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CACNA1S calcium voltage-gated channel subunit alpha1 S [ Bos taurus (cattle) ]

Gene ID: 100337204, updated on 3-Apr-2024

Summary

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Official Symbol
CACNA1Sprovided by VGNC
Official Full Name
calcium voltage-gated channel subunit alpha1 Sprovided by VGNC
Primary source
VGNC:VGNC:59326
See related
Ensembl:ENSBTAG00000047491
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
caV1.1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
45
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (79601791..79658538, complement)

Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene maestro heat-like repeat family member 5 Neighboring gene kinesin family member 21B Neighboring gene achaete-scute family bHLH transcription factor 5 Neighboring gene transmembrane protein 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Adrenal medulla calcium channel population is not conserved in bovine chromaffin cells in culture. Benavides A, et al. Neuroscience, 2004. PMID 15450357
  2. Greater diversity than previously thought of chromaffin cell Ca2+ channels, derived from mRNA identification studies. García-Palomero E, et al. FEBS Lett, 2000 Sep 22. PMID 11007970
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables high voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
voltage-dependent L-type calcium channel subunit alpha-1S
Names
calcium channel, voltage-dependent, L type, alpha 1S subunit
voltage-gated calcium channel alpha 1S subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    79601791..79658538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024976575.2 → XP_024832343.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform X2

    UniProtKB/TrEMBL
    G3MZ07
    Related
    ENSBTAP00000056589.3, ENSBTAT00000065568.3
    Conserved Domains (4) summary
    pfam00520
    Location:1117 → 1373
    Ion_trans; Ion transport protein
    pfam08763
    Location:1446 → 1517
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam16905
    Location:1374 → 1444
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    cl27975
    Location:1596 → 1762
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)

  2. XM_024976574.2 → XP_024832342.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform X1

    UniProtKB/TrEMBL
    G3MZ07
    Related
    ENSBTAP00000054797.3, ENSBTAT00000065901.3
    Conserved Domains (4) summary
    pfam00520
    Location:1117 → 1392
    Ion_trans; Ion transport protein
    pfam08763
    Location:1465 → 1536
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam16905
    Location:1393 → 1463
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    cl27975
    Location:1615 → 1781
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)

  3. XM_059875843.1 → XP_059731826.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform X3

Nucleotide Protein Strain
Heading Accession and Version

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