eIF1 eukaryotic translation initiation factor 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: eIF1provided by FlyBase
Official Full Name: eukaryotic translation initiation factor 1provided by FlyBase
Primary source: FLYBASE:FBgn0035423
Locus tag: Dmel_CG17737
See related: AllianceGenome:FB:FBgn0035423
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:Posey272; BcDNA:RE14985; CG17737; dEIF1; Dmel\CG17737; EIF1
Summary: Predicted to enable ribosomal small subunit binding activity and translation initiation factor activity. Involved in cellular response to hypoxia. Predicted to be part of eukaryotic 43S preinitiation complex and multi-eIF complex. Is expressed in organism. Orthologous to several human genes including EIF1 (eukaryotic translation initiation factor 1). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (3223341..3224650)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (3223341..3224650)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribosomal small subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in cellular response to hypoxia	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in formation of translation preinitiation complex	ISS Inferred from Sequence or Structural Similarity more info
involved_in translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of eukaryotic 43S preinitiation complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic 43S preinitiation complex	ISS Inferred from Sequence or Structural Similarity more info
part_of multi-eIF complex	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain