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SOCS3 suppressor of cytokine signaling 3 [ Pan troglodytes (chimpanzee) ]

Gene ID: 454921, updated on 29-Mar-2024

Summary

Official Symbol
SOCS3provided by VGNC
Official Full Name
suppressor of cytokine signaling 3provided by VGNC
Primary source
VGNC:VGNC:9641
Locus tag
CK820_G0040970
See related
Ensembl:ENSPTRG00000052259
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 17
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (91370457..91374032, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (89554898..89557981, complement)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 235 Neighboring gene uncharacterized LOC101057283 Neighboring gene small nucleolar RNA SNORA30/SNORA37 family Neighboring gene phosphatidylglycerophosphate synthase 1 Neighboring gene dynein axonemal heavy chain 17

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
suppressor of cytokine signaling 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    91370457..91374032 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001157032.8XP_001157032.1  suppressor of cytokine signaling 3

    See identical proteins and their annotated locations for XP_001157032.1

    UniProtKB/TrEMBL
    A0A2J8K7W2, A0A6D2WCK4, H2QDZ6
    Related
    ENSPTRP00000092362.1
    Conserved Domains (2) summary
    cd10384
    Location:35135
    SH2_SOCS3; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03737
    Location:184225
    SOCS_SOCS3; SOCS (suppressors of cytokine signaling) box of SOCS3-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS3, like CIS1 and SOCS1, is involved in the ...