GATA3 GATA binding protein 3 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: GATA3provided by VGNC
Official Full Name: GATA binding protein 3provided by VGNC
Primary source: VGNC:VGNC:41123
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	2	NC_051806.1 (28443699..28464623, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	2	NC_006584.4 (25104703..25134953, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	2	NC_049223.1 (27112635..27142926, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	2	NC_049262.1 (25552826..25583058, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	2	NC_049743.1 (26396168..26425115, complement)

Chromosome 2 - NC_051806.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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General gene information

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Markers

GATA3 (e-PCR)
- UniSTS:506387

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell fate commitment	IEA Inferred from Electronic Annotation more info	PubMed
involved_in embryonic organ development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of epithelial cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LOW QUALITY PROTEIN: trans-acting T-cell-specific transcription factor GATA-3; trans-acting T-cell-specific transcription factor GATA-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051806.1 Reference ROS_Cfam_1.0

Range

28443699..28464623 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038660403.1 → XP_038516331.1 LOW QUALITY PROTEIN: trans-acting T-cell-specific transcription factor GATA-3 isoform X1

UniProtKB/TrEMBL

A0A8I3MCW5

Conserved Domains (1) summary

cd00202
Location:323 → 373

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

Alternate UMICH_Zoey_3.1

Genomic

NC_049262.1 Alternate UMICH_Zoey_3.1

Range

25552826..25583058 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038469403.1 → XP_038325331.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X2

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038469402.1 → XP_038325330.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X2

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038469405.1 → XP_038325333.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X3

Conserved Domains (1) summary

cd00202
Location:316 → 366

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038469404.1 → XP_038325332.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X2

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038469401.1 → XP_038325329.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X2

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049743.1 Alternate UNSW_CanFamBas_1.0

Range

26396168..26425115 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038594411.1 → XP_038450339.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X4

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038594410.1 → XP_038450338.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X4

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038594413.1 → XP_038450341.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X5

Conserved Domains (1) summary

cd00202
Location:316 → 366

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038594412.1 → XP_038450340.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X4

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038594409.1 → XP_038450337.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X4

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049223.1 Alternate UU_Cfam_GSD_1.0

Range

27112635..27142926 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038530158.1 → XP_038386086.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X6

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038530157.1 → XP_038386085.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X6

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038530161.1 → XP_038386089.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X7

Conserved Domains (1) summary

cd00202
Location:316 → 366

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038530160.1 → XP_038386088.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X6

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038530156.1 → XP_038386084.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X6

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

25104703..25134953 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_014122792.3 → XP_013978267.2 trans-acting T-cell-specific transcription factor GATA-3 isoform X8

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_005617157.4 → XP_005617214.2 trans-acting T-cell-specific transcription factor GATA-3 isoform X8

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_014122799.3 → XP_013978274.2 trans-acting T-cell-specific transcription factor GATA-3 isoform X9

Conserved Domains (1) summary

cd00202
Location:316 → 366

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_038457313.1 → XP_038313241.1 trans-acting T-cell-specific transcription factor GATA-3 isoform X8

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
XM_844060.4 → XP_849153.2 trans-acting T-cell-specific transcription factor GATA-3 isoform X8

UniProtKB/TrEMBL

A0A8C0JZ49, A0A8C0QA77, A0A8P0N7S5

Conserved Domains (1) summary

cd00202
Location:317 → 367

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C