolerance like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
F-box/WD repeat-containing protein 2; LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051815.1 Reference ROS_Cfam_1.0

    Range
    74975650..74987359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038682580.1 → XP_038538508.1  F-box/WD repeat-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NRH6
    Related
    ENSCAFP00845020690.1, ENSCAFT00845026245.1
    Conserved Domains (3) summary
    smart00256
    Location:60 → 94
    FBOX; A Receptor for Ubiquitination Targets
    sd00039
    Location:189 → 223
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:140 → 228
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049271.1 Alternate UMICH_Zoey_3.1

    Range
    73444778..73496255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038491116.1 → XP_038347044.1  F-box/WD repeat-containing protein 2 isoform X3

  2. XM_038491115.1 → XP_038347043.1  F-box/WD repeat-containing protein 2 isoform X2

    Conserved Domains (3) summary
    smart00256
    Location:60 → 94
    FBOX; A Receptor for Ubiquitination Targets
    cd00200
    Location:140 → 447
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:151 → 185
    7WD40; WD40 repeat [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

    Range
    73503250..73527011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038617123.1 → XP_038473051.1  F-box/WD repeat-containing protein 2 isoform X4

    Conserved Domains (3) summary
    smart00256
    Location:60 → 94
    FBOX; A Receptor for Ubiquitination Targets
    cd00200
    Location:140 → 447
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:151 → 185
    7WD40; WD40 repeat [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

    Range
    74240963..74264787 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038553248.1 → XP_038409176.1  F-box/WD repeat-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0K7N0, A0A8C0S9J6, A0A8P0N6E5
    Conserved Domains (3) summary
    smart00256
    Location:60 → 94
    FBOX; A Receptor for Ubiquitination Targets
    cd00200
    Location:140 → 447
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:151 → 185
    7WD40; WD40 repeat [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    72239197..72262975 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038655928.1 → XP_038511856.1  LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8P0N6E5
    Conserved Domains (3) summary
    smart00256
    Location:60 → 94
    FBOX; A Receptor for Ubiquitination Targets
    cd00200
    Location:140 → 447
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:151 → 185
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
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