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POLR2A RNA polymerase II subunit A [ Canis lupus familiaris (dog) ]

Gene ID: 479483, updated on 5-Mar-2024

Summary

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Official Symbol
POLR2Aprovided by VGNC
Official Full Name
RNA polymerase II subunit Aprovided by VGNC
Primary source
VGNC:VGNC:44792
See related
Ensembl:ENSCAFG00845022622
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
29
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (32509534..32535275)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (32541944..32567696)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (32610752..32636501)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (32474744..32500516)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (32433445..32459212)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871844 Neighboring gene cholinergic receptor nicotinic beta 1 subunit Neighboring gene zinc finger and BTB domain containing 4 Neighboring gene solute carrier family 35 member G6 Neighboring gene uncharacterized LOC102153734 Neighboring gene ribosome biogenesis protein WDR12-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II, core complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA-directed RNA polymerase II subunit RPB1; LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1
Names
220 kDa DNA-directed RNA polymerase polypeptide A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
XP_038331429.1
XP_038392602.1
XP_038456803.1
XP_038521325.1
XP_857844.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    32509534..32535275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038665397.1 → XP_038521325.1  DNA-directed RNA polymerase II subunit RPB1

    UniProtKB/TrEMBL
    A0A8C0NBD0, A0A8C0QXL5, A0A8I3PKJ4
    Related
    ENSCAFP00845031290.1, ENSCAFT00845039960.1
    Conserved Domains (5) summary
    cd02584
    Location:1058 → 1476
    RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain
    smart01104
    Location:1491 → 1610
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    cd02733
    Location:19 → 876
    RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain
    pfam05109
    Location:1854 → 1959
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam04992
    Location:896 → 1079
    RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    32474744..32500516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475501.1 → XP_038331429.1  DNA-directed RNA polymerase II subunit RPB1

    Conserved Domains (5) summary
    cd02584
    Location:1058 → 1476
    RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain
    smart01104
    Location:1491 → 1610
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    cd02733
    Location:19 → 876
    RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain
    pfam05109
    Location:1854 → 1959
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam04992
    Location:896 → 1079
    RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    32433445..32459212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600875.1 → XP_038456803.1  LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    32610752..32636501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038536674.1 → XP_038392602.1  DNA-directed RNA polymerase II subunit RPB1

    UniProtKB/TrEMBL
    A0A8C0NBD0, A0A8C0QXL5, A0A8I3PKJ4
    Conserved Domains (5) summary
    cd02584
    Location:1058 → 1476
    RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain
    smart01104
    Location:1491 → 1610
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    cd02733
    Location:19 → 876
    RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain
    pfam05109
    Location:1854 → 1959
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam04992
    Location:896 → 1079
    RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    32541944..32567696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_852751.5 → XP_857844.4  DNA-directed RNA polymerase II subunit RPB1

    UniProtKB/TrEMBL
    A0A8C0NBD0, A0A8C0QXL5, A0A8I3PKJ4
    Conserved Domains (5) summary
    cd02584
    Location:1058 → 1476
    RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain
    smart01104
    Location:1491 → 1610
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    cd02733
    Location:19 → 876
    RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain
    pfam05109
    Location:1854 → 1959
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam04992
    Location:896 → 1079
    RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6
Nucleotide Protein Strain
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