ppp2r5d protein phosphatase 2, regulatory subunit B', delta [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ppp2r5dprovided by ZNC
Official Full Name: protein phosphatase 2, regulatory subunit B', deltaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2568
See related: Ensembl:ENSDARG00000014428 AllianceGenome:ZFIN:ZDB-GENE-040426-2568
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73160; zgc:77529
Summary: Predicted to enable protein phosphatase activator activity. Predicted to be involved in protein dephosphorylation. Predicted to act upstream of or within signal transduction. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 35. Orthologous to human PPP2R5D (protein phosphatase 2 regulatory subunit B'delta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (4232568..4303614, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (4104072..4175118, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

fd48e06.y1 (e-PCR)
- UniSTS:195524

fc78b12.y1 (e-PCR)
- UniSTS:194514

fd23a11.x1 (e-PCR)
- UniSTS:195302

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein phosphatase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase type 2A complex	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase type 2A complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213318.1 → NP_998483.1 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

See identical proteins and their annotated locations for NP_998483.1

Status: PROVISIONAL

Source sequence(s)

BC067382

UniProtKB/TrEMBL

Q6NWX4

Related

ENSDARP00000113159.2, ENSDART00000136262.3

Conserved Domains (2) summary

PLN00122
Location:405 → 507

PLN00122; serine/threonine protein phosphatase 2A; Provisional

pfam01603
Location:97 → 500

B56; Protein phosphatase 2A regulatory B subunit (B56 family)