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rpa3 replication protein A3 [ Danio rerio (zebrafish) ]

Gene ID: 393196, updated on 27-Mar-2024

Summary

Official Symbol
rpa3provided by ZNC
Official Full Name
replication protein A3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-977
See related
Ensembl:ENSDARG00000002613 AllianceGenome:ZFIN:ZDB-GENE-040426-977
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56310; zgc:86697; im:6908405
Summary
Predicted to enable damaged DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in DNA repair and DNA replication. Predicted to act upstream of or within DNA recombination and DNA repair. Predicted to be located in nucleus. Predicted to be part of DNA replication factor A complex. Predicted to be active in site of double-strand break. Is expressed in several structures, including eye; immature eye; neural tube; pectoral fin musculature; and vasculature. Orthologous to human RPA3 (replication protein A3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (25465063..25467089)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (25880840..25882866)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene glucocorticoid induced 1a Neighboring gene UBAP1-MVB12-associated (UMA) domain containing 1 Neighboring gene collagen, type XXVIII, alpha 1a Neighboring gene core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Clone Names

  • MGC56310

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables damaged DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA recombination IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in base-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mismatch repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nucleotide-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of DNA replication factor A complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
is_active_in site of double-strand break IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
replication protein A 14 kDa subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200227.1NP_956521.1  replication protein A 14 kDa subunit

    See identical proteins and their annotated locations for NP_956521.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046064
    UniProtKB/TrEMBL
    Q7ZUZ6
    Related
    ENSDARP00000015592.4, ENSDART00000018553.5
    Conserved Domains (1) summary
    pfam08661
    Location:6113
    Rep_fac-A_3; Replication factor A protein 3

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    25465063..25467089
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)