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CYP51A1 cytochrome P450 family 51 subfamily A member 1 [ Gallus gallus (chicken) ]

Gene ID: 420548, updated on 5-Mar-2024

Summary

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Symbol
CYP51A1provided by CGNC
Full Name
cytochrome P450 family 51 subfamily A member 1provided by CGNC
Primary source
CGNC:7119
See related
Ensembl:ENSGALG00010005267
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CYP51
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (22397446..22416151, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (22428414..22447112, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417800 Neighboring gene frizzled class receptor 1 Neighboring gene A-kinase anchoring protein 9 Neighboring gene KRIT1, ankyrin repeat containing Neighboring gene ankyrin repeat and IBR domain containing 1 Neighboring gene uncharacterized LOC107052573

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning of chicken lanosterol 14alpha-demethylase (CYP51) cDNA: discovery of a testis-specific CYP51 transcript. Kojima M, et al. Comp Biochem Physiol A Mol Integr Physiol, 2006 Nov. PMID 16945562
  2. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. International Chicken Genome Sequencing Consortium. Nature, 2004 Dec 9. PMID 15592404

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lanosterol 14-alpha demethylase; leucine-rich repeat and death domain-containing protein 1
Names
cytochrome P450, family 51, subfamily A, polypeptide 1
lanosterol 14-demethylase
XP_015136877.2
XP_040521675.1
XP_040521676.1
XP_040521678.1
XP_040549439.1
XP_046790322.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    22397446..22416151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046934366.1 → XP_046790322.1  leucine-rich repeat and death domain-containing protein 1 isoform X3

  2. XM_015281391.4 → XP_015136877.2  lanosterol 14-alpha demethylase isoform X1

    UniProtKB/TrEMBL
    Q0KKP4
    Related
    ENSGALP00010007038.1, ENSGALT00010012474.1
    Conserved Domains (1) summary
    COG2124
    Location:54 → 473
    CypX; Cytochrome P450 [Secondary metabolites biosynthesis, transport and catabolism, Defense mechanisms]

  3. XM_040693505.2 → XP_040549439.1  leucine-rich repeat and death domain-containing protein 1 isoform X2

    Conserved Domains (2) summary
    PLN03150
    Location:1 → 81
    PLN03150; hypothetical protein; Provisional
    sd00031
    Location:11 → 33
    LRR_1; leucine-rich repeat [structural motif]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    22428414..22447112 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040665744.1 → XP_040521678.1  leucine-rich repeat and death domain-containing protein 1 isoform X3

    Conserved Domains (4) summary
    PLN03150
    Location:663 → 753
    PLN03150; hypothetical protein; Provisional
    PLN00113
    Location:168 → 670
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG2124
    Location:845 → 1264
    CypX; Cytochrome P450 [Secondary metabolites biosynthesis, transport and catabolism, Defense mechanisms]
    sd00033
    Location:381 → 403
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_040665741.2 → XP_040521675.1  lanosterol 14-alpha demethylase isoform X1

    UniProtKB/TrEMBL
    Q0KKP4

  3. XM_040665742.2 → XP_040521676.1  leucine-rich repeat and death domain-containing protein 1 isoform X2

    Conserved Domains (2) summary
    PLN03150
    Location:1 → 81
    PLN03150; hypothetical protein; Provisional
    sd00031
    Location:11 → 33
    LRR_1; leucine-rich repeat [structural motif]

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001048077.1: Suppressed sequence

    Description
    NM_001048077.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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