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CDK7 cyclin dependent kinase 7 [ Pan troglodytes (chimpanzee) ]

Gene ID: 462378, updated on 3-Apr-2024

Summary

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Official Symbol
CDK7provided by VGNC
Official Full Name
cyclin dependent kinase 7provided by VGNC
Primary source
VGNC:VGNC:11877
Locus tag
CK820_G0034228
See related
Ensembl:ENSPTRG00000016946
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (45373904..45416849, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (45789396..45834290, complement)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 2-like Neighboring gene coiled-coil domain containing 125 Neighboring gene alpha-ketoglutarate dehydrogenase subunit 4 Neighboring gene centromere protein H

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription factor TFIIH holo complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription factor TFIIK complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase 7
Names
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
XP_001160482.1
XP_009447339.1
XP_016808702.1
XP_016808703.1
XP_054541042.1
XP_054541043.1
XP_054541044.1
XP_063666487.1
XP_063666488.1
XP_063666489.1
XP_063666490.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    45373904..45416849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063810420.1 → XP_063666490.1  cyclin-dependent kinase 7 isoform X8

    UniProtKB/TrEMBL
    A0A2J8L108

  2. XM_001160482.7 → XP_001160482.1  cyclin-dependent kinase 7 isoform X1

    See identical proteins and their annotated locations for XP_001160482.1

    UniProtKB/TrEMBL
    A0A2I3S9X0, A0A2J8L0Z5, A0A2J8L109, A0A6D2WUK2, A0A6D2WVT0, H2QR08
    Related
    ENSPTRP00000073852.1
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  3. XM_063810419.1 → XP_063666489.1  cyclin-dependent kinase 7 isoform X8

    UniProtKB/TrEMBL
    A0A2J8L108

  4. XM_054685069.2 → XP_054541044.1  cyclin-dependent kinase 7 isoform X6

  5. XM_009449064.5 → XP_009447339.1  cyclin-dependent kinase 7 isoform X5

    See identical proteins and their annotated locations for XP_009447339.1

    Conserved Domains (1) summary
    cl21453
    Location:43 → 251
    PKc_like; Protein Kinases, catalytic domain

  6. XM_016953213.4 → XP_016808702.1  cyclin-dependent kinase 7 isoform X4

  7. XM_054685068.2 → XP_054541043.1  cyclin-dependent kinase 7 isoform X3

  8. XM_054685067.2 → XP_054541042.1  cyclin-dependent kinase 7 isoform X2

  9. XM_063810418.1 → XP_063666488.1  cyclin-dependent kinase 7 isoform X8

    UniProtKB/TrEMBL
    A0A2J8L108

  10. XM_063810417.1 → XP_063666487.1  cyclin-dependent kinase 7 isoform X8

    UniProtKB/TrEMBL
    A0A2J8L108

  11. XM_016953214.4 → XP_016808703.1  cyclin-dependent kinase 7 isoform X7

Nucleotide Protein
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