CAPN11 calpain 11 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CAPN11provided by VGNC
Official Full Name: calpain 11provided by VGNC
Primary source: VGNC:VGNC:11039
Locus tag: CK820_G0007296
See related: Ensembl:ENSPTRG00000018215
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: calpain-11
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	5	NC_072403.2 (50055524..50080446)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	6	NC_072404.1 (50055661..50080451)

Chromosome 5 - NC_072403.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

CAPN11_9225 (e-PCR)
- UniSTS:468314

D6S1650 (e-PCR)
- UniSTS:54171

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium-dependent cysteine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: calpain-11

NP_001267198.1

EC 3.4.22.17

XP_063667999.1

EC 3.4.22.17

XP_063668000.1

EC 3.4.22.17

XP_063668001.1

EC 3.4.22.17

XP_063668002.1

EC 3.4.22.17

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001280269.1 → NP_001267198.1 calpain-11

See identical proteins and their annotated locations for NP_001267198.1

Status: PROVISIONAL

Source sequence(s)

AK306445

UniProtKB/TrEMBL

A0A2I3SSG1, A0A2J8P0G3, A0A6D2WKJ6, G2HI81

Related

ENSPTRP00000058028.3, ENSPTRT00000066451.3

Conserved Domains (4) summary

cd00051
Location:578 → 628

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam00648
Location:43 → 339

Peptidase_C2; Calpain family cysteine protease

pfam01067
Location:353 → 507

Calpain_III; Calpain large subunit, domain III

cl08302
Location:609 → 664

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...