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MAP3K7 mitogen-activated protein kinase kinase kinase 7 [ Pan troglodytes (chimpanzee) ]

Gene ID: 462888, updated on 29-Mar-2024

Summary

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Official Symbol
MAP3K7provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase kinase 7provided by VGNC
Primary source
VGNC:VGNC:7196
Locus tag
CK820_G0000741
See related
Ensembl:ENSPTRG00000018427
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 5 NC_072403.2 (102522450..102592957, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 6 NC_072404.1 (102520091..102593929, complement)

Chromosome 5 - NC_072403.2Genomic Context describing neighboring genes Neighboring gene BTB domain and CNC homolog 2 Neighboring gene uncharacterized LOC129144406 Neighboring gene uncharacterized LOC107975222 Neighboring gene uncharacterized LOC129144301 Neighboring gene uncharacterized LOC134810241 Neighboring gene uncharacterized LOC107975330

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase 7
XP_001160579.1
XP_003950941.1
XP_003950942.1
XP_003950943.1
XP_009449928.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    102522450..102592957 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009451653.5 → XP_009449928.1  mitogen-activated protein kinase kinase kinase 7 isoform X4

    See identical proteins and their annotated locations for XP_009449928.1

    Conserved Domains (1) summary
    cd14058
    Location:1 → 189
    STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

  2. XM_003950893.5 → XP_003950942.1  mitogen-activated protein kinase kinase kinase 7 isoform X5

    See identical proteins and their annotated locations for XP_003950942.1

    UniProtKB/TrEMBL
    A0A2J8PV40
    Conserved Domains (1) summary
    cd14058
    Location:42 → 292
    STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

  3. XM_003950892.5 → XP_003950941.1  mitogen-activated protein kinase kinase kinase 7 isoform X2

    See identical proteins and their annotated locations for XP_003950941.1

    UniProtKB/TrEMBL
    A0A2J8PV48, A0A6D2WF67, K7C324
    Related
    ENSPTRP00000087171.1
    Conserved Domains (1) summary
    cd14058
    Location:42 → 292
    STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

  4. XM_003950894.5 → XP_003950943.1  mitogen-activated protein kinase kinase kinase 7 isoform X3

    See identical proteins and their annotated locations for XP_003950943.1

    UniProtKB/TrEMBL
    A0A2I3SPY9, A0A2J8PV56, A0A6D2Y3C6
    Related
    ENSPTRP00000079100.1
    Conserved Domains (1) summary
    cd14058
    Location:42 → 292
    STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

  5. XM_001160579.7 → XP_001160579.1  mitogen-activated protein kinase kinase kinase 7 isoform X1

    See identical proteins and their annotated locations for XP_001160579.1

    UniProtKB/TrEMBL
    A0A2J8PV49, A0A6D2XZK4, H2RCY2
    Related
    ENSPTRP00000057993.1
    Conserved Domains (1) summary
    cd14058
    Location:42 → 292
    STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1
Nucleotide Protein
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