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ARHGEF7 Rho guanine nucleotide exchange factor 7 [ Canis lupus familiaris (dog) ]

Gene ID: 485552, updated on 5-Mar-2024

Summary

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Official Symbol
ARHGEF7provided by VGNC
Official Full Name
Rho guanine nucleotide exchange factor 7provided by VGNC
Primary source
VGNC:VGNC:54920
See related
Ensembl:ENSCAFG00845021560
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
28
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 22 NC_051826.1 (59801684..59928168)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 22 NC_006604.4 (58888587..59015004)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 22 NC_049243.1 (59330969..59457416)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 22 NC_049282.1 (59303236..59429725)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 22 NC_049763.1 (59295788..59422676)

Chromosome 22 - NC_051826.1Genomic Context describing neighboring genes Neighboring gene sperm acrosome-associated protein 7-like Neighboring gene uncharacterized LOC119865239 Neighboring gene uncharacterized LOC119865238 Neighboring gene uncharacterized LOC102154815 Neighboring gene uncharacterized LOC111091720 Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene uncharacterized LOC111091719 Neighboring gene testis expressed 29 Neighboring gene SRY-box transcription factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 7; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051826.1 Reference ROS_Cfam_1.0

    Range
    59801684..59928168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038431480.1 → XP_038287408.1  rho guanine nucleotide exchange factor 7 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PEB0, A0A8P0TRF2
    Related
    ENSCAFP00845030182.1, ENSCAFT00845038554.1
    Conserved Domains (6) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  2. XM_038431477.1 → XP_038287405.1  rho guanine nucleotide exchange factor 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PFV3, A0A8C0QG04, A0A8C0QP77
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 859
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  3. XM_038431478.1 → XP_038287406.1  rho guanine nucleotide exchange factor 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L309, A0A8C0PK78, A0A8C0QAW7, A0A8I3S560
    Related
    ENSCAFP00845030026.1, ENSCAFT00845038352.1
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:714 → 800
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  4. XM_038431481.1 → XP_038287409.1  rho guanine nucleotide exchange factor 7 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QP77
    Related
    ENSCAFP00845030421.1, ENSCAFT00845038843.1
    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  5. XM_038431483.1 → XP_038287411.1  rho guanine nucleotide exchange factor 7 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QP77
    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  6. XM_038431479.1 → XP_038287407.1  rho guanine nucleotide exchange factor 7 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PFG5, A0A8C0QP77, A0A8I3PIX8
    Related
    ENSCAFP00845030524.1, ENSCAFT00845038974.1
    Conserved Domains (7) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:691 → 777
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:35 → 81
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cl00030
    Location:1 → 33
    CH_SF; calponin homology (CH) domain superfamily

  7. XM_038431482.1 → XP_038287410.1  rho guanine nucleotide exchange factor 7 isoform X6

    UniProtKB/TrEMBL
    A0A8I3S5G7, A0A8P0T9H3
    Related
    ENSCAFP00845030665.1, ENSCAFT00845039155.1
    Conserved Domains (4) summary
    cd00160
    Location:16 → 192
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:223 → 321
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:377 → 475
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:537 → 623
    betaPIX_CC; betaPIX coiled coil

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049282.1 Alternate UMICH_Zoey_3.1

    Range
    59303236..59429725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038506849.1 → XP_038362777.1  rho guanine nucleotide exchange factor 7 isoform X4

    Conserved Domains (6) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  2. XM_038506846.1 → XP_038362774.1  rho guanine nucleotide exchange factor 7 isoform X1

    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 859
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  3. XM_038506847.1 → XP_038362775.1  rho guanine nucleotide exchange factor 7 isoform X2

    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:714 → 800
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  4. XM_038506850.1 → XP_038362778.1  rho guanine nucleotide exchange factor 7 isoform X5

    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  5. XM_038506852.1 → XP_038362780.1  rho guanine nucleotide exchange factor 7 isoform X5

    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  6. XM_038506848.1 → XP_038362776.1  rho guanine nucleotide exchange factor 7 isoform X3

    Conserved Domains (7) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:691 → 777
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:35 → 81
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cl00030
    Location:1 → 33
    CH_SF; calponin homology (CH) domain superfamily

  7. XM_038506851.1 → XP_038362779.1  rho guanine nucleotide exchange factor 7 isoform X6

    Conserved Domains (4) summary
    cd00160
    Location:16 → 192
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:223 → 321
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:377 → 475
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:537 → 623
    betaPIX_CC; betaPIX coiled coil

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049763.1 Alternate UNSW_CanFamBas_1.0

    Range
    59295788..59422676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038634224.1 → XP_038490152.1  rho guanine nucleotide exchange factor 7 isoform X4

    Conserved Domains (6) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  2. XM_038634220.1 → XP_038490148.1  rho guanine nucleotide exchange factor 7 isoform X1

    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 859
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  3. XM_038634221.1 → XP_038490149.1  rho guanine nucleotide exchange factor 7 isoform X2

    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:714 → 800
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  4. XM_038634225.1 → XP_038490153.1  rho guanine nucleotide exchange factor 7 isoform X5

    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  5. XM_038634227.1 → XP_038490155.1  rho guanine nucleotide exchange factor 7 isoform X5

    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  6. XM_038634223.1 → XP_038490151.1  rho guanine nucleotide exchange factor 7 isoform X3

    Conserved Domains (7) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:691 → 777
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:35 → 81
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cl00030
    Location:1 → 33
    CH_SF; calponin homology (CH) domain superfamily

  7. XM_038634226.1 → XP_038490154.1  rho guanine nucleotide exchange factor 7 isoform X6

    Conserved Domains (4) summary
    cd00160
    Location:16 → 192
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:223 → 321
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:377 → 475
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:537 → 623
    betaPIX_CC; betaPIX coiled coil

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049243.1 Alternate UU_Cfam_GSD_1.0

    Range
    59330969..59457416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038570061.1 → XP_038425989.1  LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QG04, A0A8C0QP77

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006604.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    58888587..59015004
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038456755.1 → XP_038312683.1  rho guanine nucleotide exchange factor 7 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PEB0, A0A8P0TRF2
    Conserved Domains (6) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  2. XM_038456753.1 → XP_038312681.1  rho guanine nucleotide exchange factor 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PFV3, A0A8C0QG04, A0A8C0QP77
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 859
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  3. XM_038456754.1 → XP_038312682.1  rho guanine nucleotide exchange factor 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L309, A0A8C0PK78, A0A8C0QAW7, A0A8I3S560
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:714 → 800
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  4. XM_038456756.1 → XP_038312684.1  rho guanine nucleotide exchange factor 7 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QP77
    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  5. XM_038456757.1 → XP_038312685.1  rho guanine nucleotide exchange factor 7 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QP77
    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:616 → 702
    betaPIX_CC; betaPIX coiled coil

  6. XM_005634100.4 → XP_005634157.1  rho guanine nucleotide exchange factor 7 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PFG5, A0A8C0QP77, A0A8I3PIX8
    Conserved Domains (7) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:691 → 777
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:35 → 81
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cl00030
    Location:1 → 33
    CH_SF; calponin homology (CH) domain superfamily

  7. XM_005634103.4 → XP_005634160.1  rho guanine nucleotide exchange factor 7 isoform X6

    UniProtKB/TrEMBL
    A0A8I3S5G7, A0A8P0T9H3
    Conserved Domains (4) summary
    cd00160
    Location:16 → 192
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:223 → 321
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:377 → 475
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:537 → 623
    betaPIX_CC; betaPIX coiled coil
Nucleotide Protein
Heading Accession and Version

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