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pgm1 phosphoglucomutase 1 [ Danio rerio (zebrafish) ]

Gene ID: 394000, updated on 27-Mar-2024

Summary

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Official Symbol
pgm1provided by ZNC
Official Full Name
phosphoglucomutase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1245
See related
Ensembl:ENSDARG00000013561 AllianceGenome:ZFIN:ZDB-GENE-040426-1245
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63718
Summary
Predicted to enable phosphoglucomutase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to act upstream of or within glucose metabolic process. Predicted to be active in cytosol. Is expressed in central nervous system; digestive system; myotome; notochord; and yolk syncytial layer. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Orthologous to human PGM1 (phosphoglucomutase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (32010183..32025200, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (32023269..32038286, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene cache domain containing 1 Neighboring gene uncharacterized LOC110439871 Neighboring gene receptor tyrosine kinase-like orphan receptor 1 Neighboring gene EF-hand calcium binding domain 7 Neighboring gene integrin subunit beta 3 binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The evolutionary fate of alternatively spliced homologous exons after gene duplication. Abascal F, et al. Genome Biol Evol, 2015 Apr 29. PMID 25931610, Free PMC Article
  2. The toxic effect of triclosan and methyl-triclosan on biological pathways revealed by metabolomics and gene expression in zebrafish embryos. Fu J, et al. Ecotoxicol Environ Saf, 2020 Feb. PMID 31830605
  3. Scrambled eggs: Proteomic portraits and novel biomarkers of egg quality in zebrafish (Danio rerio). Yilmaz O, et al. PLoS One, 2017. PMID 29145436, Free PMC Article
  4. Proteomic analysis of zebrafish (Danio rerio) infected with infectious spleen and kidney necrosis virus. Xiong XP, et al. Dev Comp Immunol, 2011 Apr. PMID 21075138
  5. Proteomic analysis of anatoxin-a acute toxicity in zebrafish reveals gender specific responses and additional mechanisms of cell stress. Carneiro M, et al. Ecotoxicol Environ Saf, 2015 Oct. PMID 26046835

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC63718

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables intramolecular phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphoglucomutase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphoglucomutase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within organic substance metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
phosphoglucomutase-1
NP_957319.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201025.1 → NP_957319.1  phosphoglucomutase-1

    See identical proteins and their annotated locations for NP_957319.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055219
    UniProtKB/TrEMBL
    Q7SXW7
    Related
    ENSDARP00000006510.7, ENSDART00000006417.8
    Conserved Domains (2) summary
    cd03085
    Location:5 → 561
    PGM1; Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction, ...
    PLN02307
    Location:1 → 561
    PLN02307; phosphoglucomutase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    32010183..32025200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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