GNAO1 G protein subunit alpha o1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: GNAO1provided by VGNC
Official Full Name: G protein subunit alpha o1provided by VGNC
Primary source: VGNC:VGNC:13710
Locus tag: CK820_G0016648
See related: Ensembl:ENSPTRG00000008129
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	18	NC_072416.2 (54193219..54363279)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	16	NC_072414.1 (54193142..54367518)

Chromosome 18 - NC_072416.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

D16S434E (e-PCR)
- UniSTS:2821

D16S408 (e-PCR), detects polymorphism
- UniSTS:19980

D16S2786 (e-PCR)
- UniSTS:153356

SHGC-152262 (e-PCR)
- UniSTS:177450

RH71386 (e-PCR)
- UniSTS:29529

SHGC-106383 (e-PCR)
- UniSTS:169830

SHGC-79158 (e-PCR)
- UniSTS:95856

D16S736 (e-PCR)
- UniSTS:1652

SHGC-151028 (e-PCR)
- UniSTS:173192

SHGC-151169 (e-PCR)
- UniSTS:173454

D16S317 (e-PCR)
- UniSTS:147095

D16S408 (e-PCR), detects polymorphism
- UniSTS:24999

RH68394 (e-PCR)
- UniSTS:36522

D16S3140 (e-PCR)
- UniSTS:60588

D16S2698 (e-PCR)
- UniSTS:153268

D16S2699 (e-PCR)
- UniSTS:153269

G10169 (e-PCR)
- UniSTS:61393

D16S434E (e-PCR)
- UniSTS:147420

PMC19731P1 (e-PCR)
- UniSTS:271857

D16S434E (e-PCR)
- UniSTS:9726

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled serotonin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables G-protein beta/gamma-subunit complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables corticotropin-releasing hormone receptor 1 binding	IEA Inferred from Electronic Annotation more info	PubMed
enables mu-type opioid receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in dopamine receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of heterotrimeric G-protein complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanine nucleotide-binding protein G(o) subunit alpha

Names: G protein alpha activating activity polypeptide O; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; guanine nucleotide-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072416.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

54193219..54363279

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063797137.1 → XP_063653207.1 guanine nucleotide-binding protein G(o) subunit alpha isoform X3
XM_510976.9 → XP_510976.3 guanine nucleotide-binding protein G(o) subunit alpha isoform X1

See identical proteins and their annotated locations for XP_510976.3

UniProtKB/TrEMBL

A0A2J8MWP8, A0A6D2XXA2, H2QB45

Related

ENSPTRP00000013873.5

Conserved Domains (1) summary

cd00066
Location:34 → 348

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_009430843.4 → XP_009429118.1 guanine nucleotide-binding protein G(o) subunit alpha isoform X2

See identical proteins and their annotated locations for XP_009429118.1

UniProtKB/TrEMBL

A0A2I3TFM8, A0A2J8MWL6, A0A6D2XQ89

Related

ENSPTRP00000088044.1

Conserved Domains (1) summary

cd00066
Location:34 → 348

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_063797136.1 → XP_063653206.1 guanine nucleotide-binding protein G(o) subunit alpha isoform X3
XM_063797138.1 → XP_063653208.1 guanine nucleotide-binding protein G(o) subunit alpha isoform X4