PTGIS prostaglandin I2 synthase [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PTGISprovided by VGNC
Official Full Name: prostaglandin I2 synthaseprovided by VGNC
Primary source: VGNC:VGNC:14478
Locus tag: CK820_G0019886
See related: Ensembl:ENSPTRG00000013608
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	21	NC_072419.2 (55778958..55843349, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	20	NC_072418.1 (55834450..55898839, complement)

Chromosome 21 - NC_072419.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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General gene information

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Markers

WI-14359 (e-PCR)
- UniSTS:12544

RH79833 (e-PCR)
- UniSTS:88069

D8S2278 (e-PCR)
- UniSTS:473906

D8S2279 (e-PCR)
- UniSTS:473907

L18426 (e-PCR)
- UniSTS:34648

G54035 (e-PCR)
- UniSTS:109417

D1S1423 (e-PCR)
- UniSTS:149619

RH80030 (e-PCR)
- UniSTS:87680

GDB:315881 (e-PCR)
- UniSTS:156545

D3S1673 (e-PCR)
- UniSTS:148450

STS-D38145 (e-PCR)
- UniSTS:69875

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info	PubMed
enables prostaglandin-I synthase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in prostaglandin biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prostacyclin synthase

Names: prostaglandin I2 (prostacyclin) synthase

XP_016793607.1

EC 5.3.99.4

XP_063658658.1

EC 5.3.99.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

55778958..55843349 complement

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GenBank, FASTA, Sequence Viewer (Graphics)