CSK C-terminal Src kinase [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CSKprovided by VGNC
Official Full Name: C-terminal Src kinaseprovided by VGNC
Primary source: VGNC:VGNC:14769
Locus tag: CK820_G0036616
See related: Ensembl:ENSPTRG00000007282
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	16	NC_072414.2 (66744611..66766135)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	15	NC_072413.1 (66720439..66740990)

Chromosome 16 - NC_072414.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

RH77839 (e-PCR)
- UniSTS:67364

CSK_3956 (e-PCR)
- UniSTS:462130

RH70899 (e-PCR)
- UniSTS:77652

RH69961 (e-PCR)
- UniSTS:26230

PMC193924P3 (e-PCR)
- UniSTS:271765

MARC_5011-5012:991939428:1 (e-PCR)
- UniSTS:231136

MARC_5011-5012:996690037:1 (e-PCR)
- UniSTS:231136

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables non-membrane spanning protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adherens junction organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of Fc receptor mediated stimulatory signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tyrosine-protein kinase CSK

Names: CSK, non-receptor tyrosine kinase; c-src tyrosine kinase

XP_016782687.1

EC 2.7.10.2

XP_063650273.1

EC 2.7.10.2

XP_063650274.1

EC 2.7.10.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

66744611..66766135

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063794204.1 → XP_063650274.1 tyrosine-protein kinase CSK

UniProtKB/TrEMBL

A0A2J8KRV3, A0A6D2Y6P4, H2Q9T1, K7AWV1
XM_016927198.3 → XP_016782687.1 tyrosine-protein kinase CSK

UniProtKB/TrEMBL

A0A2J8KRV3, A0A6D2Y6P4, H2Q9T1, K7AWV1

Related

ENSPTRP00000012464.4

Conserved Domains (3) summary

cd05082
Location:188 → 443

PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase

cd09937
Location:78 → 175

SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)

cd11769
Location:11 → 67

SH3_CSK; Src Homology 3 domain of C-terminal Src kinase
XM_063794203.1 → XP_063650273.1 tyrosine-protein kinase CSK

UniProtKB/TrEMBL

A0A2J8KRV3, A0A6D2Y6P4, H2Q9T1, K7AWV1