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IL1A interleukin 1 alpha [ Pan troglodytes (chimpanzee) ]

Gene ID: 470485, updated on 29-Mar-2024

Summary

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Official Symbol
IL1Aprovided by VGNC
Official Full Name
interleukin 1 alphaprovided by VGNC
Primary source
VGNC:VGNC:1939
Locus tag
CK820_G0052785
See related
Ensembl:ENSPTRG00000012371
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2A
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (10486873..10496951)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (112002032..112012129, complement)

Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene interleukin 36 gamma Neighboring gene uncharacterized LOC112208185 Neighboring gene interleukin 1 beta Neighboring gene cytoskeleton associated protein 2 like Neighboring gene 5'-nucleotidase domain containing 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-1 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of immature T cell proliferation in thymus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-1 alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    10486873..10496951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_525866.4 → XP_525866.1  interleukin-1 alpha

    See identical proteins and their annotated locations for XP_525866.1

    UniProtKB/TrEMBL
    A0A2J8IVU7, A0A6D2XGP0, H2QIK5
    Related
    ENSPTRP00000021189.3
    Conserved Domains (2) summary
    smart00125
    Location:129 → 267
    IL1; Interleukin-1 homologues
    pfam02394
    Location:1 → 108
    IL1_propep; Interleukin-1 propeptide
Nucleotide Protein
Heading Accession and Version

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