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gtf-2H1 BSD domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176838, updated on 23-Nov-2023

Summary

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Gene symbol
gtf-2H1
Gene description
BSD domain-containing protein
Primary source
WormBase:WBGene00019821
Locus tag
CELE_R02D3.3
See related
AllianceGenome:WB:WBGene00019821
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in nucleic acid metabolic process and phosphorylation of RNA polymerase II C-terminal domain. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Orthologous to human GTF2H1 (general transcription factor IIH subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (225439..231773, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Phospholipid/glycerol acyltransferase domain-containing protein Neighboring gene Thioredoxin domain-containing protein Neighboring gene Protein asunder Neighboring gene EOG090X08PK

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcription mechanisms. Blackwell TK, et al. WormBook, 2006 Sep 5. PMID 18050436, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIIH core complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIIH core complex IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIIH holo complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BSD domain-containing protein
NP_001368352.1
  • Confirmed by transcript evidence
NP_499880.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    225439..231773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067479.6 → NP_499880.3  BSD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499880.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44499
    Conserved Domains (3) summary
    smart00751
    Location:118 → 174
    BSD; domain in transcription factors and synapse-associated proteins
    cd13229
    Location:8 → 110
    PH_TFIIH; Transcription Factor II H (TFIIH) Pleckstrin homology (PH) domain
    pfam03909
    Location:199 → 247
    BSD; BSD domain

  2. NM_001379998.1 → NP_001368352.1  BSD domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PCA7
Nucleotide Protein
Heading Accession and Version

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