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MMP17 matrix metallopeptidase 17 [ Canis lupus familiaris (dog) ]

Gene ID: 609890, updated on 5-Mar-2024

Summary

Official Symbol
MMP17provided by VGNC
Official Full Name
matrix metallopeptidase 17provided by VGNC
Primary source
VGNC:VGNC:59062
See related
Ensembl:ENSCAFG00845028950
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 26
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (1072479..1091195, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (1054484..1073216, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (1029400..1048084, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (1009626..1028354, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (1106771..1124956, complement)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866128 Neighboring gene pseudouridine synthase 1 Neighboring gene unc-51 like autophagy activating kinase 1 Neighboring gene splicing factor SWAP Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
matrix metalloproteinase-17; LOW QUALITY PROTEIN: matrix metalloproteinase-17
XP_038292239.1
XP_038292240.1
XP_038315177.1
XP_038315178.1
XP_038367176.1
XP_038367177.1
XP_038430635.1
XP_038494829.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    1072479..1091195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436312.1XP_038292240.1  matrix metalloproteinase-17 isoform X2

    UniProtKB/TrEMBL
    A0A8C0P043, A0A8I3QR45
    Related
    ENSCAFP00845040188.1, ENSCAFT00845051242.1
    Conserved Domains (3) summary
    cd00094
    Location:331525
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:130292
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:42102
    PG_binding_1; Putative peptidoglycan binding domain
  2. XM_038436311.1XP_038292239.1  matrix metalloproteinase-17 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P165, A0A8I3PZ83
    Related
    ENSCAFP00845040142.1, ENSCAFT00845051184.1
    Conserved Domains (3) summary
    cd00094
    Location:331525
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:130292
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:42102
    PG_binding_1; Putative peptidoglycan binding domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    1009626..1028354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038511249.1XP_038367177.1  matrix metalloproteinase-17 isoform X2

    Conserved Domains (3) summary
    cd00094
    Location:333527
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:132294
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:44104
    PG_binding_1; Putative peptidoglycan binding domain
  2. XM_038511248.1XP_038367176.1  matrix metalloproteinase-17 isoform X1

    Conserved Domains (3) summary
    cd00094
    Location:333527
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:132294
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:44104
    PG_binding_1; Putative peptidoglycan binding domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    1106771..1124956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638901.1XP_038494829.1  LOW QUALITY PROTEIN: matrix metalloproteinase-17 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    1029400..1048084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038574707.1XP_038430635.1  matrix metalloproteinase-17 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KE66

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1054484..1073216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038459250.1XP_038315178.1  matrix metalloproteinase-17 isoform X2

    UniProtKB/TrEMBL
    A0A8C0P043, A0A8C0TCY3, A0A8P0T6Q9
    Conserved Domains (3) summary
    cd00094
    Location:333527
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:132294
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:44104
    PG_binding_1; Putative peptidoglycan binding domain
  2. XM_038459249.1XP_038315177.1  matrix metalloproteinase-17 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P165, A0A8C0TF58, A0A8P0N925
    Conserved Domains (3) summary
    cd00094
    Location:333527
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:132294
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:44104
    PG_binding_1; Putative peptidoglycan binding domain