PDGFRA platelet derived growth factor receptor alpha [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PDGFRAprovided by VGNC
Official Full Name: platelet derived growth factor receptor alphaprovided by VGNC
Primary source: VGNC:VGNC:57070
See related: Ensembl:ENSPTRG00000016066
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (75556594..75627562, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (75556570..75627520, complement)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G43580 (e-PCR)
- UniSTS:95026

PDGFRA__1207 (e-PCR)
- UniSTS:277576

PDGFRA__v331 (e-PCR)
- UniSTS:277576

D4S1394 (e-PCR)
- UniSTS:79704

SHGC-85185 (e-PCR)
- UniSTS:104030

G34454 (e-PCR)
- UniSTS:2145

RH68733 (e-PCR)
- UniSTS:12701

GDB:626067 (e-PCR)
- UniSTS:158383

GDB:626070 (e-PCR)
- UniSTS:158384

SHGC-8069 (e-PCR)
- UniSTS:83678

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables platelet-derived growth factor alpha-receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables platelet-derived growth factor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in embryonic cranial skeleton morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in platelet-derived growth factor receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: platelet-derived growth factor receptor alpha

Names: platelet-derived growth factor receptor, alpha polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

75556594..75627562 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024356152.3 → XP_024211920.1 platelet-derived growth factor receptor alpha isoform X2

UniProtKB/TrEMBL

K7DT04

Conserved Domains (5) summary

cd04972
Location:415 → 497

Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC

cd05859
Location:313 → 413

Ig4_PDGFR; Fourth immunoglobulin (Ig)-like domain of platelet-derived growth factor receptor (PDGFR)

cd05861
Location:228 → 311

Ig_PDGFR-alphabeta; Immunoglobulin (Ig)-like domain of platelet-derived growth factor (PDGF) receptors (R), alpha (CD140a), and beta (CD140b)

cd05105
Location:555 → 956

PTKc_PDGFR_alpha; Catalytic domain of the Protein Tyrosine Kinase, Platelet Derived Growth Factor Receptor alpha

pfam13927
Location:28 → 100

Ig_3; Immunoglobulin domain
XM_016951727.4 → XP_016807216.1 platelet-derived growth factor receptor alpha isoform X2

UniProtKB/TrEMBL

K7DT04

Conserved Domains (5) summary

cd04972
Location:415 → 497

Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC

cd05859
Location:313 → 413

Ig4_PDGFR; Fourth immunoglobulin (Ig)-like domain of platelet-derived growth factor receptor (PDGFR)

cd05861
Location:228 → 311

Ig_PDGFR-alphabeta; Immunoglobulin (Ig)-like domain of platelet-derived growth factor (PDGF) receptors (R), alpha (CD140a), and beta (CD140b)

cd05105
Location:555 → 956

PTKc_PDGFR_alpha; Catalytic domain of the Protein Tyrosine Kinase, Platelet Derived Growth Factor Receptor alpha

pfam13927
Location:28 → 100

Ig_3; Immunoglobulin domain
XM_024356153.3 → XP_024211921.1 platelet-derived growth factor receptor alpha isoform X2

UniProtKB/TrEMBL

K7DT04

Conserved Domains (5) summary

cd04972
Location:415 → 497

Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC

cd05859
Location:313 → 413

Ig4_PDGFR; Fourth immunoglobulin (Ig)-like domain of platelet-derived growth factor receptor (PDGFR)

cd05861
Location:228 → 311

Ig_PDGFR-alphabeta; Immunoglobulin (Ig)-like domain of platelet-derived growth factor (PDGF) receptors (R), alpha (CD140a), and beta (CD140b)

cd05105
Location:555 → 956

PTKc_PDGFR_alpha; Catalytic domain of the Protein Tyrosine Kinase, Platelet Derived Growth Factor Receptor alpha

pfam13927
Location:28 → 100

Ig_3; Immunoglobulin domain
XM_016951726.4 → XP_016807215.1 platelet-derived growth factor receptor alpha isoform X1

UniProtKB/TrEMBL

H2QPH4

Related

ENSPTRP00000027635.4