DFFB DNA fragmentation factor subunit beta [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: DFFBprovided by VGNC
Official Full Name: DNA fragmentation factor subunit betaprovided by VGNC
Primary source: VGNC:VGNC:39910
See related: Ensembl:ENSCAFG00845020920
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	5	NC_051809.1 (58547681..58562856)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	5	NC_006587.4 (58350476..58365648)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	5	NC_049226.1 (58814557..58829729)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	5	NC_049265.1 (58555388..58570554)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	5	NC_049746.1 (58424285..58439461)

Chromosome 5 - NC_051809.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA endonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in apoptotic DNA fragmentation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA fragmentation factor subunit beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051809.1 Reference ROS_Cfam_1.0

Range

58547681..58562856

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038666500.1 → XP_038522428.1 DNA fragmentation factor subunit beta isoform X1

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:132 → 355

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038666502.1 → XP_038522430.1 DNA fragmentation factor subunit beta isoform X3

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:117 → 340

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038666501.1 → XP_038522429.1 DNA fragmentation factor subunit beta isoform X2

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:118 → 341

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038666503.1 → XP_038522431.1 DNA fragmentation factor subunit beta isoform X4

UniProtKB/TrEMBL

A0A8C0K919, A0A8C0QR60, A0A8I3P9N0, A0A8I3S216

Related

ENSCAFP00845028900.1, ENSCAFT00845036914.1

Conserved Domains (2) summary

pfam09230
Location:103 → 326

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049265.1 Alternate UMICH_Zoey_3.1

Range

58555388..58570554

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038476617.1 → XP_038332545.1 DNA fragmentation factor subunit beta isoform X1

Conserved Domains (2) summary

pfam09230
Location:132 → 355

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038476619.1 → XP_038332547.1 DNA fragmentation factor subunit beta isoform X3

Conserved Domains (2) summary

pfam09230
Location:117 → 340

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038476618.1 → XP_038332546.1 DNA fragmentation factor subunit beta isoform X2

Conserved Domains (2) summary

pfam09230
Location:118 → 341

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038476620.1 → XP_038332548.1 DNA fragmentation factor subunit beta isoform X4

Conserved Domains (2) summary

pfam09230
Location:103 → 326

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049746.1 Alternate UNSW_CanFamBas_1.0

Range

58424285..58439461

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038601914.1 → XP_038457842.1 DNA fragmentation factor subunit beta isoform X1

Conserved Domains (2) summary

pfam09230
Location:132 → 355

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038601916.1 → XP_038457844.1 DNA fragmentation factor subunit beta isoform X3

Conserved Domains (2) summary

pfam09230
Location:117 → 340

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038601915.1 → XP_038457843.1 DNA fragmentation factor subunit beta isoform X2

Conserved Domains (2) summary

pfam09230
Location:118 → 341

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038601917.1 → XP_038457845.1 DNA fragmentation factor subunit beta isoform X4

Conserved Domains (2) summary

pfam09230
Location:103 → 326

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049226.1 Alternate UU_Cfam_GSD_1.0

Range

58814557..58829729

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038537752.1 → XP_038393680.1 DNA fragmentation factor subunit beta isoform X1

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:132 → 355

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038537755.1 → XP_038393683.1 DNA fragmentation factor subunit beta isoform X3

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:117 → 340

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038537753.1 → XP_038393681.1 DNA fragmentation factor subunit beta isoform X2

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:118 → 341

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_038537756.1 → XP_038393684.1 DNA fragmentation factor subunit beta isoform X4

UniProtKB/TrEMBL

A0A8C0K919, A0A8C0QR60, A0A8I3P9N0, A0A8I3S216

Conserved Domains (2) summary

pfam09230
Location:103 → 326

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

58350476..58365648

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_022418970.2 → XP_022274678.1 DNA fragmentation factor subunit beta isoform X1

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:132 → 355

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_022418972.2 → XP_022274680.1 DNA fragmentation factor subunit beta isoform X3

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:117 → 340

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 97

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_014113878.3 → XP_013969353.1 DNA fragmentation factor subunit beta isoform X2

UniProtKB/TrEMBL

A0A8I3P9N0

Conserved Domains (2) summary

pfam09230
Location:118 → 341

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
XM_546743.6 → XP_546743.2 DNA fragmentation factor subunit beta isoform X4

UniProtKB/TrEMBL

A0A8C0K919, A0A8C0QR60, A0A8I3P9N0, A0A8I3S216

Conserved Domains (2) summary

pfam09230
Location:103 → 326

DFF40; DNA fragmentation factor 40 kDa

cl02541
Location:7 → 83

CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...