U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ITGA6 integrin subunit alpha 6 [ Gallus gallus (chicken) ]

Gene ID: 396226, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Symbol
ITGA6provided by CGNC
Full Name
integrin subunit alpha 6provided by CGNC
Primary source
CGNC:7117
See related
Ensembl:ENSGALG00010021931
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 7
Exon count:
30
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (17336775..17455782, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (17255299..17374301, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1 regulatory subunit 9 like Neighboring gene uncharacterized LOC101748000 Neighboring gene uncharacterized LOC121113411 Neighboring gene pyruvate dehydrogenase kinase 1 Neighboring gene distal-less homeobox 2 Neighboring gene distal-less homeobox 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Function and spatial distribution in developing chick retina of the laminin receptor alpha 6 beta 1 and its isoforms. de Curtis I, et al. Development, 1993 Jun. PMID 8223267, Free PMC Article
  2. Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation. de Curtis I, et al. J Cell Biol, 1991 Apr. PMID 1826298, Free PMC Article
  3. Cranial neural crest recycle surface integrins in a substratum-dependent manner to promote rapid motility. Strachan LR, et al. J Cell Biol, 2004 Nov 8. PMID 15520227, Free PMC Article
  4. Differential expression of distinct members of Rho family GTP-binding proteins during neuronal development: identification of Rac1B, a new neural-specific member of the family. Malosio ML, et al. J Neurosci, 1997 Sep 1. PMID 9254684, Free PMC Article
  5. α6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation. Basu S, et al. J Biol Chem, 2014 Feb 14. PMID 24381169, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leukocyte migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
integrin alpha-6
Names
VLA-6
integrin alpha 6 subunit
integrin, alpha 6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205289.2 → NP_990620.2  integrin alpha-6 precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000236
    UniProtKB/Swiss-Prot
    P26007
    UniProtKB/TrEMBL
    A0A8V0ZFQ9
    Related
    ENSGALP00010032139.1, ENSGALT00010053327.1
    Conserved Domains (1) summary
    smart00191
    Location:367 → 419
    Int_alpha; Integrin alpha (beta-propellor repeats)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    17336775..17455782 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046943494.1 → XP_046799450.1  integrin alpha-6 isoform X2

    Related
    ENSGALP00010032186.1, ENSGALT00010053394.1

  2. XM_015289643.4 → XP_015145129.3  integrin alpha-6 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZTM8
    Conserved Domains (1) summary
    smart00191
    Location:267 → 319
    Int_alpha; Integrin alpha (beta-propellor repeats)

  3. XM_015289641.4 → XP_015145127.3  integrin alpha-6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZN77
    Related
    ENSGALP00010032173.1, ENSGALT00010053373.1
    Conserved Domains (1) summary
    smart00191
    Location:367 → 419
    Int_alpha; Integrin alpha (beta-propellor repeats)

  4. XM_046943495.1 → XP_046799451.1  integrin alpha-6 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZFS0
    Related
    ENSGALP00010032149.1, ENSGALT00010053343.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    17255299..17374301 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921143.1 → XP_046777099.1  integrin alpha-6 isoform X2

  2. XM_046921144.1 → XP_046777100.1  integrin alpha-6 isoform X3

  3. XM_046921142.1 → XP_046777098.1  integrin alpha-6 isoform X1

  4. XM_046921145.1 → XP_046777101.1  integrin alpha-6 isoform X4

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26007.1 GenPept UniProtKB/Swiss-Prot:P26007

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.