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PAK1 p21 (RAC1) activated kinase 1 [ Gallus gallus (chicken) ]

Gene ID: 419083, updated on 5-Mar-2024

Summary

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Symbol
PAK1provided by CGNC
Full Name
p21 (RAC1) activated kinase 1provided by CGNC
Primary source
CGNC:432
See related
Ensembl:ENSGALG00010002102
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (192921986..192989287)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (192991543..193058789)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-12215 Neighboring gene chloride nucleotide-sensitive channel 1A Neighboring gene uncharacterized LOC107055756 Neighboring gene aquaporin 11 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene myosin VIIA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 1
Names
p21 protein (Cdc42/Rac)-activated kinase 1
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
NP_001155844.1
XP_015136339.1
XP_015136341.1
XP_040556531.1
XP_040556538.1
XP_040556552.1
XP_040556563.1
XP_040556573.1
XP_040556578.1
XP_040556582.1
XP_040556587.1
XP_040556594.1
XP_040556635.1
XP_040556642.1
XP_046764362.1
XP_046764363.1
XP_046764364.1
XP_046764365.1
XP_046764366.1
XP_046764367.1
XP_046764368.1
XP_046764369.1
XP_046764370.1
XP_046764371.1
XP_046764372.1
XP_046764373.1
XP_046764374.1
XP_046764375.1
XP_046764376.1
XP_046764377.1
XP_046764378.1
XP_046764379.1
XP_046764380.1
XP_046764381.1
XP_046764382.1
XP_046764383.1
XP_046798313.1
XP_046798329.1
XP_046798332.1
XP_046798334.1
XP_046798337.1
XP_046798339.1
XP_046798341.1
XP_046798343.1
XP_046798344.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162372.5 → NP_001155844.1  serine/threonine-protein kinase PAK 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000028
    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    192921986..192989287
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040700653.2 → XP_040556587.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  2. XM_040700701.2 → XP_040556635.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  3. XM_046942373.1 → XP_046798329.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  4. XM_046942383.1 → XP_046798339.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  5. XM_046942385.1 → XP_046798341.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  6. XM_046942378.1 → XP_046798334.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  7. XM_046942357.1 → XP_046798313.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  8. XM_046942381.1 → XP_046798337.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  9. XM_040700708.2 → XP_040556642.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  10. XM_046942376.1 → XP_046798332.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  11. XM_040700648.2 → XP_040556582.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  12. XM_040700618.2 → XP_040556552.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  13. XM_040700629.2 → XP_040556563.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  14. XM_040700604.2 → XP_040556538.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  15. XM_040700644.2 → XP_040556578.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  16. XM_040700597.2 → XP_040556531.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Related
    ENSGALP00010002842.1, ENSGALT00010004716.1
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  17. XM_040700639.2 → XP_040556573.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  18. XM_046942387.1 → XP_046798343.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  19. XM_015280853.4 → XP_015136339.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  20. XM_015280855.4 → XP_015136341.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  21. XM_046942388.1 → XP_046798344.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  22. XM_040700660.2 → XP_040556594.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    192991543..193058789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908424.1 → XP_046764380.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  2. XM_046908427.1 → XP_046764383.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  3. XM_046908417.1 → XP_046764373.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  4. XM_046908422.1 → XP_046764378.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  5. XM_046908423.1 → XP_046764379.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  6. XM_046908419.1 → XP_046764375.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  7. XM_046908413.1 → XP_046764369.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  8. XM_046908420.1 → XP_046764376.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  9. XM_046908416.1 → XP_046764372.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  10. XM_046908418.1 → XP_046764374.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  11. XM_046908415.1 → XP_046764371.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  12. XM_046908410.1 → XP_046764366.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  13. XM_046908411.1 → XP_046764367.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  14. XM_046908408.1 → XP_046764364.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  15. XM_046908414.1 → XP_046764370.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  16. XM_046908409.1 → XP_046764365.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  17. XM_046908412.1 → XP_046764368.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  18. XM_046908425.1 → XP_046764381.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  19. XM_046908406.1 → XP_046764362.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  20. XM_046908407.1 → XP_046764363.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  21. XM_046908426.1 → XP_046764382.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6

  22. XM_046908421.1 → XP_046764377.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    E1C3P6
Nucleotide Protein Strain
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