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UCP1 uncoupling protein 1 [ Canis lupus familiaris (dog) ]

Gene ID: 403574, updated on 5-Mar-2024

Summary

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Gene symbol
UCP1
Gene description
uncoupling protein 1
See related
Ensembl:ENSCAFG00845020627
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (2346071..2354913)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (2528227..2536537)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (3000436..3008747)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (2283269..2291546)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (2644470..2652732)

Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091043 Neighboring gene TBC1 domain family member 9 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106560034 Neighboring gene ELMO domain containing 2 Neighboring gene MGAT4 family member D Neighboring gene uncharacterized LOC119864430

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of uncoupling protein 1 in the anti-obesity effect of beta3-adrenergic agonist in the dog. Omachi A, et al. Res Vet Sci, 2008 Oct. PMID 18406437
  2. Canine mitochondrial uncoupling proteins: structure and mRNA expression of three isoforms in adult beagles. Ishioka K, et al. Comp Biochem Physiol B Biochem Mol Biol, 2002 Mar. PMID 11959030

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidative phosphorylation uncoupler activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adaptive thermogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrial transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrial transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cold IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitochondrial brown fat uncoupling protein 1
Names
UCP 1
solute carrier family 25 member 7
thermogenin
uncoupling protein 1 UCP1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003046.1 → NP_001003046.1  mitochondrial brown fat uncoupling protein 1

    See identical proteins and their annotated locations for NP_001003046.1

    Status: PROVISIONAL

    Source sequence(s)
    AB046106
    UniProtKB/Swiss-Prot
    Q9GMZ1
    Conserved Domains (2) summary
    PTZ00169
    Location:33 → 299
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:114 → 207
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051823.1 Reference ROS_Cfam_1.0

    Range
    2346071..2354913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038425559.1 → XP_038281487.1  mitochondrial brown fat uncoupling protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0S0M6, A0A8I3S4I6
    Related
    ENSCAFP00845028509.1, ENSCAFT00845036422.1
    Conserved Domains (1) summary
    pfam00153
    Location:114 → 207
    Mito_carr; Mitochondrial carrier protein

  2. XM_038425558.1 → XP_038281486.1  mitochondrial brown fat uncoupling protein 1 isoform X1

    Conserved Domains (1) summary
    pfam00153
    Location:113 → 206
    Mito_carr; Mitochondrial carrier protein

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049279.1 Alternate UMICH_Zoey_3.1

    Range
    2283269..2291546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

    Range
    2644470..2652732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

    Range
    3000436..3008747
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    2528227..2536537
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GMZ1.1 GenPept UniProtKB/Swiss-Prot:Q9GMZ1

Gene LinkOut

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