Protein Information

General Information of the Protein

Protein ID	PT00819
Protein Name	5-hydroxytryptamine receptor 1A
Secondarily Protein Name	G-21 Serotonin receptor 1A
Gene Name	HTR1A
Secondarily Gene Name	ADRB2RL1 ADRBRL1
Sequence	MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Small molecule receptor (family A GPCR) > Monoamine receptor > Serotonin receptor
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli. Show/Hide
Uniprot ID	Primary ID: P08908 Secondarily ID: Q6LAE7 Show/Hide
Ensembl ID	ENSG00000178394
HGNC ID	HGNC:5286
Subcellular Location	Cell membrane Cell projection Dendrite

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000011 , CHO

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0067873 Compound Info	4-methyl-2-[4-(4-pyridin-2-ylpiperazin-1-yl)butyl]-1,2,4-triazine-3,5-dione Show/Hide	C17H24N6O2	1
1	EC50 = 0.08 nM Bioactivity Info	TI LI LO TS
CP0067876 Compound Info	CAS_0 Show/Hide	C19H27N5O3	1
1	EC50 = 0.1 nM Bioactivity Info	TI LI LO TS
CP0067872 Compound Info	2-[4-[4-(6-fluoropyridin-2-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C17H23FN6O2	1
1	EC50 = 0.2 nM Bioactivity Info	TI LI LO TS
CP0418985 Compound Info	4-methyl-2-[4-(4-phenylpiperazin-1-yl)butyl]-1,2,4-triazine-3,5-dione Show/Hide	C18H25N5O2	2
1	EC50 = 0.3 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.15 nM Bioactivity Info	TI LI LO TS
CP0376586 Compound Info	1-[4-(3-methoxyphenyl)cyclohexyl]-4-pyridin-2-ylpiperazine Show/Hide	C22H29N3O	2
1	EC50 = 0.3236 nM Bioactivity Info	TI LI LO TS
2	EC50 = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0448258 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(5-fluoro-2-methoxyphenoxy)ethyl]propan-1-amine Show/Hide	C20H22F2N2O2	3
1	EC50 = 0.34 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4.7 nM Bioactivity Info	TI LI LO TS
3	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0038828 Compound Info	1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine Show/Hide	C23H31N3O	1
1	EC50 = 0.7762 nM Bioactivity Info	TI LI LO TS
CP0268138 Compound Info	2-[4-[4-(3-fluoropyridin-2-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C17H23FN6O2	1
1	EC50 = 0.8 nM Bioactivity Info	TI LI LO TS
CP0375987 Compound Info	N-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]-4-fluorobenzamide Show/Hide	C21H24FN3O3	2
1	EC50 = 0.8511 nM Bioactivity Info	TI LI LO TS
2	EC50 = 0.955 nM Bioactivity Info	TI LI LO TS
CP0492306 Compound Info	N-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H23FN2O3	3
1	EC50 = 1.1 nM Bioactivity Info	TI LI LO TS
2	EC50 = 15.7 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.7 nM Bioactivity Info	TI LI LO TS
CP0096732 Compound Info	1-[3-(5-Methoxy-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine Show/Hide	C23H27N3O	1
1	EC50 = 1.259 nM Bioactivity Info	TI LI LO TS
CP0860451 Compound Info	[3-(1H-Indol-2-yl)-propyl]-[2-(2-methoxy-phenoxy)-ethyl]-amine Show/Hide	C20H24N2O2	3
1	EC50 = 1.3 nM Bioactivity Info	TI LI LO TS
2	EC50 = 13 nM Bioactivity Info	TI LI LO TS
3	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0376359 Compound Info	2-[4-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]butyl]isoindole-1,3-dione Show/Hide	C24H27N3O4	2
1	EC50 = 1.349 nM Bioactivity Info	TI LI LO TS
2	EC50 = 5.754 nM Bioactivity Info	TI LI LO TS
CP0402227 Compound Info	N-[2-(1H-benzimidazol-4-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C20H21FN4O	3
1	EC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7.2 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.69 nM Bioactivity Info	TI LI LO TS
CP0378488 Compound Info	N-[2-(1H-benzimidazol-4-yloxy)ethyl]-3-(1H-indol-3-yl)propan-1-amine Show/Hide	C20H22N4O	3
1	EC50 = 1.6 nM Bioactivity Info	TI LI LO TS
2	EC50 = 8.7 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.87 nM Bioactivity Info	TI LI LO TS
CP0409153 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]propan-1-amine Show/Hide	C21H22FN3O	2
1	EC50 = 2 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0475482 Compound Info	7-Acetyl-3-amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyridin-4-one Show/Hide	C27H31N7O2S2	2
1	EC50 = 2.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.5 nM Bioactivity Info	TI LI LO TS
CP0037227 Compound Info	7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol Show/Hide	C16H25NO	11
1	EC50 = 2.6 nM Bioactivity Info	TI LI LO TS
2	EC50 = 10.9 nM Bioactivity Info	TI LI LO TS
3	EC50 = 12.02 nM Bioactivity Info	TI LI LO TS
4	EC50 = 15 nM Bioactivity Info	TI LI LO TS
5	EC50 = 26 nM Bioactivity Info	TI LI LO TS
6	EC50 = 51.29 nM Bioactivity Info	TI LI LO TS
7	Ki = 0.4 nM Bioactivity Info	TI LI LO TS
8	Ki = 0.71 nM Bioactivity Info	TI LI LO TS
9	Ki = 0.8 nM Bioactivity Info	TI LI LO TS
10	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
11	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0409104 Compound Info	4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-1-phenyl-butan-1-one; hydrochloride Show/Hide	C22H26N2O3	2
1	EC50 = 2.818 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2.884 nM Bioactivity Info	TI LI LO TS
CP0398894 Compound Info	N-[2-(1-benzofuran-7-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H21FN2O2	2
1	EC50 = 2.9 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0142893 Compound Info	1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)-propyl]-4-pyridin-2-yl-piperazine Show/Hide	C23H29N3O	2
1	EC50 = 2.951 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3388.44 nM Bioactivity Info	TI LI LO TS
CP0409450 Compound Info	3-(1H-indol-3-yl)-N-(2-quinolin-8-yloxyethyl)propan-1-amine Show/Hide	C22H23N3O	2
1	EC50 = 3 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.54 nM Bioactivity Info	TI LI LO TS
CP0381559 Compound Info	1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-ethyl]-4-pyridin-2-yl-piperazine Show/Hide	C22H29N3O	2
1	EC50 = 3.548 nM Bioactivity Info	TI LI LO TS
2	EC50 = 20.89 nM Bioactivity Info	TI LI LO TS
CP0001238 Compound Info	14C-5-hydroxy tryptamine creatinine disulfate Show/Hide	C10H12N2O	7
1	EC50 = 3.7 nM Bioactivity Info	TI LI LO TS
2	EC50 = 27.54 nM Bioactivity Info	TI LI LO TS
3	EC50 = 147 nM Bioactivity Info	TI LI LO TS
4	EC50 = 150 nM Bioactivity Info	TI LI LO TS
5	EC50 = 169.82 nM Bioactivity Info	TI LI LO TS
6	Ki = 3 nM Bioactivity Info	TI LI LO TS
7	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0425330 Compound Info	3-(1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]propan-1-amine Show/Hide	C21H23N3O	2
1	EC50 = 4 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0301974 Compound Info	(+/-)-6-fluoro-9-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C23H23F2N3O2	2
1	EC50 = 4 nM Bioactivity Info	TI LI LO TS
2	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0415398 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(2-methoxyphenoxy)ethyl]propan-1-amine Show/Hide	C20H23FN2O2	3
1	EC50 = 4.3 nM Bioactivity Info	TI LI LO TS
2	EC50 = 41.6 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0392495 Compound Info	N-[2-(2,3-dihydro-1-benzofuran-7-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H23FN2O2	2
1	EC50 = 4.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0376270 Compound Info	4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride Show/Hide	C22H25FN2O3	2
1	EC50 = 5.248 nM Bioactivity Info	TI LI LO TS
2	EC50 = 7.413 nM Bioactivity Info	TI LI LO TS
CP0384018 Compound Info	1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-butyl)-piperazine; hydrochloride Show/Hide	C22H28N2O2	2
1	EC50 = 6.026 nM Bioactivity Info	TI LI LO TS
2	EC50 = 6.761 nM Bioactivity Info	TI LI LO TS
CP0469270 Compound Info	(3-chloro-4-fluorophenyl)(4-hydroxy-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C20H23ClFN3O2	1
1	EC50 = 6.6 nM Bioactivity Info	TI LI LO TS
CP0384728 Compound Info	Flesinoxan Show/Hide	C22H26FN3O4	1
1	EC50 = 6.607 nM Bioactivity Info	TI LI LO TS
CP0037866 Compound Info	CAS_146714-97-8 Show/Hide	C25H34N4O2	5
1	EC50 = 7.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7.1 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.5012 nM Bioactivity Info	TI LI LO TS
4	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
5	Ki = 0.96 nM Bioactivity Info	TI LI LO TS
CP0519982 Compound Info	(3-chloro-4-fluorophenyl)(4-fluoro-4-((methyl((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone Show/Hide	C21H24ClF2N3O	1
1	EC50 = 8.6 nM Bioactivity Info	TI LI LO TS
CP0345077 Compound Info	(+/-)-9-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C25H28FN3O2	2
1	EC50 = 9 nM Bioactivity Info	TI LI LO TS
2	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0492237 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-(2-quinolin-5-yloxyethyl)propan-1-amine Show/Hide	C22H22FN3O	3
1	EC50 = 9.06 nM Bioactivity Info	TI LI LO TS
2	EC50 = 35 nM Bioactivity Info	TI LI LO TS
3	Ki = 35.5 nM Bioactivity Info	TI LI LO TS
CP0135904 Compound Info	(+/-)-9-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-6-fluoro-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C25H27F2N3O2	2
1	EC50 = 10 nM Bioactivity Info	TI LI LO TS
2	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0066631 Compound Info	1-benzothiophen-3-yl-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone Show/Hide	C22H24FN3OS	1
1	EC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0406267 Compound Info	Adamantan-1-yl-(4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-methanone Show/Hide	C24H34FN3O	1
1	EC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0388708 Compound Info	(4-Fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-thiophen-3-yl-methanone Show/Hide	C18H22FN3OS	1
1	EC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0372242 Compound Info	N-[4-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]butyl]-4-fluorobenzamide Show/Hide	C23H28FN3O3	2
1	EC50 = 12.59 nM Bioactivity Info	TI LI LO TS
2	EC50 = 31.62 nM Bioactivity Info	TI LI LO TS
CP0469394 Compound Info	[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]-phenylmethanone Show/Hide	C20H24FN3O	1
1	EC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0430956 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-(2-quinoxalin-5-yloxyethyl)propan-1-amine Show/Hide	C21H21FN4O	3
1	EC50 = 13.7 nM Bioactivity Info	TI LI LO TS
2	EC50 = 46 nM Bioactivity Info	TI LI LO TS
3	Ki = 9.8 nM Bioactivity Info	TI LI LO TS
CP0406048 Compound Info	3-Amino-2-[4-[4-(4-methylquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C26H34N6O	2
1	EC50 = 13.7 nM Bioactivity Info	TI LI LO TS
2	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0487926 Compound Info	(4-Fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-furan-2-yl-methanone Show/Hide	C18H22FN3O2	1
1	EC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0127598 Compound Info	1-benzofuran-3-yl-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone Show/Hide	C22H24FN3O2	1
1	EC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0066630 Compound Info	(4-bromothiophen-2-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C18H21BrFN3OS	1
1	EC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0385730 Compound Info	(3-chloro-4-fluorophenyl)(3-hydroxy-3-(((5-methylpyridin-2-yl)methylamino)methyl)-8-azabicyclo[3.2.1]octan-8-yl)methanone Show/Hide	C22H25ClFN3O2	1
1	EC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0472813 Compound Info	(4-Fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-thiophen-2-yl-methanone Show/Hide	C18H22FN3OS	1
1	EC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0181682 Compound Info	(+)-3-(4-((cyclopropylmethyl)(1-oxo-1,2,3,7,8,9-hexahydropyrano[3,2-e]isoindol-8-yl)amino)butyl)-1H-indole-5-carbonitrile Show/Hide	C28H30N4O2	1
1	EC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0374234 Compound Info	(3-bromothiophen-2-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C18H21BrFN3OS	1
1	EC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0473699 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(4-methylthiophen-2-yl)methanone Show/Hide	C19H24FN3OS	1
1	EC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0345081 Compound Info	(+/-)-3-(3-(1-oxo-1,2,3,7,8,9-hexahydropyrano[3,2-e]isoindol-8-ylamino)propyl)-1H-indole-5-carbonitrile Show/Hide	C23H22N4O2	2
1	EC50 = 22 nM Bioactivity Info	TI LI LO TS
2	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0053464 Compound Info	3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)butyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one Show/Hide	C25H32N6O	2
1	EC50 = 22.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0328613 Compound Info	(+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one Show/Hide	C26H28FN3O2	1
1	EC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0341796 Compound Info	(+/-)-9-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C23H24FN3O2	2
1	EC50 = 25 nM Bioactivity Info	TI LI LO TS
2	Ki = 44 nM Bioactivity Info	TI LI LO TS
CP0415516 Compound Info	4-(1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]butan-1-amine Show/Hide	C22H25N3O	2
1	EC50 = 25.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 4.2 nM Bioactivity Info	TI LI LO TS
CP0332108 Compound Info	(+/-)-9-((3-(5-fluoro-1H-indol-3-yl)propyl)(methyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C24H26FN3O2	2
1	EC50 = 26 nM Bioactivity Info	TI LI LO TS
2	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0472808 Compound Info	1-bicyclo[3.3.1]nonanyl-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone Show/Hide	C23H34FN3O	1
1	EC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0289234 Compound Info	(+/-)-8-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one Show/Hide	C24H26FN3O2	2
1	EC50 = 28 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0478835 Compound Info	(5-bromothiophen-2-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C18H21BrFN3OS	1
1	EC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0504413 Compound Info	(3-chlorothiophen-2-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C18H21ClFN3OS	1
1	EC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0354715 Compound Info	3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3H-quinazolin-4-one Show/Hide	C25H28N6O	2
1	EC50 = 30.7 nM Bioactivity Info	TI LI LO TS
2	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0374223 Compound Info	(3-hydroxy-3-(((5-methylpyridin-2-yl)methylamino)methyl)-8-azabicyclo[3.2.1]octan-8-yl)(thiophen-3-yl)methanone Show/Hide	C20H25N3O2S	1
1	EC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0419463 Compound Info	2-(1H-indol-3-yl)-N-((4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C20H23N3O	2
1	EC50 = 33.6 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.86 nM Bioactivity Info	TI LI LO TS
CP0240352 Compound Info	(+/-)-9-((3-(5-fluoro-1H-indol-3-yl)propyl)(propyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C26H30FN3O2	2
1	EC50 = 34 nM Bioactivity Info	TI LI LO TS
2	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0502953 Compound Info	1-benzofuran-2-yl-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone Show/Hide	C22H24FN3O2	1
1	EC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0377231 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(3-methylthiophen-2-yl)methanone Show/Hide	C19H24FN3OS	1
1	EC50 = 35 nM Bioactivity Info	TI LI LO TS
CP0281204 Compound Info	(+/-)-9-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C27H30FN3O2	2
1	EC50 = 36 nM Bioactivity Info	TI LI LO TS
2	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0388698 Compound Info	1-benzotellurophen-2-yl-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone Show/Hide	C22H24FN3OTe	1
1	EC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0473619 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(thieno[2,3-b]thiophen-2-yl)methanone Show/Hide	C20H22FN3OS2	1
1	EC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0152465 Compound Info	4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(2-methoxyethyl)pyrimidin-2-amine Show/Hide	C22H29N5O	1
1	EC50 = 40.7 nM Bioactivity Info	TI LI LO TS
CP0042717 Compound Info	(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione Show/Hide	C21H31N5O2	2
1	EC50 = 41 nM Bioactivity Info	TI LI LO TS
2	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0487922 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(5-methylthiophen-2-yl)methanone Show/Hide	C19H24FN3OS	1
1	EC50 = 42 nM Bioactivity Info	TI LI LO TS
CP0392699 Compound Info	4-(1H-indol-3-yl)-N-[2-(2-methoxyphenoxy)ethyl]butan-1-amine Show/Hide	C21H26N2O2	2
1	EC50 = 44 nM Bioactivity Info	TI LI LO TS
2	Ki = 7.7 nM Bioactivity Info	TI LI LO TS
CP0504414 Compound Info	(5-chlorothiophen-2-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C18H21ClFN3OS	1
1	EC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0406268 Compound Info	(4-Fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-(hexahydro-2,5-methano-pentalen-3a-yl)-methanone Show/Hide	C23H32FN3O	1
1	EC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0502954 Compound Info	(3-Chloro-adamantan-1-yl)-(4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-methanone Show/Hide	C24H33ClFN3O	1
1	EC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0135906 Compound Info	(+/-)-8-((cyclopropylmethyl)(4-(5-fluoro-1H-indol-3-yl)butyl)amino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one Show/Hide	C27H30FN3O2	2
1	EC50 = 49 nM Bioactivity Info	TI LI LO TS
2	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0377233 Compound Info	(5-chloro-4-methoxythiophen-3-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C19H23ClFN3O2S	1
1	EC50 = 50 nM Bioactivity Info	TI LI LO TS
CP0158311 Compound Info	3-(4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)pyrimidin-2-ylamino)propan-1-ol Show/Hide	C22H29N5O	1
1	EC50 = 51.4 nM Bioactivity Info	TI LI LO TS
CP0473703 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(naphthalen-2-yl)methanone Show/Hide	C24H26FN3O	1
1	EC50 = 52 nM Bioactivity Info	TI LI LO TS
CP0460131 Compound Info	2-(5-fluoro-1H-indol-3-yl)-N-((8-methoxy-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C20H22FN3O2	2
1	EC50 = 52.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 9.31 nM Bioactivity Info	TI LI LO TS
CP0289232 Compound Info	(+/-)-9-(cyclobutyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C27H30FN3O2	2
1	EC50 = 54 nM Bioactivity Info	TI LI LO TS
2	Ki = 95 nM Bioactivity Info	TI LI LO TS
CP0514578 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(5-(methylthio)thiophen-2-yl)methanone Show/Hide	C19H24FN3OS2	1
1	EC50 = 54 nM Bioactivity Info	TI LI LO TS
CP0375892 Compound Info	N-[2-[(5-fluoro-1-benzofuran-7-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H20F2N2O2	3
1	EC50 = 56 nM Bioactivity Info	TI LI LO TS
2	IC50 = 107 nM Bioactivity Info	TI LI LO TS
3	Ki = 12.9 nM Bioactivity Info	TI LI LO TS
CP0421899 Compound Info	11-Allyloxy-N-methylaporphine Show/Hide	C20H21NO	3
1	EC50 = 56 nM Bioactivity Info	TI LI LO TS
2	IC50 = 323 nM Bioactivity Info	TI LI LO TS
3	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0470408 Compound Info	(3-chlorothieno[2,3-b]thiophen-2-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C20H21ClFN3OS2	1
1	EC50 = 59 nM Bioactivity Info	TI LI LO TS
CP0404457 Compound Info	3-(1H-indol-3-yl)-N-(2-naphthalen-1-yloxyethyl)propan-1-amine Show/Hide	C23H24N2O	2
1	EC50 = 60.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 16.8 nM Bioactivity Info	TI LI LO TS
CP0289233 Compound Info	(+/-)-8-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one Show/Hide	C22H22FN3O2	2
1	EC50 = 62 nM Bioactivity Info	TI LI LO TS
2	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0527213 Compound Info	(5-bromo-4-methoxythiophen-3-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C19H23BrFN3O2S	1
1	EC50 = 62 nM Bioactivity Info	TI LI LO TS
CP0473505 Compound Info	(7-bromo-2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone Show/Hide	C20H23BrFN3O3S	1
1	EC50 = 63 nM Bioactivity Info	TI LI LO TS
CP0230830 Compound Info	4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(3-methoxypropyl)pyrimidin-2-amine Show/Hide	C23H31N5O	1
1	EC50 = 65 nM Bioactivity Info	TI LI LO TS
CP0059583 Compound Info	1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda6-benzo[d]isothiazol-3-one Show/Hide	C19H23N5O3S	2
1	EC50 = 67.61 nM Bioactivity Info	TI LI LO TS
2	Ki = 49.7 nM Bioactivity Info	TI LI LO TS
CP0345079 Compound Info	(+/-)-8-((3-(5-fluoro-1H-indol-3-yl)propyl)(methyl)amino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one Show/Hide	C23H24FN3O2	2
1	EC50 = 75 nM Bioactivity Info	TI LI LO TS
2	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0447707 Compound Info	(5R,12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene Show/Hide	C20H21NO	2
1	EC50 = 86 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.1 nM Bioactivity Info	TI LI LO TS
CP0412017 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(4,5,6,7-tetrahydrobenzo[c]thiophen-1-yl)methanone Show/Hide	C22H28FN3OS	1
1	EC50 = 86 nM Bioactivity Info	TI LI LO TS
CP0034681 Compound Info	N-[(4-ethyl-2,3-dihydro-1,4-benzoxazin-2-yl)methyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C21H24FN3O	2
1	EC50 = 90 nM Bioactivity Info	TI LI LO TS
2	Ki = 15.31 nM Bioactivity Info	TI LI LO TS
CP0473701 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(pyrazolo[1,5-a]pyridin-2-yl)methanone Show/Hide	C21H24FN5O	1
1	EC50 = 93 nM Bioactivity Info	TI LI LO TS
CP0469322 Compound Info	N-(3,4-dihydro-2H-1,4-benzoxazin-2-ylmethyl)-2-(1H-indol-3-yl)ethanamine Show/Hide	C19H21N3O	2
1	EC50 = 93.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 6.91 nM Bioactivity Info	TI LI LO TS
CP0866951 Compound Info	[3-(5-Fluoro-1H-indol-2-yl)-propyl]-(2-phenoxy-ethyl)-amine Show/Hide	C19H21FN2O	2
1	EC50 = 97.4 nM Bioactivity Info	TI LI LO TS
2	Ki = 9.2 nM Bioactivity Info	TI LI LO TS
CP0469393 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(4-methoxythiophen-3-yl)methanone Show/Hide	C19H24FN3O2S	1
1	EC50 = 99 nM Bioactivity Info	TI LI LO TS
CP0473702 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(1H-indol-5-yl)methanone Show/Hide	C22H25FN4O	1
1	EC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0308903 Compound Info	(+/-)-9-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-6-fluoro-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C27H29F2N3O2	2
1	EC50 = 101 nM Bioactivity Info	TI LI LO TS
2	Ki = 50 nM Bioactivity Info	TI LI LO TS
CP0377228 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(thieno[3,2-b]thiophen-2-yl)methanone Show/Hide	C20H22FN3OS2	1
1	EC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0255491 Compound Info	2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-8-methoxy-4-propyl-3,4-dihydro-2H-benzo[b][1,4]oxazine Show/Hide	C26H30FN3O2	2
1	EC50 = 135 nM Bioactivity Info	TI LI LO TS
2	Ki = 362.8 nM Bioactivity Info	TI LI LO TS
CP0322305 Compound Info	(+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-cyclopropylpyrimidin-2-amine Show/Hide	C22H27N5	1
1	EC50 = 138 nM Bioactivity Info	TI LI LO TS
CP0191791 Compound Info	(+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(1-cyclopropylethyl)pyrimidin-2-amine Show/Hide	C24H31N5	1
1	EC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0194739 Compound Info	(+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(cyclopropylmethyl)pyrimidin-2-amine Show/Hide	C23H29N5	1
1	EC50 = 147 nM Bioactivity Info	TI LI LO TS
CP0161769 Compound Info	N-(3,4-dihydro-2H-1,4-benzoxazin-2-ylmethyl)-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C19H20FN3O	2
1	EC50 = 155 nM Bioactivity Info	TI LI LO TS
2	Ki = 10.98 nM Bioactivity Info	TI LI LO TS
CP0308163 Compound Info	2-(5-fluoro-1H-indol-3-yl)-N-((4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C20H22FN3O	2
1	EC50 = 167.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 8.46 nM Bioactivity Info	TI LI LO TS
CP0371039 Compound Info	N-cyclopropyl-4-[1-[2-(5-fluoro-1H-indol-3-yl)ethyl]piperidin-3-yl]pyrimidin-2-amine Show/Hide	C22H26FN5	1
1	EC50 = 169 nM Bioactivity Info	TI LI LO TS
CP0502639 Compound Info	11-Propargyloxy-N-methylaporphine Show/Hide	C20H19NO	2
1	EC50 = 180 nM Bioactivity Info	TI LI LO TS
2	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0187001 Compound Info	2-(5-fluoro-1H-indol-3-yl)-N-((7-methoxy-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C20H22FN3O2	2
1	EC50 = 181.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 103 nM Bioactivity Info	TI LI LO TS
CP0475500 Compound Info	3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C24H30N6OS	2
1	EC50 = 182 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5.6 nM Bioactivity Info	TI LI LO TS
CP0250913 Compound Info	2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-8-methoxy-4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine Show/Hide	C24H26FN3O2	2
1	EC50 = 190 nM Bioactivity Info	TI LI LO TS
2	Ki = 139.9 nM Bioactivity Info	TI LI LO TS
CP0377739 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-(dithiolan-3-yl)pentanoate Show/Hide	C27H33NO2S2	2
1	EC50 = 190 nM Bioactivity Info	TI LI LO TS
2	Ki = 66 nM Bioactivity Info	TI LI LO TS
CP0255492 Compound Info	2-(5-fluoro-1H-indol-3-yl)-N-((4-isopropyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C22H26FN3O	2
1	EC50 = 190.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.81 nM Bioactivity Info	TI LI LO TS
CP0250917 Compound Info	2-(1H-indol-3-yl)-N-((4-propyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C22H27N3O	2
1	EC50 = 196.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 12.76 nM Bioactivity Info	TI LI LO TS
CP0376635 Compound Info	(rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)butyl)-1-m-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C37H48N6O3	2
1	EC50 = 200 nM Bioactivity Info	TI LI LO TS
2	Ki = 133 nM Bioactivity Info	TI LI LO TS
CP0658701 Compound Info	1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride Show/Hide	C18H23ClN2S	1
1	EC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0127497 Compound Info	N-cyclopropyl-4-[1-[2-(7-fluoro-1H-indol-3-yl)ethyl]piperidin-3-yl]pyrimidin-2-amine Show/Hide	C22H26FN5	1
1	EC50 = 216 nM Bioactivity Info	TI LI LO TS
CP0388709 Compound Info	(4-Fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-furan-3-yl-methanone Show/Hide	C18H22FN3O2	1
1	EC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0406272 Compound Info	1-benzothiophen-2-yl-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone Show/Hide	C22H24FN3OS	1
1	EC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0376353 Compound Info	2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]-1,1-dioxo-1,2-benzothiazol-3-one Show/Hide	C21H23N3O5S	2
1	EC50 = 251.19 nM Bioactivity Info	TI LI LO TS
2	EC50 = 630.96 nM Bioactivity Info	TI LI LO TS
CP0308904 Compound Info	(+/-)-9-((3-(5-fluoro-1H-indol-3-yl)propyl)(isopropyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C26H30FN3O2	2
1	EC50 = 252 nM Bioactivity Info	TI LI LO TS
2	Ki = 129 nM Bioactivity Info	TI LI LO TS
CP0850840 Compound Info	exo-8-Benzoyl-3-[[[(5-methylpyridin-2-yl)methyl]amino]methyl]-8-azabicyclo[3.2.1]octan-3-ol (exo-CH2) Show/Hide	C22H27N3O2	1
1	EC50 = 270 nM Bioactivity Info	TI LI LO TS
CP0135905 Compound Info	(+/-)-8-(4-(5-fluoro-1H-indol-3-yl)butylamino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one Show/Hide	C23H24FN3O2	2
1	EC50 = 284 nM Bioactivity Info	TI LI LO TS
2	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0191793 Compound Info	N-cyclopropyl-4-[1-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]piperidin-3-yl]pyrimidin-2-amine Show/Hide	C23H30N4	1
1	EC50 = 290 nM Bioactivity Info	TI LI LO TS
CP0473617 Compound Info	(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)(pyrazolo[1,5-a]pyridin-3-yl)methanone Show/Hide	C21H24FN5O	1
1	EC50 = 310 nM Bioactivity Info	TI LI LO TS
CP0187000 Compound Info	2-(5-fluoro-1H-indol-3-yl)-N-((4-isobutyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C23H28FN3O	2
1	EC50 = 329 nM Bioactivity Info	TI LI LO TS
2	Ki = 8.15 nM Bioactivity Info	TI LI LO TS
CP0250916 Compound Info	3-(1H-indol-3-yl)-N-((4-isopropyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)propan-1-amine Show/Hide	C23H29N3O	2
1	EC50 = 329 nM Bioactivity Info	TI LI LO TS
2	Ki = 90.42 nM Bioactivity Info	TI LI LO TS
CP0376636 Compound Info	(rac)-3-(3-(4-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-1-yl)propyl)-1-o-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C36H46N6O3	2
1	EC50 = 330 nM Bioactivity Info	TI LI LO TS
2	Ki = 105 nM Bioactivity Info	TI LI LO TS
CP0171301 Compound Info	N-[(7-chloro-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl)methyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C20H21ClFN3O	2
1	EC50 = 336 nM Bioactivity Info	TI LI LO TS
2	Ki = 75.18 nM Bioactivity Info	TI LI LO TS
CP0345080 Compound Info	(+/-)-8-(cyclobutyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one Show/Hide	C26H28FN3O2	2
1	EC50 = 350 nM Bioactivity Info	TI LI LO TS
2	Ki = 101 nM Bioactivity Info	TI LI LO TS
CP0057346 Compound Info	3-(2-aminopropyl)-1H-indol-5-ol Show/Hide	C11H14N2O	1
1	EC50 = 378 nM Bioactivity Info	TI LI LO TS
CP0311888 Compound Info	2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-8-methoxy-3,4-dihydro-2H-benzo[b][1,4]oxazine Show/Hide	C23H24FN3O2	2
1	EC50 = 386 nM Bioactivity Info	TI LI LO TS
2	Ki = 154.85 nM Bioactivity Info	TI LI LO TS
CP0280304 Compound Info	4-ethyl-2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-8-methoxy-3,4-dihydro-2H-benzo[b][1,4]oxazine Show/Hide	C25H28FN3O2	2
1	EC50 = 418 nM Bioactivity Info	TI LI LO TS
2	Ki = 136.45 nM Bioactivity Info	TI LI LO TS
CP0281206 Compound Info	(+/-)-N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-(1-oxo-1,2,3,7,8,9-hexahydropyrano[3,2-e]isoindol-8-yl)benzamide Show/Hide	C29H26FN3O3	2
1	EC50 = 436 nM Bioactivity Info	TI LI LO TS
2	Ki = 85 nM Bioactivity Info	TI LI LO TS
CP0099665 Compound Info	2-(5-Methoxy-1H-indol-3-yl)-1-methyl-ethylamine Show/Hide	C12H16N2O	1
1	EC50 = 564 nM Bioactivity Info	TI LI LO TS
CP0406270 Compound Info	(4-Fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-(3-hydroxy-adamantan-1-yl)-methanone Show/Hide	C24H34FN3O2	1
1	EC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0418454 Compound Info	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-7-sulfonamide Show/Hide	C23H26Cl2N4O2S	1
1	EC50 = 865 nM Bioactivity Info	TI LI LO TS
CP0343973 Compound Info	2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine Show/Hide	C22H23N3O	2
1	EC50 = 1131 nM Bioactivity Info	TI LI LO TS
2	Ki = 804.8 nM Bioactivity Info	TI LI LO TS
CP0250915 Compound Info	N-[(4-benzyl-2,3-dihydro-1,4-benzoxazin-2-yl)methyl]-3-(1H-indol-3-yl)propan-1-amine Show/Hide	C27H29N3O	2
1	EC50 = 1385 nM Bioactivity Info	TI LI LO TS
2	Ki = 76.14 nM Bioactivity Info	TI LI LO TS
CP0044585 Compound Info	1-((S)-2-aminopropyl)-1H-indazol-6-ol Show/Hide	C10H13N3O	2
1	EC50 = 1460 nM Bioactivity Info	TI LI LO TS
2	Ki = 141 nM Bioactivity Info	TI LI LO TS
CP0068173 Compound Info	2-Aminopyrimidine analog., 4 Show/Hide	C16H18N6	1
1	EC50 = 1621.81 nM Bioactivity Info	TI LI LO TS
CP0418452 Compound Info	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-3-sulfonamide Show/Hide	C23H26Cl2N4O2S	1
1	EC50 = 1650 nM Bioactivity Info	TI LI LO TS
CP0372472 Compound Info	1-((R)-2-aminopropyl)-1H-indazol-6-ol Show/Hide	C10H13N3O	1
1	EC50 = 2890 nM Bioactivity Info	TI LI LO TS
CP0418456 Compound Info	N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]quinoline-7-sulfonamide Show/Hide	C22H24Cl2N4O2S	1
1	EC50 = 7400 nM Bioactivity Info	TI LI LO TS
CP0057042 Compound Info	(R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Show/Hide	C11H16INO2	1
1	EC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0103855 Compound Info	1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine Show/Hide	C14H18N2O	1
1	EC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0163540 Compound Info	1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine Show/Hide	C15H20N2O	1
1	EC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0418453 Compound Info	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-4-sulfonamide Show/Hide	C23H26Cl2N4O2S	1
1	EC50 = 15000 nM Bioactivity Info	TI LI LO TS
CP0418455 Compound Info	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-3-sulfonamide Show/Hide	C23H26Cl2N4O2S	1
1	EC50 = 15500 nM Bioactivity Info	TI LI LO TS
CP0454496 Compound Info	3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3Hpyrido[3,2-d]pyrimidin-4-one Show/Hide	C23H25N7OS	1
1	IC50 < 1 nM Bioactivity Info	TI LI LO TS
CP0493374 Compound Info	3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7-trihydro-3H-cyclopenta[d]pyrimidin-4-one Show/Hide	C24H30N6O	1
1	IC50 < 1 nM Bioactivity Info	TI LI LO TS
CP0524112 Compound Info	3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3Hpyrido[2,3-d]pyrimidin-4-one Show/Hide	C23H25N7OS	1
1	IC50 < 1 nM Bioactivity Info	TI LI LO TS
CP0379594 Compound Info	3-Amino-7-nitro-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-quinazolin-4-one Show/Hide	C24H25N7O3S	1
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0430030 Compound Info	8-{4-[4-(6-Methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-4-methylquinoline Show/Hide	C29H33N5O	2
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.61 nM Bioactivity Info	TI LI LO TS
CP0473123 Compound Info	5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}Quinoline Show/Hide	C28H30FN5O	2
1	IC50 = 2.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.4 nM Bioactivity Info	TI LI LO TS
CP0373381 Compound Info	5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-2,4-dimethylquinoline Show/Hide	C30H34FN5O	2
1	IC50 = 2.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 177 nM Bioactivity Info	TI LI LO TS
CP0513983 Compound Info	6-Methoxy-8-{4-[1-(8-quinolinyl)-4-piperidinyl]-1-piperazinyl}-quinoline Show/Hide	C28H31N5O	2
1	IC50 = 3.9 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.4 nM Bioactivity Info	TI LI LO TS
CP0699181 Compound Info	N-{2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl}-N-(2-pyridinyl)cyclohexane carboxamide trihydrochloride Show/Hide	C25H37Cl3N4O2	6
1	IC50 = 4.04 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7.06 nM Bioactivity Info	TI LI LO TS
3	IC50 = 7.1 nM Bioactivity Info	TI LI LO TS
4	IC50 = 8.4 nM Bioactivity Info	TI LI LO TS
5	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
6	Ki = 0.96 nM Bioactivity Info	TI LI LO TS
CP0435322 Compound Info	4-Chloro-N-{(R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide Show/Hide	C27H29ClN4O3	3
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 33 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0386016 Compound Info	3-Amino-5,6-dimethyl-2-[3-(4-pyridin-2-ylpiperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C20H26N6OS2	1
1	IC50 = 4.2 nM Bioactivity Info	TI LI LO TS
CP0377954 Compound Info	N-[(2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl]-4-nitro-N-pyridin-2-ylbenzamide Show/Hide	C27H29N5O5	3
1	IC50 = 4.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 23.2 nM Bioactivity Info	TI LI LO TS
3	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0526306 Compound Info	3-Amino-5,6-dimethyl-2-[3-[4-(4-methylquinolin-2-yl)piperazin-1-yl]propylthio]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C25H30N6OS2	1
1	IC50 = 4.3 nM Bioactivity Info	TI LI LO TS
CP0373378 Compound Info	8-{4-[4-(6-Methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-2,4-dimethylquinoline Show/Hide	C30H35N5O	2
1	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.63 nM Bioactivity Info	TI LI LO TS
CP0526309 Compound Info	3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7, 8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyridin-4-one Show/Hide	C25H29N7OS2	1
1	IC50 = 5.2 nM Bioactivity Info	TI LI LO TS
CP0373109 Compound Info	3-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}Quinoline Show/Hide	C28H30FN5O	2
1	IC50 = 5.6 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.79 nM Bioactivity Info	TI LI LO TS
CP0473118 Compound Info	8-{4-[4-(6-Methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-3-methylquinoline Show/Hide	C29H33N5O	2
1	IC50 = 5.9 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.46 nM Bioactivity Info	TI LI LO TS
CP0524111 Compound Info	3-Amino-5,6-dimethyl-2-[3-[4-(5,6,7,8-tetrahydroquinolin-2-yl)-piperazin-1-yl]propylthio]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C24H32N6OS2	1
1	IC50 = 6.1 nM Bioactivity Info	TI LI LO TS
CP0377944 Compound Info	N-[(2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl]-N-pyridin-2-yl-4-(trifluoromethyl)benzamide Show/Hide	C28H29F3N4O3	3
1	IC50 = 6.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 32.1 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
CP0428010 Compound Info	2-[4-(4-Quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydro-3Hquinazolin-4-one Show/Hide	C25H31N5O	1
1	IC50 = 6.2 nM Bioactivity Info	TI LI LO TS
CP0400777 Compound Info	5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-2-(trifluoromethyl)-quinoline Show/Hide	C29H29F4N5O	2
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0502280 Compound Info	5-Amino-2-[5-(4-quinolin-2-ylpiperazin-1-yl)pentyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C26H34N6O	1
1	IC50 = 7.6 nM Bioactivity Info	TI LI LO TS
CP0430029 Compound Info	5-Fluoro-4-methoxy-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-2-(trifluoromethyl)quinoline Show/Hide	C30H31F4N5O2	2
1	IC50 = 9.1 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0376607 Compound Info	6-Bromo-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}Quinoline Show/Hide	C28H30BrN5O	2
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.61 nM Bioactivity Info	TI LI LO TS
CP0454497 Compound Info	3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7, 8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one Show/Hide	C26H30N6OS2	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0454499 Compound Info	3-Amino-6-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C25H27ClN6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0468972 Compound Info	3-Amino-5-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C25H27ClN6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0472688 Compound Info	3-Amino-6-hydroxy-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C25H32N6O2	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0472689 Compound Info	7-Acetyl-3-amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5, 6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one Show/Hide	C28H33N7O2S	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0475483 Compound Info	3-Amino-8-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C26H30N6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0479074 Compound Info	3-Amino-5,6-dimethyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C25H30N6OS	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0493375 Compound Info	3-Amino-6-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5, 6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C26H34N6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0493377 Compound Info	3-Amino-7-fluoro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C25H27FN6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0497744 Compound Info	3-Amino-5-fluoro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C25H27FN6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0497766 Compound Info	3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8,9-pentahydro-3H-cyclohepta[d]pyrimidin-4-one Show/Hide	C26H34N6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0497769 Compound Info	3-Amino-8-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C25H27ClN6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0523786 Compound Info	3-Amino-6-fluoro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C25H27FN6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0527689 Compound Info	3-Amino-7-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C26H34N6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0528014 Compound Info	3-Amino-6-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C26H30N6O	1
1	IC50 < 10 nM Bioactivity Info	TI LI LO TS
CP0454512 Compound Info	3-Amino-5-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C26H30N6O	1
1	IC50 = 13.5 nM Bioactivity Info	TI LI LO TS
CP0527160 Compound Info	5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-3-(trifluoromethyl)-quinoline Show/Hide	C29H29F4N5O	2
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.87 nM Bioactivity Info	TI LI LO TS
CP0439157 Compound Info	(5S,12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene Show/Hide	C20H21NO	2
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
2	Ki = 45.3 nM Bioactivity Info	TI LI LO TS
CP0502278 Compound Info	3-Amino-7-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one Show/Hide	C25H27ClN6O	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0376600 Compound Info	3,5-Difluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}quinoline Show/Hide	C28H29F2N5O	2
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.47 nM Bioactivity Info	TI LI LO TS
CP0399324 Compound Info	(3R)-(-)-N-Cyclobutyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxychroman-3-amine Show/Hide	C25H29FN2O2	3
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
2	IC50 = 488 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.14 nM Bioactivity Info	TI LI LO TS
CP0373380 Compound Info	8-{4-[4-(6-Methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-2-(trifluoromethyl)Quinoline Show/Hide	C29H30F3N5O	2
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.8 nM Bioactivity Info	TI LI LO TS
CP0381735 Compound Info	3-[cyclobutyl-[4-(5-fluoro-1H-indol-3-yl)butyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
2	Ki = 4.8 nM Bioactivity Info	TI LI LO TS
CP0497747 Compound Info	3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-quinazolin-4-one Show/Hide	C24H26N6OS	1
1	IC50 = 24.4 nM Bioactivity Info	TI LI LO TS
CP0374621 Compound Info	4-Cyano-N-{(R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide Show/Hide	C28H29N5O3	3
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
2	IC50 = 42 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0375390 Compound Info	(3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	3
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
2	IC50 = 48 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0376601 Compound Info	4-Methoxy-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-2-(trifluoromethyl)-quinoline Show/Hide	C30H32F3N5O2	2
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0376602 Compound Info	8-{4-[4-(6-Methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-3-(trifluoromethyl)Quinoline Show/Hide	C29H30F3N5O	2
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0404465 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-2-(1H-indol-3-yl)ethanamine Show/Hide	C21H23FN2O2	2
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
2	Ki = 8.5 nM Bioactivity Info	TI LI LO TS
CP0406049 Compound Info	3-Amino-5,6-dimethyl-2-[3-(4-quinolin-2-ylpiperazin-1-yl)-propylthio]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C24H28N6OS2	1
1	IC50 = 36.4 nM Bioactivity Info	TI LI LO TS
CP0482971 Compound Info	6-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}Quinoline Show/Hide	C28H30FN5O	2
1	IC50 = 46.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.4 nM Bioactivity Info	TI LI LO TS
CP0479068 Compound Info	3-Amino-2-[4-[4-(7-hydroxyquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C25H32N6O2	1
1	IC50 = 46.6 nM Bioactivity Info	TI LI LO TS
CP0514832 Compound Info	8-{4-[4-(6-Methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}-2-methylquinoline Show/Hide	C29H33N5O	2
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.54 nM Bioactivity Info	TI LI LO TS
CP0183973 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C22H24F2N2O2	3
1	IC50 = 49 nM Bioactivity Info	TI LI LO TS
2	IC50 = 121 nM Bioactivity Info	TI LI LO TS
3	Ki = 26.6 nM Bioactivity Info	TI LI LO TS
CP0449450 Compound Info	3-[cyclopropylmethyl-[4-(5-fluoro-1H-indol-3-yl)butyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0526307 Compound Info	3-Amino-5,6-dimethyl-2-[3-(4-phenanthridin-6-ylpiperazin-1-yl)-propylthio]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C28H30N6OS2	1
1	IC50 = 55.4 nM Bioactivity Info	TI LI LO TS
CP0398982 Compound Info	(S)-2-((4-(1H-Indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)-methyl)-8-methyl-2,3-dihydro-[1,4]dioxino-[2,3-f]quinoline Show/Hide	C26H25N3O2	2
1	IC50 = 56.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.02 nM Bioactivity Info	TI LI LO TS
CP0398350 Compound Info	2-(4-{[(2S)-8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl}-1,4-diazepan-1-yl)-quinoline-6-carbonitrile Show/Hide	C28H27N5O2	2
1	IC50 = 58 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0493380 Compound Info	3-Amino-2-[4-[4-(6-hydroxyquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C25H32N6O2	1
1	IC50 = 59.3 nM Bioactivity Info	TI LI LO TS
CP0401389 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	3
1	IC50 = 61 nM Bioactivity Info	TI LI LO TS
2	IC50 = 202 nM Bioactivity Info	TI LI LO TS
3	Ki = 9.3 nM Bioactivity Info	TI LI LO TS
CP0475498 Compound Info	3-Amino-2-[4-[4-(2,3-dihydro-1H-cyclopenta[c]quinolin-4-yl)-piperazin-1-yl]butyl]-5,6,7,8-tequinazolintrahydro-3H--4-one Show/Hide	C28H36N6O	1
1	IC50 = 62.3 nM Bioactivity Info	TI LI LO TS
CP0521978 Compound Info	3-Amino-2-[4-[4-(3,4-dimethylquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C27H36N6O	1
1	IC50 = 64.6 nM Bioactivity Info	TI LI LO TS
CP0395135 Compound Info	(R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol Show/Hide	C26H31FN6O	1
1	IC50 = 66 nM Bioactivity Info	TI LI LO TS
CP0376181 Compound Info	3-[cyclopropylmethyl-[3-(5-fluoro-1H-indol-3-yl)propyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C25H27F2N3O2	2
1	IC50 = 66 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
CP0846029 Compound Info	(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}chromane- Show/Hide	C25H29ClFN3O2	2
1	IC50 = 66 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.66 nM Bioactivity Info	TI LI LO TS
CP0402229 Compound Info	N-[2-[(6-chloro-1H-benzimidazol-4-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C20H20ClFN4O	3
1	IC50 = 66.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 238 nM Bioactivity Info	TI LI LO TS
3	Ki = 10.7 nM Bioactivity Info	TI LI LO TS
CP0521979 Compound Info	3-Amino-2-[3-(4-benzothiazol-2-ylpiperazin-1-yl)propylthio]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C22H26N6OS3	1
1	IC50 = 66.6 nM Bioactivity Info	TI LI LO TS
CP0381752 Compound Info	3-[ethyl-[2-(5-fluoro-1H-indol-3-yl)ethyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C22H23F2N3O2	2
1	IC50 = 68 nM Bioactivity Info	TI LI LO TS
2	Ki = 33.2 nM Bioactivity Info	TI LI LO TS
CP0394637 Compound Info	8-fluoro-3-[2-(5-fluoro-1H-indol-3-yl)ethyl-propylamino]-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C23H25F2N3O2	2
1	IC50 = 68 nM Bioactivity Info	TI LI LO TS
2	Ki = 17.6 nM Bioactivity Info	TI LI LO TS
CP0496910 Compound Info	(3R)-3-{(cyclopropylmethyl)[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	2
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0404890 Compound Info	(2S)-2-{[4-(6-Fluoroquinolin-2-yl)-1,4-diazepan-1-yl]methyl}-8-methyl-2,3-dihydro[1,4]dioxino-[2,3-f]quinoline Show/Hide	C27H27FN4O2	2
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0456053 Compound Info	(2S)-8-Methyl-2-[(4-quinolin-2-yl-1,4-diazepan-1-yl)methyl]-2,3-dihydro[1,4]dioxino[2,3-f]-quinoline Show/Hide	C27H28N4O2	2
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
2	Ki = 6.8 nM Bioactivity Info	TI LI LO TS
CP0354473 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C21H22F2N2O2	3
1	IC50 = 79 nM Bioactivity Info	TI LI LO TS
2	IC50 = 235 nM Bioactivity Info	TI LI LO TS
3	Ki = 29.2 nM Bioactivity Info	TI LI LO TS
CP0493344 Compound Info	3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C24H30N6O	1
1	IC50 = 90.4 nM Bioactivity Info	TI LI LO TS
CP0434736 Compound Info	N-cyclobutyl-3-[cyclobutyl-[3-(5-fluoro-1H-indol-3-yl)propyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C29H33F2N3O2	2
1	IC50 = 91.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 213.5 nM Bioactivity Info	TI LI LO TS
CP0454513 Compound Info	3-Amino-2-[4-[4-(3-methylquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C26H34N6O	1
1	IC50 = 96 nM Bioactivity Info	TI LI LO TS
CP0493343 Compound Info	3-Amino-2-[4-[4-(3-hydroxyquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C25H32N6O2	1
1	IC50 = 96.4 nM Bioactivity Info	TI LI LO TS
CP0449451 Compound Info	3-[cyclopropylmethyl-[2-(5-fluoro-1H-indol-3-yl)ethyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C24H25F2N3O2	2
1	IC50 = 97 nM Bioactivity Info	TI LI LO TS
2	Ki = 7.3 nM Bioactivity Info	TI LI LO TS
CP0398979 Compound Info	2-(4-{[(2S)-8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl}piperazin-1-yl)-quinoline-6-carbonitrile Show/Hide	C27H25N5O2	2
1	IC50 = 102.1 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0450951 Compound Info	(2S)-8-Methyl-2-{[(2R)-2-methyl-4-quinolin-2-ylpiperazin-1-yl]methyl}-2,3-dihydro[1,4]dioxino-[2,3-f]quinoline Show/Hide	C27H28N4O2	2
1	IC50 = 117 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0449452 Compound Info	8-fluoro-3-[4-(5-fluoro-1H-indol-3-yl)butyl-propylamino]-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C25H29F2N3O2	2
1	IC50 = 125 nM Bioactivity Info	TI LI LO TS
2	Ki = 4.4 nM Bioactivity Info	TI LI LO TS
CP0496802 Compound Info	(R)-3-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C23H25F2N3O2	2
1	IC50 = 135 nM Bioactivity Info	TI LI LO TS
2	Ki = 34.9 nM Bioactivity Info	TI LI LO TS
CP0376632 Compound Info	N-[2-[(5-fluoro-2,3-dihydro-1-benzofuran-7-yl)oxy]ethyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C20H20F2N2O2	2
1	IC50 = 138 nM Bioactivity Info	TI LI LO TS
2	Ki = 35.1 nM Bioactivity Info	TI LI LO TS
CP0469215 Compound Info	N-[2-[(7-fluoro-2,3-dihydro-1,4-benzodioxin-5-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H22F2N2O3	3
1	IC50 = 156 nM Bioactivity Info	TI LI LO TS
2	IC50 = 198 nM Bioactivity Info	TI LI LO TS
3	Ki = 22.4 nM Bioactivity Info	TI LI LO TS
CP0497332 Compound Info	(2S)-2-{[4-(6-Bromoquinolin-2-yl)piperazin-1-yl]methyl}-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinoline Show/Hide	C26H25BrN4O2	2
1	IC50 = 156 nM Bioactivity Info	TI LI LO TS
2	Ki = 17.2 nM Bioactivity Info	TI LI LO TS
CP0407580 Compound Info	2-(4-{[(2S)-8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl}piperazin-1-yl)quino-line-6-carboxamide Show/Hide	C27H27N5O3	2
1	IC50 = 164 nM Bioactivity Info	TI LI LO TS
2	Ki = 7.2 nM Bioactivity Info	TI LI LO TS
CP0404891 Compound Info	2-((3R)-3-Methyl-4-{[(2S)-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl}pipera-zin-1-yl)quinoline-6-carbonitrile Show/Hide	C28H27N5O2	2
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0401085 Compound Info	(+)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}chromane-5-carboxamide Show/Hide	C25H28FN3O2	1
1	IC50 = 184.5 nM Bioactivity Info	TI LI LO TS
CP0461384 Compound Info	3-{(Cyclopropylmethyl)[4-(7-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 = 204 nM Bioactivity Info	TI LI LO TS
2	Ki = 19.25 nM Bioactivity Info	TI LI LO TS
CP0399965 Compound Info	N-[2-(5-fluoro-2-methoxyphenoxy)ethyl]-2-(1H-indol-3-yl)ethanamine Show/Hide	C19H21FN2O2	2
1	IC50 = 208 nM Bioactivity Info	TI LI LO TS
2	Ki = 48 nM Bioactivity Info	TI LI LO TS
CP0375391 Compound Info	(3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-methylchromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 = 262 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.32 nM Bioactivity Info	TI LI LO TS
CP0398981 Compound Info	(2S)-8-Methyl-2-{[4-(6-nitroquinolin-2-yl)piperazin-1-yl]-methyl}-2,3-dihydro[1,4]dioxino[2,3-f]quinoline Show/Hide	C26H25N5O4	2
1	IC50 = 294 nM Bioactivity Info	TI LI LO TS
2	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0918962 Compound Info	N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporphine Show/Hide	C20H21NO	2
1	IC50 = 323 nM Bioactivity Info	TI LI LO TS
2	Ki = 6.7 nM Bioactivity Info	TI LI LO TS
CP0473120 Compound Info	7-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}Quinoline Show/Hide	C28H30FN5O	2
1	IC50 = 331 nM Bioactivity Info	TI LI LO TS
2	Ki = 276 nM Bioactivity Info	TI LI LO TS
CP0424393 Compound Info	(+)-3-{(Cyclopropylmethyl)[3-(5-fluoro-1H-indol-3-yl)-1-methylpropyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 = 333 nM Bioactivity Info	TI LI LO TS
CP0401383 Compound Info	3-{(Cyclopropylmethyl)[4-(6-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 = 371 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.25 nM Bioactivity Info	TI LI LO TS
CP0461385 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-cyclopropyl-8-fluorochromane-5-carboxamide Show/Hide	C28H31F2N3O2	2
1	IC50 = 395 nM Bioactivity Info	TI LI LO TS
2	Ki = 19.2 nM Bioactivity Info	TI LI LO TS
CP0375377 Compound Info	(3R)-(-)-8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}chromane-5-carboxamide Show/Hide	C24H27F2N3O2	2
1	IC50 = 405 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0401387 Compound Info	3-{Cyclobutyl[3-(5-methoxy-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H30FN3O3	2
1	IC50 = 419 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.19 nM Bioactivity Info	TI LI LO TS
CP0461388 Compound Info	3-{Cyclobutyl[4-(6-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 = 428 nM Bioactivity Info	TI LI LO TS
2	Ki = 12.83 nM Bioactivity Info	TI LI LO TS
CP0444092 Compound Info	N-[2-[(5-fluoro-2,3-dihydro-1-benzofuran-7-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H22F2N2O2	2
1	IC50 = 445 nM Bioactivity Info	TI LI LO TS
2	Ki = 17.1 nM Bioactivity Info	TI LI LO TS
CP0401090 Compound Info	3-{Cyclobutyl[3-(6-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	2
1	IC50 = 512 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.02 nM Bioactivity Info	TI LI LO TS
CP0401086 Compound Info	3-{Cyclobutyl[3-(7-methoxy-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H30FN3O3	2
1	IC50 = 557 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.22 nM Bioactivity Info	TI LI LO TS
CP0404892 Compound Info	(2S)-8-Methyl-2-({4-[6-(trifluoromethoxy)quinolin-2-yl]piperazin-1-yl}methyl)-2,3-dihydro-[1,4]dioxino[2,3-f]quinoline Show/Hide	C27H25F3N4O3	2
1	IC50 = 588 nM Bioactivity Info	TI LI LO TS
2	Ki = 172 nM Bioactivity Info	TI LI LO TS
CP0491299 Compound Info	8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-N-methylchromane-5-carboxamide Show/Hide	C25H29F2N3O2	2
1	IC50 = 617 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.81 nM Bioactivity Info	TI LI LO TS
CP0375378 Compound Info	3-[[3-(5-Chloro-1H-indol-3-yl)propyl](cyclobutyl)amino]-8-fluorochromane-5-carboxamide Show/Hide	C25H27ClFN3O2	2
1	IC50 = 735 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.98 nM Bioactivity Info	TI LI LO TS
CP0461386 Compound Info	(3R)-(-)-8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)-amino}-N-methylchromane-5-carboxamide Show/Hide	C25H29F2N3O2	2
1	IC50 = 752 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.64 nM Bioactivity Info	TI LI LO TS
CP0407581 Compound Info	(2S)-2-{[4-(6-Chloroquinolin-2-yl)piperazin-1-yl]methyl}-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinoline Show/Hide	C26H25ClN4O2	2
1	IC50 = 781 nM Bioactivity Info	TI LI LO TS
2	Ki = 214.1 nM Bioactivity Info	TI LI LO TS
CP0375388 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-propylchromane-5-carboxamide Show/Hide	C28H33F2N3O2	2
1	IC50 = 800 nM Bioactivity Info	TI LI LO TS
2	Ki = 196 nM Bioactivity Info	TI LI LO TS
CP0424392 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-methylchromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 = 812 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.35 nM Bioactivity Info	TI LI LO TS
CP0381753 Compound Info	(3S)-(+)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	3
1	IC50 = 926 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
3	Ki = 253 nM Bioactivity Info	TI LI LO TS
CP0510094 Compound Info	(2S)-8-Methyl-2-{[(2S)-2-methyl-4-quinolin-2-ylpiperazin-1-yl]methyl}-2,3-dihydro[1,4]dioxino-[2,3-f]quinoline Show/Hide	C27H28N4O2	2
1	IC50 = 1899 nM Bioactivity Info	TI LI LO TS
2	Ki = 167 nM Bioactivity Info	TI LI LO TS
CP0398980 Compound Info	(2S)-2-{[4-(6-Fluoroquinolin-2-yl)piperazin-1-yl]methyl}-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinoline Show/Hide	C26H25FN4O2	2
1	IC50 = 2165 nM Bioactivity Info	TI LI LO TS
2	Ki = 32.9 nM Bioactivity Info	TI LI LO TS
CP0497336 Compound Info	(2S)-8-Methyl-2-[(4-quinolin-2-ylpiperazin-1-yl)methyl]-2,3-dihydro[1,4]dioxino[2,3-f]quinoline Show/Hide	C26H26N4O2	2
1	IC50 = 4870 nM Bioactivity Info	TI LI LO TS
2	Ki = 47.3 nM Bioactivity Info	TI LI LO TS
CP0468974 Compound Info	3-Amino-2-[2-(4-quinolin-2-ylpiperazin-1-yl)ethyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C23H28N6O	1
1	IC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0475499 Compound Info	3-Amino-2-[2-(4-quinolin-2-ylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C22H26N6O	1
1	IC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0497743 Compound Info	2-[3-(4-Quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one Show/Hide	C26H29N5OS2	1
1	IC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0523785 Compound Info	5,6-Dimethyl-2-[3-(4-quinolin-2-yl-piperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C24H27N5OS2	1
1	IC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0527690 Compound Info	3-Amino-2-[4-[4-(7,8,9,10-tetrahydrophenanthridin-6-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one Show/Hide	C29H38N6O	1
1	IC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0531865 Compound Info	3-Amino-5,6-dimethyl-2-[3-[4-(3-phenylquinoxalin-2-yl)piperazin-1-yl]propylthio]-3H-thieno[2,3-d]pyrimidin-4-one Show/Hide	C29H31N7OS2	1
1	IC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0381751 Compound Info	3-[ethyl-[4-(5-fluoro-1H-indol-3-yl)butyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C24H27F2N3O2	2
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
2	Ki = 330 nM Bioactivity Info	TI LI LO TS
CP0375381 Compound Info	3-[[3-(7-Chloro-1H-indol-3-yl)propyl](cyclobutyl)amino]-8-fluorochromane-5-carboxamide Show/Hide	C25H27ClFN3O2	2
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
2	Ki = 26.1 nM Bioactivity Info	TI LI LO TS
CP0375387 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-ethyl-8-fluorochromane-5-carboxamide Show/Hide	C27H31F2N3O2	2
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
2	Ki = 17.8 nM Bioactivity Info	TI LI LO TS
CP0418502 Compound Info	3-{(Cyclopropylmethyl)[4-(4-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
2	Ki = 9.64 nM Bioactivity Info	TI LI LO TS
CP0424390 Compound Info	3-{Cyclobutyl[4-(5-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
2	Ki = 10.78 nM Bioactivity Info	TI LI LO TS
CP0456179 Compound Info	3-{Cyclobutyl[4-(7-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	2
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
2	Ki = 39.95 nM Bioactivity Info	TI LI LO TS
CP0461387 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-(cyclopropylmethyl)-8-fluorochromane-5-carboxamide Show/Hide	C29H33F2N3O2	2
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
2	Ki = 160.5 nM Bioactivity Info	TI LI LO TS
CP0484988 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-cyclopentyl-8-fluorochromane-5-carboxamide Show/Hide	C31H37F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0376227 Compound Info	N-cyclobutyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-3,4-dihydro-2H-chromen-3-amine Show/Hide	C25H29FN2O2	2
1	IC50 > 2000 nM Bioactivity Info	TI LI LO TS
2	Ki = 15.6 nM Bioactivity Info	TI LI LO TS
CP0399325 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N,N-dimethylchromane-5-carboxamide Show/Hide	C27H31F2N3O2	2
1	IC50 > 2000 nM Bioactivity Info	TI LI LO TS
2	Ki = 372 nM Bioactivity Info	TI LI LO TS
CP0401088 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxylic Acid Show/Hide	C25H26F2N2O3	1
1	IC50 > 2000 nM Bioactivity Info	TI LI LO TS
CP0441439 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-isopropylchromane-5-carboxamide Show/Hide	C28H33F2N3O2	2
1	IC50 > 2000 nM Bioactivity Info	TI LI LO TS
2	Ki = 46.1 nM Bioactivity Info	TI LI LO TS
CP0316443 Compound Info	N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine Show/Hide	C25H29NO5	1
1	Ki = 0.06761 nM Bioactivity Info	TI LI LO TS
CP0428171 Compound Info	(3S)-3-{(cyclopropylmethyl)[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	Ki = 0.1 nM Bioactivity Info	TI LI LO TS
CP0068074 Compound Info	6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine-3-carboxamide Show/Hide	C27H28N6O2	1
1	Ki = 0.1148 nM Bioactivity Info	TI LI LO TS
CP0397084 Compound Info	6-[2-[4-(2,7-dimethylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H28N4O2	1
1	Ki = 0.1259 nM Bioactivity Info	TI LI LO TS
CP0439314 Compound Info	8-[(3-Phenyl-propylamino)-methyl]-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester Show/Hide	C22H24N2O4	1
1	Ki = 0.2 nM Bioactivity Info	TI LI LO TS
CP0306958 Compound Info	(3aR,9bS) 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol Show/Hide	C15H21NO	1
1	Ki = 0.2 nM Bioactivity Info	TI LI LO TS
CP0780574 Compound Info	N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide tri hydrochloride Show/Hide	C25H35ClN4O2	1
1	Ki = 0.25 nM Bioactivity Info	TI LI LO TS
CP0344597 Compound Info	6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-4-propyl-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C28H34N4O3	2
1	Ki = 0.2512 nM Bioactivity Info	TI LI LO TS
2	Ki = 25.12 nM Bioactivity Info	TI LI LO TS
CP0873316 Compound Info	4-ethyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C28H33N3O3	2
1	Ki = 0.2512 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0218850 Compound Info	6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H26N4O2	1
1	Ki = 0.2512 nM Bioactivity Info	TI LI LO TS
CP0377437 Compound Info	6-[2-[4-(8-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25FN4O2	1
1	Ki = 0.2512 nM Bioactivity Info	TI LI LO TS
CP0427664 Compound Info	5-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25FN4O2	1
1	Ki = 0.2512 nM Bioactivity Info	TI LI LO TS
CP0465757 Compound Info	7-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25FN4O2	1
1	Ki = 0.2512 nM Bioactivity Info	TI LI LO TS
CP0391285 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-6-nitro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H24N2O5	1
1	Ki = 0.2884 nM Bioactivity Info	TI LI LO TS
CP0497002 Compound Info	8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid amide Show/Hide	C25H27N5O4	1
1	Ki = 0.3 nM Bioactivity Info	TI LI LO TS
CP0372726 Compound Info	(3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol Show/Hide	C15H19NO	1
1	Ki = 0.3 nM Bioactivity Info	TI LI LO TS
CP0492330 Compound Info	(1R,2R)-2-[4-(3,4-dihydro-2H-chromen-8-yl)piperidin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C23H26FNO2	1
1	Ki = 0.302 nM Bioactivity Info	TI LI LO TS
CP0152118 Compound Info	6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H29N3O3	2
1	Ki = 0.3162 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0422492 Compound Info	6-[2-[4-(7-chloro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25ClN4O2	1
1	Ki = 0.3162 nM Bioactivity Info	TI LI LO TS
CP0352267 Compound Info	(1R,3R,5S)-8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-(3-trifluoromethyl-phenyl)-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C24H26F3NO4	1
1	Ki = 0.33 nM Bioactivity Info	TI LI LO TS
CP0061623 Compound Info	8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione Show/Hide	C22H31N3O3	1
1	Ki = 0.3715 nM Bioactivity Info	TI LI LO TS
CP0296883 Compound Info	7-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H27F2N3O3	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0729034 Compound Info	4-methyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C27H31N3O3	2
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
2	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
CP0126585 Compound Info	4-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one Show/Hide	C25H28N4O2	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0397085 Compound Info	6-[2-[4-(2-methylquinazolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C23H25N5O2	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0040402 Compound Info	3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-oxazolidin-2-one Show/Hide	C25H28N4O2	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0040404 Compound Info	1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone Show/Hide	C25H29N5O	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0648464 Compound Info	Methyl(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)carbamate Show/Hide	C24H28N4O2	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0845523 Compound Info	4-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)-1,3-thiazole-5-carboxamide Show/Hide	C27H29N5OS	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0487023 Compound Info	8-(7,8-Dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalen-8-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one Show/Hide	C24H26N4O3	1
1	Ki = 0.4 nM Bioactivity Info	TI LI LO TS
CP0194021 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H24FNO3	1
1	Ki = 0.4365 nM Bioactivity Info	TI LI LO TS
CP0399663 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-6-methoxy-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H26N2O4	1
1	Ki = 0.4467 nM Bioactivity Info	TI LI LO TS
CP0464132 Compound Info	8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carbonitrile Show/Hide	C25H25N5O3	1
1	Ki = 0.5 nM Bioactivity Info	TI LI LO TS
CP0372019 Compound Info	7-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28FN3O3	1
1	Ki = 0.5012 nM Bioactivity Info	TI LI LO TS
CP0377439 Compound Info	4-ethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one Show/Hide	C26H30N4O2	1
1	Ki = 0.5012 nM Bioactivity Info	TI LI LO TS
CP0412307 Compound Info	6-[2-[4-(2,2-dimethyl-3H-1-benzofuran-7-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H29N3O3	1
1	Ki = 0.5012 nM Bioactivity Info	TI LI LO TS
CP0648465 Compound Info	N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-pyrazine Carboxamide Show/Hide	C27H28N6O	1
1	Ki = 0.5012 nM Bioactivity Info	TI LI LO TS
CP0688933 Compound Info	2-Methyl-5-(4-{2-[3-(1H-pyrazol-1-yl)phenyl]ethyl}-1-piperazinyl)quinoline Show/Hide	C25H27N5	1
1	Ki = 0.5012 nM Bioactivity Info	TI LI LO TS
CP0085020 Compound Info	N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-N-pyridin-2-ylcyclohexanecarboxamide Show/Hide	C25H31N3O	1
1	Ki = 0.51 nM Bioactivity Info	TI LI LO TS
CP0509789 Compound Info	(6R,7R)-6-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-6,7-dihydro-5H-cyclopenta[f][1,3]benzodioxol-7-ol Show/Hide	C23H25NO5	1
1	Ki = 0.5248 nM Bioactivity Info	TI LI LO TS
CP0420671 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-6-methyl-2,3-dihydro-1H-inden-1-ol Show/Hide	C23H27NO3	1
1	Ki = 0.5495 nM Bioactivity Info	TI LI LO TS
CP0374328 Compound Info	8-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-ylmethyl]-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester Show/Hide	C25H26N4O5	1
1	Ki = 0.6 nM Bioactivity Info	TI LI LO TS
CP0453486 Compound Info	8-(2-Hydroxymethyl-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalen-8-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one Show/Hide	C25H28N4O4	1
1	Ki = 0.6 nM Bioactivity Info	TI LI LO TS
CP0858844 Compound Info	4-isopropyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C29H35N3O3	2
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0433937 Compound Info	6-[4-[4-(2-methylquinolin-5-yl)piperazin-1-yl]butyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H30N4O2	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0422491 Compound Info	6-[2-[4-(2-phenylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C29H28N4O2	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0855716 Compound Info	3-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide Show/Hide	C29H29FN4O	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0398960 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H25NO3	1
1	Ki = 0.7079 nM Bioactivity Info	TI LI LO TS
CP0501571 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-6-nitro-2,3-dihydro-1H-inden-1-ol Show/Hide	C21H23N3O5	1
1	Ki = 0.7413 nM Bioactivity Info	TI LI LO TS
CP0453501 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-6-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H24FNO3	1
1	Ki = 0.7762 nM Bioactivity Info	TI LI LO TS
CP0108240 Compound Info	CAS_132787 Show/Hide	C21H24N2O2	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0507914 Compound Info	6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28FN3O3	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0291324 Compound Info	1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]piperazine Show/Hide	C24H24FN3O2	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0403061 Compound Info	6-[2-[3-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H28N4O2	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0040401 Compound Info	N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]methanesulfonamide Show/Hide	C23H28N4O2S	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0040416 Compound Info	2-methyl-N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-thiazole-4-carboxamide Show/Hide	C27H29N5OS	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0409421 Compound Info	N-[(2S)-1-[4-(4-chloro-1,2,5-thiadiazol-3-yl)piperazin-1-yl]-3-phenylpropan-2-yl]cyclohexanecarboxamide Show/Hide	C22H30ClN5OS	1
1	Ki = 0.8 nM Bioactivity Info	TI LI LO TS
CP0200359 Compound Info	(1R,3R,5S)-8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C27H29NO4	1
1	Ki = 0.81 nM Bioactivity Info	TI LI LO TS
CP0504873 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H23NO3	1
1	Ki = 0.8318 nM Bioactivity Info	TI LI LO TS
CP0087672 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H22FNO3	1
1	Ki = 0.8511 nM Bioactivity Info	TI LI LO TS
CP0375023 Compound Info	8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester Show/Hide	C26H28N4O5	1
1	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
CP0001212 Compound Info	1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine Show/Hide	C23H29N5OS	1
1	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
CP0401388 Compound Info	3-{[3-(5-Fluoro-1H-indol-3-yl)propyl](propyl)amino}chromane-5-carboxamide Show/Hide	C24H28FN3O2	1
1	Ki = 0.93 nM Bioactivity Info	TI LI LO TS
CP0441585 Compound Info	8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid benzyl ester Show/Hide	C32H32N4O5	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0461521 Compound Info	2-methyl-5-[2-[4-[[3-(4-methylpiperazin-1-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C29H38N4O	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0040398 Compound Info	N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]benzamide Show/Hide	C29H30N4O	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0040405 Compound Info	N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]acetamide Show/Hide	C24H28N4O	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0845521 Compound Info	2-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide Show/Hide	C29H29FN4O	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0393285 Compound Info	4-(5-fluoro-1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]cyclohexan-1-amine Show/Hide	C24H26FN3O	1
1	Ki = 1.08 nM Bioactivity Info	TI LI LO TS
CP0366912 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-6-methoxy-2,3-dihydro-1H-inden-1-ol Show/Hide	C23H27NO4	1
1	Ki = 1.096 nM Bioactivity Info	TI LI LO TS
CP0440048 Compound Info	N-[2-[4-(3,5-dimethylphenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C24H26N4O	1
1	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
CP0430929 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-5-methyl-2,3-dihydro-1H-inden-1-ol Show/Hide	C23H27NO3	1
1	Ki = 1.175 nM Bioactivity Info	TI LI LO TS
CP0378019 Compound Info	8-(4-Ethoxycarbonyl-piperidin-1-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester Show/Hide	C21H26N2O6	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0139060 Compound Info	N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-pyridin-2-ylcyclohexanecarboxamide Show/Hide	C24H32N4O	1
1	Ki = 1.21 nM Bioactivity Info	TI LI LO TS
CP0091710 Compound Info	4-butyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C29H36N4O3	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0146096 Compound Info	4-ethyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C27H32N4O3	2
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
2	Ki = 39.81 nM Bioactivity Info	TI LI LO TS
CP0216724 Compound Info	6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-4-phenethyl-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C33H36N4O3	2
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
2	Ki = 31.62 nM Bioactivity Info	TI LI LO TS
CP0422490 Compound Info	8-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25FN4O2	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0845530 Compound Info	4-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide Show/Hide	C29H29FN4O	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0866064 Compound Info	Ethyl(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate Show/Hide	C25H30N4O2	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0480617 Compound Info	(1R,2R)-2-[4-(3,4-dihydro-2H-chromen-8-yl)piperazin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H25FN2O2	1
1	Ki = 1.288 nM Bioactivity Info	TI LI LO TS
CP0391294 Compound Info	(1R,2R)-2-[4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C21H22ClFN2O3	1
1	Ki = 1.318 nM Bioactivity Info	TI LI LO TS
CP0534834 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-6-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C21H23FN2O3	1
1	Ki = 1.318 nM Bioactivity Info	TI LI LO TS
CP0203451 Compound Info	N-[(2R)-1-[4-(4-methoxy-1,2,5-thiadiazol-3-yl)piperazin-1-yl]-3-phenylpropan-2-yl]-N-methylcyclohexanecarboxamide Show/Hide	C24H35N5O2S	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0399743 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1-benzofuran-7-yl)piperidin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H24FNO2	1
1	Ki = 1.514 nM Bioactivity Info	TI LI LO TS
CP0207690 Compound Info	(1R,3R,5S)-8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-phenyl-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C23H27NO4	1
1	Ki = 1.53 nM Bioactivity Info	TI LI LO TS
CP0035199 Compound Info	5-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H27F2N3O3	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0495740 Compound Info	6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28ClN3O3	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0146095 Compound Info	4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C26H30N4O3	2
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
2	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0897868 Compound Info	6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C25H28N4O3	2
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
2	Ki = 63.1 nM Bioactivity Info	TI LI LO TS
CP0056386 Compound Info	5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one Show/Hide	C21H21ClN4OS	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0398938 Compound Info	6-[2-(4-quinolin-8-ylpiperazin-1-yl)ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C23H24N4O2	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0398939 Compound Info	6-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H28N4O2	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0855718 Compound Info	N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1-propanesulfonamide Show/Hide	C25H32N4O2S	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0431602 Compound Info	8-[(3-Phenyl-propylamino)-methyl]-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid (3-phenyl-propyl)-amide Show/Hide	C30H33N3O3	1
1	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0340053 Compound Info	(1R,3R,5S)-3-Benzo[b]thiophen-3-yl-8-((S)-8-methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C25H27NO4S	1
1	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0395651 Compound Info	N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylnaphthalene-2-carboxamide Show/Hide	C29H30N4O2	1
1	Ki = 1.61 nM Bioactivity Info	TI LI LO TS
CP0535416 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-2,3-dihydro-1H-inden-1-ol Show/Hide	C21H24N2O3	1
1	Ki = 1.622 nM Bioactivity Info	TI LI LO TS
CP0394623 Compound Info	N-(cyclopropylmethyl)-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-3,4-dihydro-2H-chromen-3-amine Show/Hide	C25H29FN2O2	1
1	Ki = 1.68 nM Bioactivity Info	TI LI LO TS
CP0245543 Compound Info	4-{trans-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin-1-yl}-1H-benzimidazole Show/Hide	C25H29N5	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0100452 Compound Info	(R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C23H21N	1
1	Ki = 1.8 nM Bioactivity Info	TI LI LO TS
CP0395694 Compound Info	N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylnaphthalene-1-carboxamide Show/Hide	C29H30N4O2	1
1	Ki = 1.89 nM Bioactivity Info	TI LI LO TS
CP0880810 Compound Info	4-isobutyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C29H36N4O3	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0461527 Compound Info	5-[2-[4-[[3-[(3S,5R)-3,5-dimethylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C30H40N4O	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0081200 Compound Info	1-ethyl-3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]urea Show/Hide	C25H31N5O	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0845520 Compound Info	2-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)propanamide Show/Hide	C26H32N4O	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0845529 Compound Info	N-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Acetamide Show/Hide	C25H30N4O	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0845559 Compound Info	3-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide Show/Hide	C30H32N4O2	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0864963 Compound Info	N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-propanamide Show/Hide	C25H30N4O	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0082953 Compound Info	2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride Show/Hide	C19H23NO5	1
1	Ki = 2.089 nM Bioactivity Info	TI LI LO TS
CP0492331 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-5,6-difluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C21H22F2N2O3	1
1	Ki = 2.138 nM Bioactivity Info	TI LI LO TS
CP0498082 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-5,6-difluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H23F2NO3	1
1	Ki = 2.188 nM Bioactivity Info	TI LI LO TS
CP0408328 Compound Info	N-ethyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-3,4-dihydro-2H-chromen-3-amine Show/Hide	C23H27FN2O2	1
1	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
CP0453958 Compound Info	N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylquinoxaline-2-carboxamide Show/Hide	C27H28N6O2	1
1	Ki = 2.48 nM Bioactivity Info	TI LI LO TS
CP0295528 Compound Info	6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-5-fluoro-4H-1,4-benzoxazin-3-one Show/Hide	C26H27ClFN3O3	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0332842 Compound Info	6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-7-fluoro-4H-1,4-benzoxazin-3-one Show/Hide	C26H27ClFN3O3	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0371946 Compound Info	5-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28FN3O3	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0177439 Compound Info	4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C27H31FN4O3	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0433939 Compound Info	6-[3-[4-(2-methylquinolin-5-yl)piperazin-1-yl]propyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H28N4O2	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0466838 Compound Info	2-(4-(4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)butyl)isoindoline-1,3-dione Show/Hide	C25H24FN3O2	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0403060 Compound Info	6-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25FN4O2	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0173138 Compound Info	N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]methanesulfonamide Show/Hide	C25H31N3O3S	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0382051 Compound Info	2-methyl-5-[2-[4-[[3-(4-methyl-1,4-diazepan-1-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C30H40N4O	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0388749 Compound Info	(2S,6R)-2,6-dimethyl-4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]morpholine Show/Hide	C30H39N3O2	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0453856 Compound Info	2-methyl-5-[2-[4-[[3-[(3R)-3-methylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C29H38N4O	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0845557 Compound Info	2-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide Show/Hide	C30H32N4O2	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0845558 Compound Info	3-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-tetrahydro-2H-1,3-oxazin-2-one Show/Hide	C26H30N4O2	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0861905 Compound Info	N-(4-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea Show/Hide	C29H30FN5O	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0488059 Compound Info	N-[2-[4-(3,5-difluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C22H20F2N4O	1
1	Ki = 2.62 nM Bioactivity Info	TI LI LO TS
CP0198989 Compound Info	3-[(1,4-trans)-4-(4-Quinolin-8-yl-piperazin-1-yl)-cyclohexyl]-1H-indole-5-carbonitrile Show/Hide	C28H29N5	1
1	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0235354 Compound Info	5-Methoxy-3-[trans-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C27H32N4O	1
1	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0280056 Compound Info	(1R,3R,5S)-8-((S)-8-Ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-(3-trifluoromethyl-phenyl)-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C25H28F3NO4	1
1	Ki = 2.92 nM Bioactivity Info	TI LI LO TS
CP0525986 Compound Info	8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid butyl ester Show/Hide	C29H34N4O5	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0308079 Compound Info	1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-methoxy-[1,2,5]thiadiazol-3-yl)-piperazin-1-yl]-1-pyridin-3-ylmethyl-ethyl}-amide Show/Hide	C23H34N6O2S	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0333034 Compound Info	4-{trans-4-[4-(1H-Indol-3-yl)cyclohexyl]piperazin-1-yl}-2-methyl-1H-benzimidazole Show/Hide	C26H31N5	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0163090 Compound Info	(1R,3R,5S)-8-((S)-8-Ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-phenyl-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C24H29NO4	1
1	Ki = 3.05 nM Bioactivity Info	TI LI LO TS
CP0177522 Compound Info	5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C26H29FN4O3	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0377438 Compound Info	6-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H28N4O2	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0397086 Compound Info	6-[2-[4-(2-methyl-1H-indol-4-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C23H26N4O2	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0374349 Compound Info	2-methyl-5-[2-[4-[[3-(1-methylpiperidin-4-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C30H39N3O	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0845522 Compound Info	1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-tetrahydro-2(1H)-pyrimidinone Show/Hide	C26H31N5O	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0845527 Compound Info	1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,5-pyrrolidinedione Show/Hide	C26H28N4O2	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0845556 Compound Info	N-(2-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea Show/Hide	C29H30FN5O	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0900503 Compound Info	4-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide Show/Hide	C30H32N4O2	1
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
CP0424391 Compound Info	(3S)-(+)-8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-chromane-5-carboxamide Show/Hide	C24H27F2N3O2	1
1	Ki = 3.2 nM Bioactivity Info	TI LI LO TS
CP0504914 Compound Info	N-[(2S)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl]-4-nitro-N-pyridin-2-ylbenzamide Show/Hide	C27H29N5O5	1
1	Ki = 3.4 nM Bioactivity Info	TI LI LO TS
CP0418491 Compound Info	8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-chromane-5-carboxamide Show/Hide	C24H27F2N3O2	1
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0270463 Compound Info	3-{4-[(1,4-trans)-4-(1H-indol-4-yl)-pipera-zinyl-1-yl]cyclohexyl}-1H-indole-5-carbonitrile Show/Hide	C27H29N5	1
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0158382 Compound Info	4-{trans-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin-1-yl}-2-(trifluoromethyl)-1H-benzimidazole Show/Hide	C26H28F3N5	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0411860 Compound Info	N-[2-[4-(3,5-dimethylphenyl)piperazin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C23H27N5O	1
1	Ki = 3.67 nM Bioactivity Info	TI LI LO TS
CP0385210 Compound Info	N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]quinoxaline-2-carboxamide Show/Hide	C22H22N4O	1
1	Ki = 3.76 nM Bioactivity Info	TI LI LO TS
CP0436932 Compound Info	(7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1-oxa-8-aza-dicyclopenta[a,h]naphthalene Show/Hide	C17H21NO	1
1	Ki = 3.9 nM Bioactivity Info	TI LI LO TS
CP0371948 Compound Info	8-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H27F2N3O3	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0201704 Compound Info	4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C32H34N4O3	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0412277 Compound Info	6-[2-[4-(8-chloro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25ClN4O2	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0377813 Compound Info	2-methyl-5-[2-[4-[[3-[(3S)-3-methylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C29H38N4O	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0377822 Compound Info	2-methyl-5-[2-[4-[(3-piperidin-1-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C29H37N3O	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0116805 Compound Info	1-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-3-phenylurea Show/Hide	C29H31N5O	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0861892 Compound Info	N-(3-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea Show/Hide	C29H30FN5O	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0447659 Compound Info	4-(2,4-difluorophenyl)-2-(2-(piperazin-1-yl)benzylidene)thiomorpholin-3-one Show/Hide	C21H21F2N3OS	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0129126 Compound Info	2-[4-[4-(6-bromopyridin-2-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C17H23BrN6O2	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0467025 Compound Info	N-[(2R)-1-[4-(4-chloro-1,2,5-thiadiazol-3-yl)piperazin-1-yl]-3-phenylpropan-2-yl]-N-methylcyclohexanecarboxamide Show/Hide	C23H32ClN5OS	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0334163 Compound Info	5-Fluoro-3-[trans-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C26H29FN4	1
1	Ki = 4.62 nM Bioactivity Info	TI LI LO TS
CP0490234 Compound Info	(1R,2R)-5-fluoro-2-[4-(6-fluoro-3,4-dihydro-2H-chromen-8-yl)piperidin-1-yl]-2,3-dihydro-1H-inden-1-ol Show/Hide	C23H25F2NO2	1
1	Ki = 4.898 nM Bioactivity Info	TI LI LO TS
CP0455390 Compound Info	(3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol Show/Hide	C15H19NO	1
1	Ki = 4.9 nM Bioactivity Info	TI LI LO TS
CP0430772 Compound Info	4-(2-(3-chlorophenoxy)phenyl)piperidine Show/Hide	C17H18ClNO	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0372020 Compound Info	8-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28FN3O3	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0407867 Compound Info	(R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazin-1-yl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C24H27FN4O2	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0377823 Compound Info	4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]morpholine Show/Hide	C28H35N3O2	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0417819 Compound Info	5-[2-[4-[[3-[(2S,5R)-2,5-dimethylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C30H40N4O	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0461524 Compound Info	2-methyl-5-[2-[4-[(3-pyridin-3-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C29H31N3O	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0845528 Compound Info	N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-N'-propylurea Show/Hide	C26H33N5O	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0377955 Compound Info	4-Chloro-N-{(S)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide Show/Hide	C27H29ClN4O3	1
1	Ki = 5.1 nM Bioactivity Info	TI LI LO TS
CP0518807 Compound Info	3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-5-carbonitrile Show/Hide	C25H23N3O2	1
1	Ki = 5.14 nM Bioactivity Info	TI LI LO TS
CP0199002 Compound Info	3-[trans-4-[4-(1H-Indol-4-yl)-1-pipera-zinyl]-cyclohexyl]-1H-indole Show/Hide	C26H30N4	1
1	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0333038 Compound Info	6-Fluoro-3-[trans-4-[4-(1H-indol-4-yl)-1-pipera-zinyl]cyclohexyl]-1H-indole Show/Hide	C26H29FN4	1
1	Ki = 5.4 nM Bioactivity Info	TI LI LO TS
CP0374997 Compound Info	3-{(Cyclopropylmethyl)[4-(5-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	Ki = 5.44 nM Bioactivity Info	TI LI LO TS
CP0506831 Compound Info	US9290463, B Show/Hide	C17H23IN6O2	1
1	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0453209 Compound Info	N-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C20H21FN2O3	1
1	Ki = 5.8 nM Bioactivity Info	TI LI LO TS
CP0219148 Compound Info	(1R,3R,5S)-8-((S)-8-Ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C28H31NO4	1
1	Ki = 5.87 nM Bioactivity Info	TI LI LO TS
CP0557554 Compound Info	US9290463, D Show/Hide	C18H24BrN5O2	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0436831 Compound Info	N,N-dipropyl-6,7,8,9-tetrahydrobenzo[g][1]benzofuran-8-amine Show/Hide	C18H25NO	1
1	Ki = 6.1 nM Bioactivity Info	TI LI LO TS
CP0556726 Compound Info	N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]naphthalene-2-carboxamide Show/Hide	C24H24N2O	1
1	Ki = 6.1 nM Bioactivity Info	TI LI LO TS
CP0333823 Compound Info	3-[(1,4-trans)-4-(4-Quinolin-5-yl-piperazin-1-yl)-cyclohexyl]-1H-indole-5-carbonitrile Show/Hide	C28H29N5	1
1	Ki = 6.2 nM Bioactivity Info	TI LI LO TS
CP0894510 Compound Info	[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-amine Show/Hide	C27H31NO3	1
1	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
CP0388729 Compound Info	2-methyl-5-[2-[4-[(3-piperidin-4-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C29H37N3O	1
1	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
CP0845526 Compound Info	2,2-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)propanamide Show/Hide	C27H34N4O	1
1	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
CP0854007 Compound Info	[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-chroman-2-ylmethyl)-amine Show/Hide	C26H29NO4	1
1	Ki = 6.457 nM Bioactivity Info	TI LI LO TS
CP0218896 Compound Info	8-{4-[(1,4-trans)-4-(5-Fluoro-1H-indol-3-yl)-cyclohexyl]-piperazin-1-yl}-quinoline Show/Hide	C27H29FN4	1
1	Ki = 6.5 nM Bioactivity Info	TI LI LO TS
CP0439150 Compound Info	8-Fluoro-3-[[4-(5-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	Ki = 6.54 nM Bioactivity Info	TI LI LO TS
CP0250914 Compound Info	2-(5-fluoro-1H-indol-3-yl)-N-((4-phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C25H24FN3O	1
1	Ki = 7.14 nM Bioactivity Info	TI LI LO TS
CP0308054 Compound Info	N-[(4-benzyl-2,3-dihydro-1,4-benzoxazin-2-yl)methyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C26H26FN3O	1
1	Ki = 7.25 nM Bioactivity Info	TI LI LO TS
CP0385212 Compound Info	N-[2-[4-(3,5-difluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C24H22F2N2O	1
1	Ki = 7.29 nM Bioactivity Info	TI LI LO TS
CP0339749 Compound Info	13-propyl-7-thia-5,13-diazapentacyclo[10.7.1.02,10.04,8.016,20]icosa-1(19),2,4(8),5,9,16(20),17-heptaen-6-amine Show/Hide	C20H21N3S	1
1	Ki = 7.5 nM Bioactivity Info	TI LI LO TS
CP0488058 Compound Info	N-[2-[4-(4-methylphenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C23H24N4O	1
1	Ki = 7.55 nM Bioactivity Info	TI LI LO TS
CP0847582 Compound Info	(+/-)-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine Show/Hide	C37H46N6O2	1
1	Ki = 7.59 nM Bioactivity Info	TI LI LO TS
CP0496803 Compound Info	N,N-dipropyl-6,7,8,9-tetrahydrobenzo[e][1]benzofuran-8-amine Show/Hide	C18H25NO	1
1	Ki = 7.8 nM Bioactivity Info	TI LI LO TS
CP0778798 Compound Info	3-{(1,4-trans)-4-[4-(1H-Indole-4-yl)-piperazin-1-yl]-cyclohexyl}-1H-pyrrolo[2,3-b]pyridine Show/Hide	C25H29N5	1
1	Ki = 7.8 nM Bioactivity Info	TI LI LO TS
CP0256818 Compound Info	4-{cis-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin-1-yl}-1H-benzimidazole Show/Hide	C25H29N5	1
1	Ki = 7.9 nM Bioactivity Info	TI LI LO TS
CP0146099 Compound Info	8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one Show/Hide	C26H29FN4O3	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0042927 Compound Info	7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one Show/Hide	C23H27Cl2N3O2	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0374348 Compound Info	1-methyl-4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperazin-2-one Show/Hide	C29H36N4O2	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0382035 Compound Info	2-methyl-5-[2-[4-[[3-(1-methylsulfonylpiperidin-4-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C30H39N3O3S	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0450459 Compound Info	2-methyl-5-[2-[4-[(3-pyridin-4-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C29H31N3O	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0855722 Compound Info	N-(1,1-Dimethylethyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea Show/Hide	C27H35N5O	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0373815 Compound Info	1-(2-(4-fluorophenoxy)phenyl)piperazine Show/Hide	C16H17FN2O	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0548574 Compound Info	N-[2-[4-(3,5-dimethylphenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C26H28N2O	1
1	Ki = 8.06 nM Bioactivity Info	TI LI LO TS
CP0395692 Compound Info	N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-N-pyridin-2-ylquinoxaline-2-carboxamide Show/Hide	C27H25N5O	1
1	Ki = 8.27 nM Bioactivity Info	TI LI LO TS
CP0341704 Compound Info	5-{4-[(1,4-trans)-4-(5-Fluoro-1H-indol-3-yl)-cyclohexyl]-piperazin-1-yl}-quinoline Show/Hide	C27H29FN4	1
1	Ki = 8.3 nM Bioactivity Info	TI LI LO TS
CP0453960 Compound Info	N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-N-pyridin-2-ylnaphthalene-2-carboxamide Show/Hide	C29H27N3O	1
1	Ki = 8.36 nM Bioactivity Info	TI LI LO TS
CP0499366 Compound Info	3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C24H24N2O2	1
1	Ki = 8.46 nM Bioactivity Info	TI LI LO TS
CP0435323 Compound Info	N-[(2S)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl]-N-pyridin-2-yl-4-(trifluoromethyl)benzamide Show/Hide	C28H29F3N4O3	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0439165 Compound Info	1-(2-(3-fluorophenoxy)phenyl)piperazine Show/Hide	C16H17FN2O	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0439215 Compound Info	4-(3,4-dichlorophenyl)-2-(2-(piperazin-1-yl)benzyl)thiomorpholin-3-one Show/Hide	C21H23Cl2N3OS	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0341702 Compound Info	3-[(1,4-trans)-4-(4-Quinoxalin-5-yl-piperazin-1-yl)-cyclohexyl]-1H-indole-5-carbonitrile Show/Hide	C27H28N6	1
1	Ki = 9.1 nM Bioactivity Info	TI LI LO TS
CP0374622 Compound Info	4-Cyano-N-{(S)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide Show/Hide	C28H29N5O3	1
1	Ki = 9.2 nM Bioactivity Info	TI LI LO TS
CP0548626 Compound Info	N-[2-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C22H21ClN4O	1
1	Ki = 9.3 nM Bioactivity Info	TI LI LO TS
CP0411285 Compound Info	3-(1-octylpyrrolidin-3-yl)phenol Show/Hide	C18H29NO	1
1	Ki = 9.4 nM Bioactivity Info	TI LI LO TS
CP0906113 Compound Info	(+/-)-11-((1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-4-yl)methoxy)-N-propylnoraporphine Show/Hide	C37H46N6O2	1
1	Ki = 9.68 nM Bioactivity Info	TI LI LO TS
CP0426023 Compound Info	N-[(2R)-1-[4-(4-methoxy-1,2,5-thiadiazol-3-yl)piperazin-1-yl]-3-phenylpropan-2-yl]-N-methylbenzamide Show/Hide	C24H29N5O2S	1
1	Ki = 9.9 nM Bioactivity Info	TI LI LO TS
CP0332841 Compound Info	6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-8-fluoro-4H-1,4-benzoxazin-3-one Show/Hide	C26H27ClFN3O3	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0388728 Compound Info	2-methyl-5-[2-[4-[(3-pyrrolidin-1-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C28H35N3O	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0499367 Compound Info	5-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C24H23FN2O2	1
1	Ki = 10.1 nM Bioactivity Info	TI LI LO TS
CP0869545 Compound Info	[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-thiochroman-2-ylmethyl)-amine Show/Hide	C26H29NO3S	1
1	Ki = 10.23 nM Bioactivity Info	TI LI LO TS
CP0512113 Compound Info	(1R,2R)-2-[4-[7-chloro-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-5-yl]piperazin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H24ClFN2O4	1
1	Ki = 10.47 nM Bioactivity Info	TI LI LO TS
CP0434735 Compound Info	8-Fluoro-3-[[4-(6-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	Ki = 10.6 nM Bioactivity Info	TI LI LO TS
CP0199001 Compound Info	4-{cis-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin-1-yl}-2-methyl-1H-benzimidazole Show/Hide	C26H31N5	1
1	Ki = 10.7 nM Bioactivity Info	TI LI LO TS
CP0892862 Compound Info	[2-(2-Benzyl-phenoxy)-ethyl]-[2-(2,6-dimethoxy-phenoxy)-ethyl]-amine Show/Hide	C25H29NO4	1
1	Ki = 10.72 nM Bioactivity Info	TI LI LO TS
CP0424389 Compound Info	(3R)-(-)-8-Fluoro-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propylchroman-3-amine Show/Hide	C24H28F2N2O2	1
1	Ki = 10.9 nM Bioactivity Info	TI LI LO TS
CP0861076 Compound Info	2-{[2-(2,6-Dimethoxy-phenoxy)-ethylamino]-methyl}-4-phenyl-3,4-dihydro-2H-naphthalen-1-one Show/Hide	C27H29NO4	1
1	Ki = 10.96 nM Bioactivity Info	TI LI LO TS
CP0401448 Compound Info	4-(2-(3-fluorophenoxy)phenyl)piperidine Show/Hide	C17H18FNO	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0488655 Compound Info	6-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C24H23FN2O2	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0470895 Compound Info	(E/Z)-11-(2-butenyloxy)-N-propylnoraporphine Show/Hide	C23H27NO	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0540568 Compound Info	N-[2-[4-(3,5-difluorophenyl)piperazin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C21H21F2N5O	1
1	Ki = 11.1 nM Bioactivity Info	TI LI LO TS
CP0409245 Compound Info	3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-cyclohexyl}-5-fluoro-1H-indole Show/Hide	C26H30FN3O2	1
1	Ki = 11.3 nM Bioactivity Info	TI LI LO TS
CP0492332 Compound Info	(1S,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C21H23FN2O3	1
1	Ki = 11.48 nM Bioactivity Info	TI LI LO TS
CP0488122 Compound Info	(1R,2R)-2-[4-(3,4-dihydro-2H-thiochromen-8-yl)-3,6-dihydro-2H-pyridin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C23H24FNOS	1
1	Ki = 11.75 nM Bioactivity Info	TI LI LO TS
CP0474888 Compound Info	11-Butyryloxy-N-n-propylnoraporphine Show/Hide	C23H27NO2	1
1	Ki = 11.9 nM Bioactivity Info	TI LI LO TS
CP0421900 Compound Info	(12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaen-18-ol Show/Hide	C20H21NO2	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0518040 Compound Info	3-(1-decylpyrrolidin-3-yl)phenol Show/Hide	C20H33NO	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0388750 Compound Info	1-[4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperidin-1-yl]ethanone Show/Hide	C31H39N3O2	1
1	Ki = 12.59 nM Bioactivity Info	TI LI LO TS
CP0375376 Compound Info	(3S)-(+)-8-Fluoro-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propylchroman-3-amine Show/Hide	C24H28F2N2O2	1
1	Ki = 12.6 nM Bioactivity Info	TI LI LO TS
CP0491184 Compound Info	3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-5-carbonitrile Show/Hide	C25H23N3O2	1
1	Ki = 12.7 nM Bioactivity Info	TI LI LO TS
CP0333824 Compound Info	3-[trans-4-[4-(1H-Indol-4-yl)-1-pipera-zinyl]-cyclohexyl]-2-methyl-1H-indole Show/Hide	C27H32N4	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0401087 Compound Info	8-Fluoro-3-[[4-(4-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0411858 Compound Info	N-[2-[4-(4-fluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C22H21FN4O	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0486966 Compound Info	N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-N-pyridin-2-ylnaphthalene-1-carboxamide Show/Hide	C29H27N3O	1
1	Ki = 14.01 nM Bioactivity Info	TI LI LO TS
CP0548895 Compound Info	5-Fluoro-3-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-cyclohexyl}-1H-indole Show/Hide	C25H30FN3O	1
1	Ki = 14.3 nM Bioactivity Info	TI LI LO TS
CP0531463 Compound Info	N-(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)butanamide Show/Hide	C23H28N2O	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0845244 Compound Info	[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-thiochroman-2-ylmethyl)-amine Show/Hide	C26H29NO3S	1
1	Ki = 15.14 nM Bioactivity Info	TI LI LO TS
CP0252376 Compound Info	N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propyl-3,4-dihydro-2H-chromen-3-amine Show/Hide	C24H29FN2O2	1
1	Ki = 15.8 nM Bioactivity Info	TI LI LO TS
CP0709961 Compound Info	3-{(1,4-cis)-4-[(1H-Indole-4-yl)-piperazin-1-yl]-cyclohexyl}-1H-pyrrolo[2,3-b]pyridine Show/Hide	C25H29N5	1
1	Ki = 15.8 nM Bioactivity Info	TI LI LO TS
CP0214664 Compound Info	2-(dimethylamino)-N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]acetamide Show/Hide	C28H36N4O2	1
1	Ki = 15.85 nM Bioactivity Info	TI LI LO TS
CP0861908 Compound Info	3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline Show/Hide	C22H26N4	1
1	Ki = 15.85 nM Bioactivity Info	TI LI LO TS
CP0877757 Compound Info	4-(6-fluoropyridin-2-yl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide Show/Hide	C27H31FN4O2	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0334162 Compound Info	4-{cis-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin-1-yl}-2-(trifluoromethyl)-1H-benzimidazole Show/Hide	C26H28F3N5	1
1	Ki = 16.1 nM Bioactivity Info	TI LI LO TS
CP0395649 Compound Info	N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-pyridin-2-ylnaphthalene-2-carboxamide Show/Hide	C28H28N4O	1
1	Ki = 16.29 nM Bioactivity Info	TI LI LO TS
CP0418500 Compound Info	8-Fluoro-3-[[4-(7-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	Ki = 16.6 nM Bioactivity Info	TI LI LO TS
CP0311103 Compound Info	(1R,3R,5S)-3-Benzo[b]thiophen-3-yl-8-((S)-8-ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C26H29NO4S	1
1	Ki = 16.7 nM Bioactivity Info	TI LI LO TS
CP0080064 Compound Info	(1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene Show/Hide	C20H21NO	1
1	Ki = 17.3 nM Bioactivity Info	TI LI LO TS
CP0375383 Compound Info	3-{Cyclobutyl[4-(4-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	Ki = 17.35 nM Bioactivity Info	TI LI LO TS
CP0535417 Compound Info	(1S,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-6-methoxy-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H26N2O4	1
1	Ki = 17.38 nM Bioactivity Info	TI LI LO TS
CP0377725 Compound Info	8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid Show/Hide	C25H26N4O5	1
1	Ki = 17.8 nM Bioactivity Info	TI LI LO TS
CP0086335 Compound Info	4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline Show/Hide	C27H30N4O2S2	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0485851 Compound Info	(S)-3-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C23H25F2N3O2	1
1	Ki = 18.6 nM Bioactivity Info	TI LI LO TS
CP0409253 Compound Info	N-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-4-(5-fluoro-1H-indol-3-yl)cyclohexan-1-amine Show/Hide	C24H27FN2O3	1
1	Ki = 18.9 nM Bioactivity Info	TI LI LO TS
CP0410364 Compound Info	8-chloro-5-[4-(2-phenylethyl)piperazin-1-yl]pyrido[2,3-b][1,5]benzoxazepine Show/Hide	C24H23ClN4O	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0405451 Compound Info	3-(1-heptylpyrrolidin-3-yl)phenol Show/Hide	C17H27NO	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0375385 Compound Info	8-Fluoro-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propylchroman-3-amine Show/Hide	C24H28F2N2O2	1
1	Ki = 19.4 nM Bioactivity Info	TI LI LO TS
CP0378357 Compound Info	6-[[1-[2-(8-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28FN3O3	1
1	Ki = 19.95 nM Bioactivity Info	TI LI LO TS
CP0464205 Compound Info	2-methyl-5-[2-[4-[(3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperidin-1-yl]ethoxy]quinoline-7-carbonitrile Show/Hide	C27H28N4O3	1
1	Ki = 19.95 nM Bioactivity Info	TI LI LO TS
CP0377812 Compound Info	4-methyl-1-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperazin-2-one Show/Hide	C29H36N4O2	1
1	Ki = 19.95 nM Bioactivity Info	TI LI LO TS
CP0438753 Compound Info	4-(3-fluoro-2-phenoxyphenyl)piperidine Show/Hide	C17H18FNO	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0881177 Compound Info	4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide Show/Hide	C27H31FN4O2	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0401481 Compound Info	4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine Show/Hide	C17H17F2NO	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0473635 Compound Info	N-[2-[4-(3,5-dimethylphenyl)piperazin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C25H29N3O	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0233039 Compound Info	N-(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)acetamide Show/Hide	C21H24N2O	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0375045 Compound Info	8-(4-Carbamoyl-4-phenylamino-piperidin-1-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester Show/Hide	C25H28N4O5	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0444016 Compound Info	2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenylpyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H32N4O2	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0218897 Compound Info	4-Fluoro-3-[trans-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C26H29FN4	1
1	Ki = 22.2 nM Bioactivity Info	TI LI LO TS
CP0523122 Compound Info	4-(5-fluoro-1H-indol-3-yl)-N-[2-(2-methoxyphenoxy)ethyl]cyclohexan-1-amine Show/Hide	C23H27FN2O2	1
1	Ki = 22.4 nM Bioactivity Info	TI LI LO TS
CP0492513 Compound Info	(1S,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H23NO3	1
1	Ki = 22.91 nM Bioactivity Info	TI LI LO TS
CP0133392 Compound Info	13-methyl-7-thia-5,13-diazapentacyclo[10.7.1.02,10.04,8.016,20]icosa-1(19),2,4(8),5,9,16(20),17-heptaen-6-amine Show/Hide	C18H17N3S	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0329733 Compound Info	N-(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)methanesulfonamide Show/Hide	C20H24N2O2S	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0476048 Compound Info	(1S,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-5-methoxy-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H26N2O4	1
1	Ki = 23.44 nM Bioactivity Info	TI LI LO TS
CP0488053 Compound Info	N-[2-(4-phenylpiperazin-1-yl)ethyl]naphthalene-2-carboxamide Show/Hide	C23H25N3O	1
1	Ki = 24.7 nM Bioactivity Info	TI LI LO TS
CP0448157 Compound Info	(1S,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H24FNO3	1
1	Ki = 26.92 nM Bioactivity Info	TI LI LO TS
CP0411859 Compound Info	N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C21H22ClN5O	1
1	Ki = 27 nM Bioactivity Info	TI LI LO TS
CP0443444 Compound Info	N-[2-[4-(4-methylphenyl)piperazin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C22H25N5O	1
1	Ki = 27.3 nM Bioactivity Info	TI LI LO TS
CP0373835 Compound Info	1-(2-(benzyloxy)phenyl)piperazine Show/Hide	C17H20N2O	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0546550 Compound Info	N-[2-[4-(3,5-difluorophenyl)piperazin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C23H23F2N3O	1
1	Ki = 28.95 nM Bioactivity Info	TI LI LO TS
CP0502638 Compound Info	(12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaene Show/Hide	C20H19NO	1
1	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0491190 Compound Info	3-(1-(2-(7-methoxybenzofuran-3-yl)propyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C25H26N2O2	1
1	Ki = 29.2 nM Bioactivity Info	TI LI LO TS
CP0487226 Compound Info	N-[2-(4-phenylpiperazin-1-yl)ethyl]quinoxaline-2-carboxamide Show/Hide	C21H23N5O	1
1	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0473266 Compound Info	6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-amine Show/Hide	C19H22N2	1
1	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0250473 Compound Info	2-(1H-indol-3-yl)-N-((4-phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)ethanamine Show/Hide	C25H25N3O	1
1	Ki = 30.21 nM Bioactivity Info	TI LI LO TS
CP0373802 Compound Info	1-(2-(2-fluorobenzyloxy)phenyl)piperazine Show/Hide	C17H19FN2O	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0385211 Compound Info	N-[2-[4-(4-methylphenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C25H26N2O	1
1	Ki = 31.6 nM Bioactivity Info	TI LI LO TS
CP0382052 Compound Info	5-[2-[4-[[3-(furan-3-yl)phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C28H30N2O2	1
1	Ki = 31.62 nM Bioactivity Info	TI LI LO TS
CP0235997 Compound Info	3-[cis-4-[4-(1H-Indol-4-yl)-1-piperazinyl]-cyclo-hexyl]-1H-indole Show/Hide	C26H30N4	1
1	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0279285 Compound Info	6-Fluoro-3-[cis-4-[4-(1H-indol-4-yl)-1-piperazinyl]cyclohexyl]-1H-indole Show/Hide	C26H29FN4	1
1	Ki = 33.5 nM Bioactivity Info	TI LI LO TS
CP0572341 Compound Info	N-[2-[4-(4-fluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C24H23FN2O	1
1	Ki = 33.5 nM Bioactivity Info	TI LI LO TS
CP0182849 Compound Info	(R)-7-Methyl-6a,7,8,9-tetrahydro-6H-1,7-diaza-benzo[cd]pyrene Show/Hide	C18H16N2	1
1	Ki = 33.9 nM Bioactivity Info	TI LI LO TS
CP0436564 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-[(3S)-dithiolan-3-yl]pentanoate Show/Hide	C27H33NO2S2	1
1	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0435989 Compound Info	N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-pyridin-2-ylnaphthalene-1-carboxamide Show/Hide	C28H28N4O	1
1	Ki = 35.85 nM Bioactivity Info	TI LI LO TS
CP0491182 Compound Info	3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C23H22N2O	1
1	Ki = 36.1 nM Bioactivity Info	TI LI LO TS
CP0453957 Compound Info	N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-pyridin-2-ylquinoxaline-2-carboxamide Show/Hide	C26H26N6O	1
1	Ki = 36.19 nM Bioactivity Info	TI LI LO TS
CP0245757 Compound Info	5-Fluoro-3-[cis-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C26H29FN4	1
1	Ki = 36.7 nM Bioactivity Info	TI LI LO TS
CP0453019 Compound Info	(3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole Show/Hide	C15H21N	1
1	Ki = 37 nM Bioactivity Info	TI LI LO TS
CP0245384 Compound Info	5-(Dimethylamino)-N-{4-[2-{4-[4-(1-naphthyl)piperazin-1-yl]butyl}-1,3-dioxotetrahydro-1H-pyrrolo[1,2-c]imidazol-7a(5H)-yl]butyl}naphthalene-1-sulfonamide Show/Hide	C40H50N6O4S	1
1	Ki = 38 nM Bioactivity Info	TI LI LO TS
CP0353453 Compound Info	(1R,3R,5S)-8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-(2-methoxy-phenyl)-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C24H29NO5	1
1	Ki = 39 nM Bioactivity Info	TI LI LO TS
CP0461737 Compound Info	6-[[1-[2-(8-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28ClN3O3	1
1	Ki = 39.81 nM Bioactivity Info	TI LI LO TS
CP0496867 Compound Info	2-methyl-5-[2-[4-[(4-methyl-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]quinoline Show/Hide	C24H28N4O3	1
1	Ki = 39.81 nM Bioactivity Info	TI LI LO TS
CP0502822 Compound Info	N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-methyl-3,4-dihydro-2H-chromen-3-amine Show/Hide	C22H25FN2O2	1
1	Ki = 40 nM Bioactivity Info	TI LI LO TS
CP0106069 Compound Info	6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene Show/Hide	C18H17N	1
1	Ki = 40.7 nM Bioactivity Info	TI LI LO TS
CP0473496 Compound Info	3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-5-carbonitrile Show/Hide	C24H20FN3O	1
1	Ki = 41.5 nM Bioactivity Info	TI LI LO TS
CP0530347 Compound Info	2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H34N4O3	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0548627 Compound Info	N-[2-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C24H23ClN2O	1
1	Ki = 42.5 nM Bioactivity Info	TI LI LO TS
CP0262701 Compound Info	5-Fluoro-3-[(1,4-trans)-4-(4-naphthalen-1-yl-piperazin-1-yl)-cyclohexyl]-1H-indole Show/Hide	C28H30FN3	1
1	Ki = 42.6 nM Bioactivity Info	TI LI LO TS
CP0235995 Compound Info	3-[(1,4-cis)-4-(4-Quinolin-8-yl-piperazin-1-yl)-cyclohexyl]-1H-indole-5-carbonitrile Show/Hide	C28H29N5	1
1	Ki = 43.9 nM Bioactivity Info	TI LI LO TS
CP0445317 Compound Info	(3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole Show/Hide	C15H21N	1
1	Ki = 44 nM Bioactivity Info	TI LI LO TS
CP0050995 Compound Info	(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol Show/Hide	C19H21NO	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0436454 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-[(3R)-dithiolan-3-yl]pentanoate Show/Hide	C27H33NO2S2	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0376225 Compound Info	(3R)-8-fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl]amino}chromane-5-carboxamide Show/Hide	C21H21F2N3O2	1
1	Ki = 45.2 nM Bioactivity Info	TI LI LO TS
CP0532730 Compound Info	(1R,3R,5S)-8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-pyridin-2-yl-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C22H26N2O4	1
1	Ki = 46 nM Bioactivity Info	TI LI LO TS
CP0463475 Compound Info	4-(4-fluorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H31FN4O2	1
1	Ki = 46 nM Bioactivity Info	TI LI LO TS
CP0162854 Compound Info	(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol Show/Hide	C16H25NO	1
1	Ki = 47 nM Bioactivity Info	TI LI LO TS
CP0396950 Compound Info	4-(2-(2-fluorobenzyloxy)phenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki = 47 nM Bioactivity Info	TI LI LO TS
CP0183414 Compound Info	(R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol Show/Hide	C17H17NO	1
1	Ki = 49 nM Bioactivity Info	TI LI LO TS
CP0339668 Compound Info	(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)urea Show/Hide	C18H19N3O	1
1	Ki = 49 nM Bioactivity Info	TI LI LO TS
CP0550796 Compound Info	4-(2-chlorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H31ClN4O2	1
1	Ki = 50 nM Bioactivity Info	TI LI LO TS
CP0513848 Compound Info	6-[[1-[2-(6-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H28FN3O3	1
1	Ki = 50.12 nM Bioactivity Info	TI LI LO TS
CP0423703 Compound Info	6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]azetidin-3-yl]methoxy]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25N3O4	1
1	Ki = 50.12 nM Bioactivity Info	TI LI LO TS
CP0412449 Compound Info	N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C23H24ClN3O	1
1	Ki = 50.7 nM Bioactivity Info	TI LI LO TS
CP0473106 Compound Info	4-(2-fluorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H31FN4O2	1
1	Ki = 53 nM Bioactivity Info	TI LI LO TS
CP0203262 Compound Info	3-{(1,4-trans)-4-[4-(1H-Indol-4-yl)-piperazin-1-yl]-cyclohexyl}-1-methyl-1H-indole-5-carbonitrile Show/Hide	C28H31N5	1
1	Ki = 53.2 nM Bioactivity Info	TI LI LO TS
CP0473634 Compound Info	N-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C23H24FN3O	1
1	Ki = 54.3 nM Bioactivity Info	TI LI LO TS
CP0421895 Compound Info	11-Propargyloxy-N-propylnoraporphine Show/Hide	C22H23NO	1
1	Ki = 55 nM Bioactivity Info	TI LI LO TS
CP0501490 Compound Info	3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C24H24N2O2	1
1	Ki = 56.3 nM Bioactivity Info	TI LI LO TS
CP0501492 Compound Info	3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-6-fluoro-1H-indole Show/Hide	C23H21FN2O	1
1	Ki = 56.3 nM Bioactivity Info	TI LI LO TS
CP0373805 Compound Info	4-(2-(2-fluoro-5-methylphenoxy)phenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki = 57 nM Bioactivity Info	TI LI LO TS
CP0377980 Compound Info	(+/-)-11-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-N-propylnoraporphine Show/Hide	C34H43N3O2	1
1	Ki = 58 nM Bioactivity Info	TI LI LO TS
CP0158381 Compound Info	3-[(1,4-cis)-4-(4-Quinolin-5-yl-piperazin-1-yl)-cyclohexyl]-1H-indole-5-carbonitrile Show/Hide	C28H29N5	1
1	Ki = 58.1 nM Bioactivity Info	TI LI LO TS
CP0158383 Compound Info	5-Chloro-3-[trans-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C26H29ClN4	1
1	Ki = 58.3 nM Bioactivity Info	TI LI LO TS
CP0123042 Compound Info	2-[4-[4-(4-iodophenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C18H24IN5O2	1
1	Ki = 58.3 nM Bioactivity Info	TI LI LO TS
CP0245542 Compound Info	5-Methoxy-3-[cis-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C27H32N4O	1
1	Ki = 60.3 nM Bioactivity Info	TI LI LO TS
CP0246708 Compound Info	(1R,3R,5S)-8-((S)-8-Ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-pyridin-2-yl-8-aza-bicyclo[3.2.1]octan-3-ol Show/Hide	C23H28N2O4	1
1	Ki = 61.6 nM Bioactivity Info	TI LI LO TS
CP0530348 Compound Info	2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C33H36N4O4	1
1	Ki = 62 nM Bioactivity Info	TI LI LO TS
CP0225451 Compound Info	(R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2,7-diaza-benzo[cd]pyrene Show/Hide	C18H16N2	1
1	Ki = 62.3 nM Bioactivity Info	TI LI LO TS
CP0439217 Compound Info	4-(2-phenoxyphenyl)piperidine Show/Hide	C17H19NO	1
1	Ki = 63 nM Bioactivity Info	TI LI LO TS
CP0444027 Compound Info	2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methylphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H34N4O2	1
1	Ki = 63 nM Bioactivity Info	TI LI LO TS
CP0404669 Compound Info	5-[2-[4-[(4-chloro-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C23H25ClN4O3	1
1	Ki = 63.1 nM Bioactivity Info	TI LI LO TS
CP0446420 Compound Info	2-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]-7H-1,2-benzoxazin-6-one Show/Hide	C25H28N4O3	1
1	Ki = 63.1 nM Bioactivity Info	TI LI LO TS
CP0388730 Compound Info	2-methyl-5-[2-[4-[(3-phenylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline Show/Hide	C30H32N2O	1
1	Ki = 63.1 nM Bioactivity Info	TI LI LO TS
CP0488057 Compound Info	N-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]quinoxaline-2-carboxamide Show/Hide	C21H22FN5O	1
1	Ki = 63.3 nM Bioactivity Info	TI LI LO TS
CP0394844 Compound Info	3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-cyclohexyl}-5-fluoro-1H-indole Show/Hide	C26H30FN3O2	1
1	Ki = 65.7 nM Bioactivity Info	TI LI LO TS
CP0417882 Compound Info	2-Methoxy-11-allyloxy-N-methylaporphine Show/Hide	C21H23NO2	1
1	Ki = 66 nM Bioactivity Info	TI LI LO TS
CP0389537 Compound Info	(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol Show/Hide	C19H21NO	1
1	Ki = 66 nM Bioactivity Info	TI LI LO TS
CP0499364 Compound Info	5-fluoro-3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C24H23FN2O2	1
1	Ki = 66.3 nM Bioactivity Info	TI LI LO TS
CP0539847 Compound Info	(1S,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-2,3-dihydro-1H-inden-1-ol Show/Hide	C21H24N2O3	1
1	Ki = 67.61 nM Bioactivity Info	TI LI LO TS
CP0538008 Compound Info	2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C33H36N4O4	1
1	Ki = 69 nM Bioactivity Info	TI LI LO TS
CP0090886 Compound Info	3-{4-[(1,4-cis)-4-(1H-Indol-4-yl)-pipera-zinyl-1-yl]-cyclohexyl}-1H-indole-5-carbonitrile Show/Hide	C27H29N5	1
1	Ki = 69.6 nM Bioactivity Info	TI LI LO TS
CP0333033 Compound Info	8-{4-[(1,4-cis)-4-(5-Fluoro-1H-indol-3-yl)-cyclohexyl]-piperazin-1-yl}-quinoline Show/Hide	C27H29FN4	1
1	Ki = 69.7 nM Bioactivity Info	TI LI LO TS
CP0941206 Compound Info	Paynantheine Show/Hide	C23H28N2O4	1
1	Ki = 71.8 nM Bioactivity Info	TI LI LO TS
CP0079318 Compound Info	1-(4-chlorophenyl)-4-[3-(4-fluorophenoxy)propyl]-1,4-diazepane Show/Hide	C20H24ClFN2O	1
1	Ki = 73 nM Bioactivity Info	TI LI LO TS
CP0424386 Compound Info	methyl 3-[cyclobutyl-[3-(5-fluoro-1H-indol-3-yl)propyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxylate Show/Hide	C26H28F2N2O3	1
1	Ki = 73.8 nM Bioactivity Info	TI LI LO TS
CP0034801 Compound Info	3-(1H-indol-3-yl)-N-((4-phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)propan-1-amine Show/Hide	C26H27N3O	1
1	Ki = 75.77 nM Bioactivity Info	TI LI LO TS
CP0373801 Compound Info	4-(2-(4-fluorobenzyloxy)phenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki = 77 nM Bioactivity Info	TI LI LO TS
CP0524324 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperidin-1-yl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-ol Show/Hide	C24H29NO5	1
1	Ki = 79.43 nM Bioactivity Info	TI LI LO TS
CP0404673 Compound Info	5-[2-[4-[(2,5-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C23H25Cl2N3O	1
1	Ki = 79.43 nM Bioactivity Info	TI LI LO TS
CP0433940 Compound Info	6-[[1-[3-(2-methylquinolin-5-yl)oxypropyl]azetidin-3-yl]methoxy]-4H-1,4-benzoxazin-3-one Show/Hide	C25H27N3O4	1
1	Ki = 79.43 nM Bioactivity Info	TI LI LO TS
CP0040250 Compound Info	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol Show/Hide	C21H25N3O2S	2
1	Ki = 79.43 nM Bioactivity Info	TI LI LO TS
2	Ki = 125 nM Bioactivity Info	TI LI LO TS
CP0044066 Compound Info	(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C17H17N	1
1	Ki = 80 nM Bioactivity Info	TI LI LO TS
CP0444022 Compound Info	2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33FN4O3	1
1	Ki = 80 nM Bioactivity Info	TI LI LO TS
CP0418174 Compound Info	(rac)-3-(3-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-o-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C36H46N6O3	1
1	Ki = 85 nM Bioactivity Info	TI LI LO TS
CP0778108 Compound Info	3-{8-[2-(3,4-Dihydro-benzo[c][1,2]dioxin-8-yloxy)-ethyl]-8-aza-bicyclo[3.2.1]oct-2-en-3-yl}-1H-indole Show/Hide	C25H26N2O3	1
1	Ki = 85.5 nM Bioactivity Info	TI LI LO TS
CP0389540 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] N-propylcarbamate Show/Hide	C23H28N2O2	1
1	Ki = 87 nM Bioactivity Info	TI LI LO TS
CP0341706 Compound Info	3-[cis-4-[4-(1H-Indol-4-yl)-1-piperazinyl]-cyclohexyl]-2-methyl-1H-indole Show/Hide	C27H32N4	1
1	Ki = 87.1 nM Bioactivity Info	TI LI LO TS
CP0387699 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] N-butylcarbamate Show/Hide	C24H30N2O2	1
1	Ki = 89 nM Bioactivity Info	TI LI LO TS
CP0235996 Compound Info	5-Fluoro-3-{trans-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl}-1-methyl-1H-indole Show/Hide	C27H31FN4	1
1	Ki = 90 nM Bioactivity Info	TI LI LO TS
CP0502640 Compound Info	(12R)-5,6-dimethyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene Show/Hide	C23H27NO	1
1	Ki = 90 nM Bioactivity Info	TI LI LO TS
CP0426137 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] N-benzylcarbamate Show/Hide	C27H28N2O2	1
1	Ki = 90 nM Bioactivity Info	TI LI LO TS
CP0077065 Compound Info	1-(4-chlorophenyl)-4-[4-(4-fluorophenyl)butyl]-1,4-diazepane Show/Hide	C21H26ClFN2	1
1	Ki = 91 nM Bioactivity Info	TI LI LO TS
CP0402226 Compound Info	2-(5-fluoro-1H-indol-3-yl)-N-[2-(5-fluoro-2-methoxyphenoxy)ethyl]ethanamine Show/Hide	C19H20F2N2O2	1
1	Ki = 91.4 nM Bioactivity Info	TI LI LO TS
CP0401233 Compound Info	(6aS)-1,2,10-trimethoxy-6-methyl-9-phenylmethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C27H29NO4	1
1	Ki = 92 nM Bioactivity Info	TI LI LO TS
CP0339750 Compound Info	13-propyl-4-thia-6,13-diazapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaen-5-amine Show/Hide	C20H21N3S	1
1	Ki = 93 nM Bioactivity Info	TI LI LO TS
CP0436511 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] N-ethylcarbamate Show/Hide	C22H26N2O2	1
1	Ki = 94 nM Bioactivity Info	TI LI LO TS
CP0915741 Compound Info	Speciogynine Show/Hide	C23H30N2O4	1
1	Ki = 95.5 nM Bioactivity Info	TI LI LO TS
CP0380688 Compound Info	[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] N-tert-butylcarbamate Show/Hide	C24H30N2O2	1
1	Ki = 96 nM Bioactivity Info	TI LI LO TS
CP0377633 Compound Info	4-[5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-indole-1-sulfonyl]-phenylamine Show/Hide	C20H21N3O3S	1
1	Ki = 97 nM Bioactivity Info	TI LI LO TS
CP0341705 Compound Info	5-{4-[(1,4-cis)-4-(5-Fluoro-1H-indol-3-yl)-cyclohexyl]-piperazin-1-yl}-quinoline Show/Hide	C27H29FN4	1
1	Ki = 97.2 nM Bioactivity Info	TI LI LO TS
CP0955381 Compound Info	9-O-desmethylpaynantheine Show/Hide	C22H26N2O4	1
1	Ki = 97.7 nM Bioactivity Info	TI LI LO TS
CP0439317 Compound Info	(rac)-3-(3-(1-(3-(4-(2-Hydroxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-o-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C35H44N6O3	1
1	Ki = 98 nM Bioactivity Info	TI LI LO TS
CP0025667 Compound Info	2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone Show/Hide	C18H19ClN4	2
1	Ki = 100 nM Bioactivity Info	TI LI LO TS
2	Ki = 101 nM Bioactivity Info	TI LI LO TS
CP0422489 Compound Info	6-[2-(4-isoquinolin-1-ylpiperazin-1-yl)ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C23H24N4O2	1
1	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0121280 Compound Info	7-[2-[2-(3-chlorophenyl)ethylamino]ethyl]quinolin-2-amine Show/Hide	C19H20ClN3	1
1	Ki < 100 nM Bioactivity Info	TI LI LO TS
CP0373807 Compound Info	1-(2-((2,3-difluorophenoxy)methyl)phenyl)piperazine Show/Hide	C17H18F2N2O	1
1	Ki = 101 nM Bioactivity Info	TI LI LO TS
CP0094971 Compound Info	(1S,5R)-3-(4-chlorophenyl)-8-[4-(4-fluorophenyl)butyl]-8-azabicyclo[3.2.1]octan-3-ol Show/Hide	C23H27ClFNO	1
1	Ki = 102 nM Bioactivity Info	TI LI LO TS
CP0481549 Compound Info	(6aS)-9-[(4-bromophenyl)methoxy]-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C27H28BrNO4	1
1	Ki = 102 nM Bioactivity Info	TI LI LO TS
CP0570086 Compound Info	2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methylphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H34N4O2	1
1	Ki = 102 nM Bioactivity Info	TI LI LO TS
CP0487227 Compound Info	2-[2-[4-(3,5-dimethylphenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]isoindole-1,3-dione Show/Hide	C23H24N2O2	1
1	Ki = 105 nM Bioactivity Info	TI LI LO TS
CP0278174 Compound Info	(S)-1-[3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]oct-2-en-8-yl]-3-(1H-indol-4-yloxy)-propan-2-ol Show/Hide	C24H24Cl2N2O2	1
1	Ki = 107 nM Bioactivity Info	TI LI LO TS
CP0179324 Compound Info	1H-4-indolyl 2-[3-(1H-3-indolyl)-8-azabicyclo[3.2.1]oct-2-en-8-yl]ethyl ether Show/Hide	C25H25N3O	1
1	Ki = 111.2 nM Bioactivity Info	TI LI LO TS
CP0393293 Compound Info	4-(6-Chloro-3-piperidin-4-yl-indole-1-sulfonyl)-phenylamine Show/Hide	C19H20ClN3O2S	1
1	Ki = 115 nM Bioactivity Info	TI LI LO TS
CP0418608 Compound Info	1-(2-((3-fluorophenoxy)methyl)phenyl)piperazine Show/Hide	C17H19FN2O	1
1	Ki = 116 nM Bioactivity Info	TI LI LO TS
CP0373819 Compound Info	4-(2-(4-fluorophenoxy)phenyl)piperidine Show/Hide	C17H18FNO	1
1	Ki = 117 nM Bioactivity Info	TI LI LO TS
CP0389272 Compound Info	(6aS)-1,2,10-trimethoxy-6-methyl-9-pentan-2-yloxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C25H33NO4	1
1	Ki = 117 nM Bioactivity Info	TI LI LO TS
CP0090894 Compound Info	4-Fluoro-3-[cis-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C26H29FN4	1
1	Ki = 117.3 nM Bioactivity Info	TI LI LO TS
CP0429840 Compound Info	((6S,7R)-6-Methyl-6,7,8,9-tetrahydro-naphtho[1,2-b]furan-7-yl)-dipropyl-amine Show/Hide	C19H27NO	1
1	Ki = 120 nM Bioactivity Info	TI LI LO TS
CP0373798 Compound Info	4-(2-(benzyloxy)phenyl)piperidine Show/Hide	C18H21NO	1
1	Ki = 121 nM Bioactivity Info	TI LI LO TS
CP0259806 Compound Info	(1S,5R)-3-(4-chlorophenyl)-8-[3-(4-fluorophenoxy)propyl]-8-azabicyclo[3.2.1]octan-3-ol Show/Hide	C22H25ClFNO2	1
1	Ki = 123 nM Bioactivity Info	TI LI LO TS
CP0341691 Compound Info	5-Fluoro-3-{cis-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl}-1-methyl-1H-indole Show/Hide	C27H31FN4	1
1	Ki = 124 nM Bioactivity Info	TI LI LO TS
CP0426136 Compound Info	(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl) N-naphthalen-1-ylcarbamate Show/Hide	C30H28N2O2	1
1	Ki = 124 nM Bioactivity Info	TI LI LO TS
CP0470891 Compound Info	11-(2-Butynyloxy)-N-propylnoraporphine Show/Hide	C23H25NO	1
1	Ki = 125 nM Bioactivity Info	TI LI LO TS
CP0398940 Compound Info	6-[2-[(1R,4R)-5-(2-methylquinolin-5-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H26N4O2	1
1	Ki = 125.89 nM Bioactivity Info	TI LI LO TS
CP0183907 Compound Info	5-Fluoro-1-[8-((S)-8-methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-2-en-3-yl]-1H-indole Show/Hide	C25H25FN2O3	1
1	Ki = 127.7 nM Bioactivity Info	TI LI LO TS
CP0373800 Compound Info	1-(2-phenoxyphenyl)piperazine Show/Hide	C16H18N2O	1
1	Ki = 128 nM Bioactivity Info	TI LI LO TS
CP0373837 Compound Info	4-(2-fluoro-6-phenoxyphenyl)piperidine Show/Hide	C17H18FNO	1
1	Ki = 128 nM Bioactivity Info	TI LI LO TS
CP0502815 Compound Info	5-Fluoro-3-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-cyclohexyl}-1H-indole Show/Hide	C25H30FN3O	1
1	Ki = 129 nM Bioactivity Info	TI LI LO TS
CP0562805 Compound Info	4-(2-fluorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33FN4O3	1
1	Ki = 130 nM Bioactivity Info	TI LI LO TS
CP0410365 Compound Info	8-chloro-5-(4-cyclohexylpiperazin-1-yl)pyrido[2,3-b][1,5]benzoxazepine Show/Hide	C22H25ClN4O	1
1	Ki = 131 nM Bioactivity Info	TI LI LO TS
CP0562807 Compound Info	2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H34N4O3	1
1	Ki = 132 nM Bioactivity Info	TI LI LO TS
CP0470625 Compound Info	(rac)-3-(3-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-m-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C36H46N6O3	1
1	Ki = 133 nM Bioactivity Info	TI LI LO TS
CP0341647 Compound Info	N-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)methanesulfonamide Show/Hide	C18H20N2O2S	1
1	Ki = 133 nM Bioactivity Info	TI LI LO TS
CP0417883 Compound Info	10-Allyl-11-hydroxy-N-methylaporphine Show/Hide	C20H21NO	1
1	Ki = 135 nM Bioactivity Info	TI LI LO TS
CP0532879 Compound Info	2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methylphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33FN4O2	1
1	Ki = 136 nM Bioactivity Info	TI LI LO TS
CP0853037 Compound Info	(+/-)-N-propylnoraporphin-11-yl-5-(1,2-dithiolan-3-yl)pentanoate Show/Hide	C27H33NO2S2	1
1	Ki = 137 nM Bioactivity Info	TI LI LO TS
CP0497908 Compound Info	(R)-2-(6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzene-1,3-diol Show/Hide	C23H21NO2	1
1	Ki = 139 nM Bioactivity Info	TI LI LO TS
CP0532878 Compound Info	2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33FN4O3	1
1	Ki = 140 nM Bioactivity Info	TI LI LO TS
CP0080056 Compound Info	(6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile Show/Hide	C25H22N2	1
1	Ki = 142 nM Bioactivity Info	TI LI LO TS
CP0417885 Compound Info	2-Methoxy-10-allyl-11-hydroxy-N-methylaporphine Show/Hide	C21H23NO2	1
1	Ki = 144 nM Bioactivity Info	TI LI LO TS
CP0393284 Compound Info	4-(5-fluoro-1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]cyclohexan-1-amine Show/Hide	C24H26FN3O	1
1	Ki = 147 nM Bioactivity Info	TI LI LO TS
CP0533299 Compound Info	2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-fluorophenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H30F2N4O2	1
1	Ki = 147 nM Bioactivity Info	TI LI LO TS
CP0430913 Compound Info	(R)-11-(3-methylbut-2-enyloxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C24H29NO	1
1	Ki = 149 nM Bioactivity Info	TI LI LO TS
CP0401234 Compound Info	(6aS)-9-hexan-2-yloxy-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C26H35NO4	1
1	Ki = 152 nM Bioactivity Info	TI LI LO TS
CP0433603 Compound Info	(6aS)-9-butoxy-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C24H31NO4	1
1	Ki = 153 nM Bioactivity Info	TI LI LO TS
CP0562806 Compound Info	4-(4-chlorophenyl)-2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H30ClFN4O2	1
1	Ki = 155 nM Bioactivity Info	TI LI LO TS
CP0373831 Compound Info	4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine Show/Hide	C17H17F2NO	1
1	Ki = 156 nM Bioactivity Info	TI LI LO TS
CP0333822 Compound Info	3-[(1,4-cis)-4-(4-Quinoxalin-5-yl-piperazin-1-yl)-cyclohexyl]-1H-indole-5-carbonitrile Show/Hide	C27H28N6	1
1	Ki = 156.2 nM Bioactivity Info	TI LI LO TS
CP0439878 Compound Info	5-[2-[4-(1H-benzimidazol-4-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C24H27N5O	1
1	Ki = 158.49 nM Bioactivity Info	TI LI LO TS
CP0433941 Compound Info	6-[1-[3-(2-methylquinolin-5-yl)oxypropyl]azetidin-3-yl]oxy-4H-1,4-benzoxazin-3-one Show/Hide	C24H25N3O4	1
1	Ki = 158.49 nM Bioactivity Info	TI LI LO TS
CP0389273 Compound Info	(6aS)-9-cyclohexyloxy-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C26H33NO4	1
1	Ki = 163 nM Bioactivity Info	TI LI LO TS
CP0409085 Compound Info	((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine Show/Hide	C18H29NO	1
1	Ki = 168 nM Bioactivity Info	TI LI LO TS
CP0078692 Compound Info	1-(4-chlorophenyl)-4-[3-(4-fluorophenyl)sulfanylpropyl]-1,4-diazepane Show/Hide	C20H24ClFN2S	1
1	Ki = 168 nM Bioactivity Info	TI LI LO TS
CP0074093 Compound Info	(R)-2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-2a,3,4,5-tetrahydrobenzo[cd]indol-2(1H)-one Show/Hide	C26H30N2O	1
1	Ki = 170 nM Bioactivity Info	TI LI LO TS
CP0873359 Compound Info	2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide Show/Hide	C20H22ClN3O2S	1
1	Ki = 170 nM Bioactivity Info	TI LI LO TS
CP0448769 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]propan-1-amine Show/Hide	C23H27FN2O	1
1	Ki = 170 nM Bioactivity Info	TI LI LO TS
CP0155744 Compound Info	(S)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C21H25NO4	1
1	Ki = 171 nM Bioactivity Info	TI LI LO TS
CP0277398 Compound Info	(S)-1-(1H-Indol-4-yloxy)-3-(3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-en-8-yl)-propan-2-ol Show/Hide	C28H28N2O2	1
1	Ki = 173.2 nM Bioactivity Info	TI LI LO TS
CP0563636 Compound Info	4-(2-chlorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33ClN4O3	1
1	Ki = 176 nM Bioactivity Info	TI LI LO TS
CP0118683 Compound Info	(R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-benzo[cd]pyren-1-one Show/Hide	C18H16N2O	1
1	Ki = 178 nM Bioactivity Info	TI LI LO TS
CP0400847 Compound Info	(6aS)-1,2,10-trimethoxy-6-methyl-9-pentoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C25H33NO4	1
1	Ki = 179 nM Bioactivity Info	TI LI LO TS
CP0367693 Compound Info	13-methyl-4-thia-6,13-diazapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaen-5-amine Show/Hide	C18H17N3S	1
1	Ki = 187 nM Bioactivity Info	TI LI LO TS
CP0419039 Compound Info	1-(2-(phenoxymethyl)phenyl)piperazine Show/Hide	C17H20N2O	1
1	Ki = 189 nM Bioactivity Info	TI LI LO TS
CP0500640 Compound Info	3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C23H21FN2O	1
1	Ki = 190 nM Bioactivity Info	TI LI LO TS
CP0548889 Compound Info	(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[4-(5-fluoro-1H-indol-3-yl)-cyclohexyl]-amine Show/Hide	C23H25FN2O2	1
1	Ki = 194 nM Bioactivity Info	TI LI LO TS
CP0391130 Compound Info	(3aS,9bS)-3,3a-dimethyl-5-phenyl-1,2,4,9b-tetrahydropyrrolo[2,3-c]quinoline Show/Hide	C19H22N2	1
1	Ki = 199.53 nM Bioactivity Info	TI LI LO TS
CP0426378 Compound Info	(3aS,9bS)-3,3a-dimethyl-6-phenyl-1,2,4,9b-tetrahydrochromeno[3,4-b]pyrrole Show/Hide	C19H21NO	1
1	Ki = 199.53 nM Bioactivity Info	TI LI LO TS
CP0426383 Compound Info	(3aS,9bS)-3a-methyl-6-phenyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole Show/Hide	C18H19NO	1
1	Ki = 199.53 nM Bioactivity Info	TI LI LO TS
CP0860616 Compound Info	3-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide Show/Hide	C20H22ClN3O2S	1
1	Ki = 200 nM Bioactivity Info	TI LI LO TS
CP0532880 Compound Info	2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenylpyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H31FN4O2	1
1	Ki = 209 nM Bioactivity Info	TI LI LO TS
CP0436719 Compound Info	N,N-dipropyl-6,7,8,9-tetrahydrobenzo[g][1]benzofuran-7-amine Show/Hide	C18H25NO	1
1	Ki = 210 nM Bioactivity Info	TI LI LO TS
CP0142787 Compound Info	2-[3-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]propyl]-1,3-benzothiazole Show/Hide	C21H24ClN3S	1
1	Ki = 216 nM Bioactivity Info	TI LI LO TS
CP0466071 Compound Info	(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl) N-tert-butylcarbamate Show/Hide	C24H30N2O2	1
1	Ki = 217 nM Bioactivity Info	TI LI LO TS
CP0890906 Compound Info	(6aR,S)-N-n-Propylnoraporphin-11-ylethylcarbamate Show/Hide	C22H26N2O2	1
1	Ki = 218 nM Bioactivity Info	TI LI LO TS
CP0563637 Compound Info	2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-fluorophenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H30F2N4O2	1
1	Ki = 218 nM Bioactivity Info	TI LI LO TS
CP0055840 Compound Info	13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene Show/Hide	C17H16ClN3O	1
1	Ki = 221 nM Bioactivity Info	TI LI LO TS
CP0480973 Compound Info	N-[2-[4-(4-methylphenyl)piperazin-1-yl]ethyl]naphthalene-2-carboxamide Show/Hide	C24H27N3O	1
1	Ki = 221.4 nM Bioactivity Info	TI LI LO TS
CP0504776 Compound Info	(6aS)-9-(cyclopropylmethoxy)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C24H29NO4	1
1	Ki = 224 nM Bioactivity Info	TI LI LO TS
CP0270462 Compound Info	3-{(1,4-cis)-4-[4-(1H-Indol-4-yl)-piperazin-1-yl]-cyclohexyl}-1-methyl-1H-indole-5-carbonitrile Show/Hide	C28H31N5	1
1	Ki = 232.9 nM Bioactivity Info	TI LI LO TS
CP0777252 Compound Info	2-Iodo-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide Show/Hide	C20H22IN3O2S	1
1	Ki = 234 nM Bioactivity Info	TI LI LO TS
CP0470410 Compound Info	(rac)-3-(3-(1-(3-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)-propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol Show/Hide	C36H43N7O2S	1
1	Ki = 235 nM Bioactivity Info	TI LI LO TS
CP0548641 Compound Info	(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)urea Show/Hide	C20H23N3O	1
1	Ki = 236 nM Bioactivity Info	TI LI LO TS
CP0389274 Compound Info	(6aS)-9-butan-2-yloxy-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C24H31NO4	1
1	Ki = 244 nM Bioactivity Info	TI LI LO TS
CP0452283 Compound Info	3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-5-fluoro-1H-indole Show/Hide	C23H21FN2O	1
1	Ki = 248 nM Bioactivity Info	TI LI LO TS
CP0397962 Compound Info	N-[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl]-5-(dithiolan-3-yl)pentanamide Show/Hide	C27H34N2OS2	1
1	Ki = 249 nM Bioactivity Info	TI LI LO TS
CP0039958 Compound Info	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one Show/Hide	C23H27FN4O2	1
1	Ki = 251.19 nM Bioactivity Info	TI LI LO TS
CP0233040 Compound Info	N,N-dimethyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-amine Show/Hide	C21H26N2	1
1	Ki = 256 nM Bioactivity Info	TI LI LO TS
CP0543896 Compound Info	4-(4-chlorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33ClN4O3	1
1	Ki = 257 nM Bioactivity Info	TI LI LO TS
CP0470894 Compound Info	(R)-(-)-2-methoxy-11-hydroxyaporphine Show/Hide	C18H19NO2	1
1	Ki = 258 nM Bioactivity Info	TI LI LO TS
CP0377684 Compound Info	(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl) N-propylcarbamate Show/Hide	C23H28N2O2	1
1	Ki = 258 nM Bioactivity Info	TI LI LO TS
CP0919252 Compound Info	(6aR,S)-N-n-Propylnoraporphin-11-ylbenzylcarbamate Show/Hide	C27H28N2O2	1
1	Ki = 259 nM Bioactivity Info	TI LI LO TS
CP0444020 Compound Info	2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenylpyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H34N4O3	1
1	Ki = 261 nM Bioactivity Info	TI LI LO TS
CP0077356 Compound Info	2-[4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]butyl]-1,3-benzothiazole Show/Hide	C22H26ClN3S	1
1	Ki = 263 nM Bioactivity Info	TI LI LO TS
CP0381740 Compound Info	(3R)-8-fluoro-3-[[3-(5-fluoro-1H-indol-3-yl)propyl](methyl)amino]chromane-5-carboxamide Show/Hide	C22H23F2N3O2	1
1	Ki = 266 nM Bioactivity Info	TI LI LO TS
CP0443940 Compound Info	5-(4-benzylpiperazin-1-yl)-8-chloropyrido[2,3-b][1,5]benzoxazepine Show/Hide	C23H21ClN4O	1
1	Ki = 266 nM Bioactivity Info	TI LI LO TS
CP0411284 Compound Info	3-(1-hexylpyrrolidin-3-yl)phenol Show/Hide	C16H25NO	1
1	Ki = 272 nM Bioactivity Info	TI LI LO TS
CP0380696 Compound Info	(6aS)-9-hexoxy-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C26H35NO4	1
1	Ki = 273 nM Bioactivity Info	TI LI LO TS
CP0212873 Compound Info	(1R,5S)-8-[4-(1,3-benzothiazol-2-yl)butyl]-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol Show/Hide	C24H27ClN2OS	1
1	Ki = 274 nM Bioactivity Info	TI LI LO TS
CP0426138 Compound Info	(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-amine Show/Hide	C19H22N2	1
1	Ki = 276 nM Bioactivity Info	TI LI LO TS
CP0426886 Compound Info	(R)-11-(allyloxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C22H25NO	1
1	Ki = 279 nM Bioactivity Info	TI LI LO TS
CP0564185 Compound Info	4-(4-fluorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33FN4O3	1
1	Ki = 281 nM Bioactivity Info	TI LI LO TS
CP0577067 Compound Info	4-(4-chlorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H31ClN4O2	1
1	Ki = 294 nM Bioactivity Info	TI LI LO TS
CP0953239 Compound Info	9-O-desmethylspeciogynine Show/Hide	C22H28N2O4	1
1	Ki = 294.1 nM Bioactivity Info	TI LI LO TS
CP0332973 Compound Info	4-[2-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-en-8-yl)-ethoxy]-1H-indole Show/Hide	C27H26N2O	1
1	Ki = 295 nM Bioactivity Info	TI LI LO TS
CP0042751 Compound Info	(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride Show/Hide	C17H17NO2	1
1	Ki = 296 nM Bioactivity Info	TI LI LO TS
CP0499276 Compound Info	5-fluoro-3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C23H20F2N2O	1
1	Ki = 300 nM Bioactivity Info	TI LI LO TS
CP0499365 Compound Info	6-fluoro-3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole Show/Hide	C24H23FN2O2	1
1	Ki = 303 nM Bioactivity Info	TI LI LO TS
CP0409246 Compound Info	4-(5-fluoro-1H-indol-3-yl)-N-[2-(2-methoxyphenoxy)ethyl]cyclohexan-1-amine Show/Hide	C23H27FN2O2	1
1	Ki = 307 nM Bioactivity Info	TI LI LO TS
CP0123788 Compound Info	8-[8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-2-en-3-yl]-quinoline Show/Hide	C26H26N2O3	1
1	Ki = 307.1 nM Bioactivity Info	TI LI LO TS
CP0156479 Compound Info	(+)-N-methyl-laurotetanine Show/Hide	C20H23NO4	1
1	Ki = 314 nM Bioactivity Info	TI LI LO TS
CP0237316 Compound Info	CHEMBL2058419 Show/Hide	C14H13BrN4O	1
1	Ki = 315 nM Bioactivity Info	TI LI LO TS
CP0527666 Compound Info	(1S,2R)-2-[4-(3,4-dihydro-2H-chromen-8-yl)piperazin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H25FN2O2	1
1	Ki = 316.23 nM Bioactivity Info	TI LI LO TS
CP0079263 Compound Info	2-methyl-5-[2-[4-(quinolin-8-ylmethyl)piperazin-1-yl]ethoxy]quinoline Show/Hide	C26H28N4O	1
1	Ki = 316.23 nM Bioactivity Info	TI LI LO TS
CP0465888 Compound Info	6-[2-[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H27N3O3	1
1	Ki = 316.23 nM Bioactivity Info	TI LI LO TS
CP0426421 Compound Info	(1S,2S)-1-ethyl-2-methyl-1,3-dihydrobenzo[f]chromen-2-amine Show/Hide	C16H19NO	1
1	Ki = 316.23 nM Bioactivity Info	TI LI LO TS
CP0458833 Compound Info	9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole Show/Hide	C21H25NO	1
1	Ki = 317 nM Bioactivity Info	TI LI LO TS
CP0332972 Compound Info	5-{2-[3-(1H-Indol-2-yl)-8-aza-bicyclo[3.2.1]oct-2-en-8-yl]-ethoxy}-quinoline Show/Hide	C26H25N3O	1
1	Ki = 320 nM Bioactivity Info	TI LI LO TS
CP0464019 Compound Info	(12R)-5-methyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaene Show/Hide	C22H23NO	1
1	Ki = 320 nM Bioactivity Info	TI LI LO TS
CP0279289 Compound Info	5-Chloro-3-[cis-4-[4-(1H-indol-4-yl)-1-piperazinyl]-cyclohexyl]-1H-indole Show/Hide	C26H29ClN4	1
1	Ki = 325.7 nM Bioactivity Info	TI LI LO TS
CP0470669 Compound Info	3-(1-pentylpyrrolidin-3-yl)phenol Show/Hide	C15H23NO	1
1	Ki = 326 nM Bioactivity Info	TI LI LO TS
CP0430207 Compound Info	(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[4-(5-fluoro-1H-indol-3-yl)-cyclohexyl]-amine Show/Hide	C23H25FN2O2	1
1	Ki = 332 nM Bioactivity Info	TI LI LO TS
CP0533297 Compound Info	2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methylphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C33H36N4O3	1
1	Ki = 333 nM Bioactivity Info	TI LI LO TS
CP0389578 Compound Info	benzyl 7-[4-(3-ethoxy-3-oxopropyl)piperazin-1-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylate Show/Hide	C26H33N3O4	1
1	Ki = 335 nM Bioactivity Info	TI LI LO TS
CP0464023 Compound Info	(12R)-5-methyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene Show/Hide	C22H25NO	1
1	Ki = 340 nM Bioactivity Info	TI LI LO TS
CP0103545 Compound Info	(-)-5-hydroxy-2-(dipropylamino)tetralin Show/Hide	C16H25NO	1
1	Ki = 344 nM Bioactivity Info	TI LI LO TS
CP0062900 Compound Info	(1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine Show/Hide	C18H18N2	1
1	Ki = 355 nM Bioactivity Info	TI LI LO TS
CP0168317 Compound Info	1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol Show/Hide	C28H27ClF5NO	1
1	Ki = 356 nM Bioactivity Info	TI LI LO TS
CP0332343 Compound Info	8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]oct-2-ene Show/Hide	C27H27NO3	1
1	Ki = 357 nM Bioactivity Info	TI LI LO TS
CP0433601 Compound Info	(6aS)-1,2,10-trimethoxy-6-methyl-9-prop-2-enoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C23H27NO4	1
1	Ki = 361 nM Bioactivity Info	TI LI LO TS
CP0439218 Compound Info	4-(2-(benzyloxy)-6-fluorophenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki = 364 nM Bioactivity Info	TI LI LO TS
CP0056108 Compound Info	(R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benzo[cd]pyren-2-one Show/Hide	C18H16N2O	1
1	Ki = 373 nM Bioactivity Info	TI LI LO TS
CP0447706 Compound Info	(R)-11-(2-methylallyloxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C23H27NO	1
1	Ki = 373 nM Bioactivity Info	TI LI LO TS
CP0420586 Compound Info	8-chloro-5-piperazin-1-ylpyrido[2,3-b][1,5]benzoxazepine Show/Hide	C16H15ClN4O	1
1	Ki = 375 nM Bioactivity Info	TI LI LO TS
CP0444024 Compound Info	2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methylphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C32H33FN4O2	1
1	Ki = 376 nM Bioactivity Info	TI LI LO TS
CP0570085 Compound Info	4-(2-chlorophenyl)-2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C31H30ClFN4O2	1
1	Ki = 378 nM Bioactivity Info	TI LI LO TS
CP0498739 Compound Info	N-[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl]butanamide Show/Hide	C23H28N2O	1
1	Ki = 380 nM Bioactivity Info	TI LI LO TS
CP0376634 Compound Info	N,N-diethyl-3-[1-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]triazol-4-yl]propan-1-amine Show/Hide	C23H38N6O	1
1	Ki = 381 nM Bioactivity Info	TI LI LO TS
CP0397961 Compound Info	(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl) N-butylcarbamate Show/Hide	C24H30N2O2	1
1	Ki = 385 nM Bioactivity Info	TI LI LO TS
CP0520838 Compound Info	N-[1-(cyclopropylmethoxy)-2-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl]methanesulfonamide Show/Hide	C23H28N2O4S	1
1	Ki = 385 nM Bioactivity Info	TI LI LO TS
CP0403124 Compound Info	5-[2-[4-(1H-indol-7-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C25H28N4O	1
1	Ki = 398.11 nM Bioactivity Info	TI LI LO TS
CP0436208 Compound Info	2-methyl-5-[2-[4-(quinolin-5-ylmethyl)piperazin-1-yl]ethoxy]quinoline Show/Hide	C26H28N4O	1
1	Ki = 398.11 nM Bioactivity Info	TI LI LO TS
CP0436211 Compound Info	5-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]quinazoline Show/Hide	C25H27N5O	1
1	Ki = 398.11 nM Bioactivity Info	TI LI LO TS
CP0495389 Compound Info	5-[2-[4-[(4-methoxy-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C24H28N4O4	1
1	Ki = 398.11 nM Bioactivity Info	TI LI LO TS
CP0465889 Compound Info	6-[[1-[2-(2-methylquinolin-5-yl)oxypropyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C27H31N3O3	1
1	Ki = 398.11 nM Bioactivity Info	TI LI LO TS
CP0562205 Compound Info	N-(2-methoxy-6-methyl-1-prop-2-enoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)methanesulfonamide Show/Hide	C22H26N2O4S	1
1	Ki = 403 nM Bioactivity Info	TI LI LO TS
CP0200874 Compound Info	2-[2-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]ethyl]-5-fluoro-2,3-dihydroinden-1-one Show/Hide	C22H24ClFN2O	1
1	Ki = 415 nM Bioactivity Info	TI LI LO TS
CP0414846 Compound Info	N-[(2S)-1-[4-(4-chloro-1,2,5-thiadiazol-3-yl)piperazin-1-yl]-3-phenylpropan-2-yl]pyridine-4-carboxamide Show/Hide	C21H23ClN6OS	1
1	Ki = 425 nM Bioactivity Info	TI LI LO TS
CP0473636 Compound Info	2-[2-[4-(3,5-difluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]isoindole-1,3-dione Show/Hide	C21H18F2N2O2	1
1	Ki = 425 nM Bioactivity Info	TI LI LO TS
CP0520823 Compound Info	N-[1-(cyclopropylmethoxy)-2-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl]butanamide Show/Hide	C26H32N2O3	1
1	Ki = 429 nM Bioactivity Info	TI LI LO TS
CP0439320 Compound Info	(rac)-3-(2-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)ethyl)-1-m-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C34H42N6O3	1
1	Ki = 457 nM Bioactivity Info	TI LI LO TS
CP0133391 Compound Info	N,N,6-trimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-amine Show/Hide	C19H22N2	1
1	Ki = 458 nM Bioactivity Info	TI LI LO TS
CP0414432 Compound Info	N-(2-methoxy-6-methyl-1-prop-2-enoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)butanamide Show/Hide	C25H30N2O3	1
1	Ki = 463 nM Bioactivity Info	TI LI LO TS
CP0438756 Compound Info	1-(2-((2-cyclopropylphenoxy)methyl)phenyl)piperazine Show/Hide	C20H24N2O	1
1	Ki = 466 nM Bioactivity Info	TI LI LO TS
CP0531466 Compound Info	N-(1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)butanamide Show/Hide	C23H28N2O3	1
1	Ki = 469 nM Bioactivity Info	TI LI LO TS
CP0532877 Compound Info	2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methylphenyl)pyrido[1,2-c]pyrimidine-1,3-dione Show/Hide	C33H36N4O3	1
1	Ki = 476 nM Bioactivity Info	TI LI LO TS
CP0082560 Compound Info	4-[4-chloro-3-(trifluoromethyl)phenyl]-1-(4,4-diphenylbutyl)piperidin-4-ol Show/Hide	C28H29ClF3NO	1
1	Ki = 481 nM Bioactivity Info	TI LI LO TS
CP0540180 Compound Info	N-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-4-(5-fluoro-1H-indol-3-yl)cyclohexan-1-amine Show/Hide	C24H27FN2O3	1
1	Ki = 484 nM Bioactivity Info	TI LI LO TS
CP0166862 Compound Info	1-(1,3-benzothiazol-2-yl)-5-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]pentan-1-one Show/Hide	C23H26ClN3OS	1
1	Ki = 495 nM Bioactivity Info	TI LI LO TS
CP0548629 Compound Info	2-[2-[4-(3,5-dimethylphenyl)piperazin-1-yl]ethyl]isoindole-1,3-dione Show/Hide	C22H25N3O2	1
1	Ki = 496 nM Bioactivity Info	TI LI LO TS
CP0404695 Compound Info	5-[2-[4-[(4-fluoro-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C23H25FN4O3	1
1	Ki = 501.19 nM Bioactivity Info	TI LI LO TS
CP0433938 Compound Info	6-[2-[4-[(2-methylquinolin-5-yl)oxymethyl]piperidin-1-yl]acetyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H27N3O4	1
1	Ki = 501.19 nM Bioactivity Info	TI LI LO TS
CP0415552 Compound Info	(6aS)-9-ethoxy-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C22H27NO4	1
1	Ki = 506 nM Bioactivity Info	TI LI LO TS
CP0502315 Compound Info	(12R)-5,6-dimethyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaene Show/Hide	C23H25NO	1
1	Ki = 510 nM Bioactivity Info	TI LI LO TS
CP0414433 Compound Info	N-(2-methoxy-6-methyl-1-prop-2-ynoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)methanesulfonamide Show/Hide	C22H24N2O4S	1
1	Ki = 511 nM Bioactivity Info	TI LI LO TS
CP0257640 Compound Info	CHEMBL1170237 Show/Hide	C14H13BrN4O	1
1	Ki = 527 nM Bioactivity Info	TI LI LO TS
CP0853639 Compound Info	2-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide Show/Hide	C19H20ClN3O2S	1
1	Ki = 552 nM Bioactivity Info	TI LI LO TS
CP0207579 Compound Info	(R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C25H25NO2	1
1	Ki = 554 nM Bioactivity Info	TI LI LO TS
CP0876333 Compound Info	(S)-9-Isopropoxy-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C23H29NO4	1
1	Ki = 563 nM Bioactivity Info	TI LI LO TS
CP0333036 Compound Info	1-Ethyl-3-{(1,4-cis)-4-[4-(1H-indol-4-yl)-piperazin-1-yl]-cyclohexyl}-1H-indole-5-carbonitrile Show/Hide	C29H33N5	1
1	Ki = 563.5 nM Bioactivity Info	TI LI LO TS
CP0419041 Compound Info	4-(2-(benzyloxy)-3-fluorophenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki = 606 nM Bioactivity Info	TI LI LO TS
CP0439161 Compound Info	8-(1-Buten-3-yl)-11-hydroxy-N-propylnoraporphine Show/Hide	C23H27NO	1
1	Ki = 626 nM Bioactivity Info	TI LI LO TS
CP0458990 Compound Info	(12R)-5,5-dimethyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene Show/Hide	C23H27NO	1
1	Ki = 630 nM Bioactivity Info	TI LI LO TS
CP0441452 Compound Info	6-[[4-(2-methylquinolin-5-yl)piperazin-1-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C23H24N4O2	1
1	Ki = 630.96 nM Bioactivity Info	TI LI LO TS
CP0391120 Compound Info	(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine Show/Hide	C14H21NO	1
1	Ki = 630.96 nM Bioactivity Info	TI LI LO TS
CP0556727 Compound Info	2-[2-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]isoindole-1,3-dione Show/Hide	C21H19ClN2O2	1
1	Ki = 631 nM Bioactivity Info	TI LI LO TS
CP0376633 Compound Info	(rac)-3-(3-(1-(3-(4-(Pyrimidin-2-yl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-m-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C33H42N8O2	1
1	Ki = 648 nM Bioactivity Info	TI LI LO TS
CP0531632 Compound Info	N-(2-methoxy-6-methyl-1-prop-2-ynoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)butanamide Show/Hide	C25H28N2O3	1
1	Ki = 661 nM Bioactivity Info	TI LI LO TS
CP0646694 Compound Info	SID50106001 Show/Hide	C17H20Cl2N2S	1
1	Ki = 673 nM Bioactivity Info	TI LI LO TS
CP0033479 Compound Info	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine Show/Hide	C17H19ClN2S	1
1	Ki = 673 nM Bioactivity Info	TI LI LO TS
CP0158384 Compound Info	3-{(1,4-cis)-4-[4-(1H-Indol-4-yl)-piperazin-1-yl]-cyclohexyl}-1-isopropyl-1H-indole-5-carbonitrile Show/Hide	C30H35N5	1
1	Ki = 694.2 nM Bioactivity Info	TI LI LO TS
CP0412450 Compound Info	2-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]isoindole-1,3-dione Show/Hide	C21H20N2O2	1
1	Ki = 706 nM Bioactivity Info	TI LI LO TS
CP0129619 Compound Info	N-[3-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide Show/Hide	C27H34N4O2S	1
1	Ki = 708 nM Bioactivity Info	TI LI LO TS
CP0233820 Compound Info	2-benzyl-6-(3-methoxyphenyl)-3,4-dihydro-1H-isoquinoline Show/Hide	C23H23NO	1
1	Ki = 733 nM Bioactivity Info	TI LI LO TS
CP0417884 Compound Info	10-Allyl-11-hydroxy-N-propylnoraporphine Show/Hide	C22H25NO	1
1	Ki = 793 nM Bioactivity Info	TI LI LO TS
CP0446421 Compound Info	4-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]-2-nitrophenol Show/Hide	C23H26N4O4	1
1	Ki = 794.33 nM Bioactivity Info	TI LI LO TS
CP0470409 Compound Info	(rac)-3-(3-(1-(3-(4-(Pyrimidin-2-yl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-o-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol Show/Hide	C33H42N8O2	1
1	Ki = 799 nM Bioactivity Info	TI LI LO TS
CP0138342 Compound Info	3-{(1,4-cis)-4-[4-(1H-Indol-4-yl)-piperazin-1-yl]-cyclohexyl}-1-propyl-1H-indole-5-carbonitrile Show/Hide	C30H35N5	1
1	Ki = 819.8 nM Bioactivity Info	TI LI LO TS
CP0066194 Compound Info	N-[2-(1,3-benzodioxol-5-yl)ethyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropan-1-amine Show/Hide	C28H33NO4	1
1	Ki = 821 nM Bioactivity Info	TI LI LO TS
CP0257261 Compound Info	1-Ethyl-3-{(1,4-trans)-4-[4-(1H-indol-4-yl)-piperazin-1-yl]-cyclohexyl}-1H-indole-5-carbonitrile Show/Hide	C29H33N5	1
1	Ki = 827.6 nM Bioactivity Info	TI LI LO TS
CP0415551 Compound Info	(6aS)-9-(2-fluoroethoxy)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C22H26FNO4	1
1	Ki = 845 nM Bioactivity Info	TI LI LO TS
CP0376224 Compound Info	1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole Show/Hide	C19H17FN2O2S	1
1	Ki = 875 nM Bioactivity Info	TI LI LO TS
CP0198449 Compound Info	4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[5-(4-fluorophenyl)pentyl]piperidin-4-ol Show/Hide	C23H26ClF4NO	1
1	Ki = 901 nM Bioactivity Info	TI LI LO TS
CP0367684 Compound Info	(2-methoxy-6-methyl-1-prop-2-ynoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)urea Show/Hide	C22H23N3O3	1
1	Ki = 911 nM Bioactivity Info	TI LI LO TS
CP0281205 Compound Info	(+/-)-9-iso-butyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C27H32FN3O2	1
1	Ki = 927 nM Bioactivity Info	TI LI LO TS
CP0336108 Compound Info	(+/-)-9-((3-(5-fluoro-1H-indol-3-yl)propyl)(3,3,3-trifluoropropyl)amino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one Show/Hide	C26H27F4N3O2	1
1	Ki = 966 nM Bioactivity Info	TI LI LO TS
CP0439874 Compound Info	5-[2-[4-(1H-indol-5-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C25H28N4O	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0391154 Compound Info	(3aS,9bS)-7,9-dimethoxy-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole Show/Hide	C14H19NO3	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0426384 Compound Info	(3aS,9bS)-6-bromo-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole Show/Hide	C12H14BrNO	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0314578 Compound Info	4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-fluoro-N-(4-fluorophenyl)anilino)butyl]piperidin-4-ol Show/Hide	C28H28ClF5N2O	1
1	Ki = 1094 nM Bioactivity Info	TI LI LO TS
CP0438748 Compound Info	4-(2-(3,4-dichlorobenzyloxy)-5-fluorophenyl)piperidine Show/Hide	C18H18Cl2FNO	1
1	Ki = 1160 nM Bioactivity Info	TI LI LO TS
CP0064183 Compound Info	4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine Show/Hide	C21H16N4O2	1
1	Ki = 1200 nM Bioactivity Info	TI LI LO TS
CP0073146 Compound Info	benzyl 7-(4-cyclopentylpiperazin-1-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylate Show/Hide	C26H33N3O2	1
1	Ki = 1201 nM Bioactivity Info	TI LI LO TS
CP0345078 Compound Info	(+/-)-N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-(1-oxo-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-9-yl)benzamide Show/Hide	C30H28FN3O3	1
1	Ki = 1220 nM Bioactivity Info	TI LI LO TS
CP0069223 Compound Info	4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[3-(4-fluoro-N-(4-fluorophenyl)anilino)propyl]piperidin-4-ol Show/Hide	C27H26ClF5N2O	1
1	Ki = 1262 nM Bioactivity Info	TI LI LO TS
CP0540236 Compound Info	[1-(cyclopropylmethoxy)-2-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl]urea Show/Hide	C23H27N3O3	1
1	Ki = 1280 nM Bioactivity Info	TI LI LO TS
CP0003459 Compound Info	3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane Show/Hide	C28H37N5OS	1
1	Ki = 1297 nM Bioactivity Info	TI LI LO TS
CP0154285 Compound Info	1-[5,5-bis(4-fluorophenyl)pent-4-enyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol Show/Hide	C29H27ClF5NO	1
1	Ki = 1363 nM Bioactivity Info	TI LI LO TS
CP0198450 Compound Info	1-[5,5-bis(4-fluorophenyl)pentyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol Show/Hide	C29H29ClF5NO	1
1	Ki = 1395 nM Bioactivity Info	TI LI LO TS
CP0531462 Compound Info	1-(cyclopropylmethoxy)-2-methoxy-N,N,6-trimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-amine Show/Hide	C24H30N2O2	1
1	Ki = 1440 nM Bioactivity Info	TI LI LO TS
CP0525861 Compound Info	N-[1-(cyclopropylmethoxy)-2-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl]acetamide Show/Hide	C24H28N2O3	1
1	Ki = 1540 nM Bioactivity Info	TI LI LO TS
CP0414434 Compound Info	1,2-dimethoxy-N,N,6-trimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-amine Show/Hide	C21H26N2O2	1
1	Ki = 1570 nM Bioactivity Info	TI LI LO TS
CP0376998 Compound Info	4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-sulfonyl]-phenylamine Show/Hide	C19H19N3O2S	1
1	Ki = 1670 nM Bioactivity Info	TI LI LO TS
CP0405450 Compound Info	3-(1-butylpyrrolidin-3-yl)phenol Show/Hide	C14H21NO	1
1	Ki = 1805 nM Bioactivity Info	TI LI LO TS
CP0146889 Compound Info	CHEMBL2058420 Show/Hide	C14H13BrN4O	1
1	Ki = 1812 nM Bioactivity Info	TI LI LO TS
CP0391121 Compound Info	(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine Show/Hide	C13H19NO	1
1	Ki = 1995.26 nM Bioactivity Info	TI LI LO TS
CP0437998 Compound Info	(3S,4S)-4-ethyl-3-methyl-6-phenyl-2,4-dihydrochromen-3-amine Show/Hide	C18H21NO	1
1	Ki = 1995.26 nM Bioactivity Info	TI LI LO TS
CP0248165 Compound Info	2-benzyl-5-(3-methoxyphenyl)-1,3-dihydroisoindole Show/Hide	C22H21NO	1
1	Ki = 2019 nM Bioactivity Info	TI LI LO TS
CP0137322 Compound Info	1H-indol-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone Show/Hide	C22H25N3O3	1
1	Ki = 2108 nM Bioactivity Info	TI LI LO TS
CP0225367 Compound Info	benzyl 5-(4-cyclopentylpiperazin-1-yl)-1,3-dihydroisoindole-2-carboxylate Show/Hide	C25H31N3O2	1
1	Ki = 2135 nM Bioactivity Info	TI LI LO TS
CP0418657 Compound Info	4-(5-fluoro-2-(4-fluorobenzyloxy)phenyl)piperidine Show/Hide	C18H19F2NO	1
1	Ki = 2210 nM Bioactivity Info	TI LI LO TS
CP0369306 Compound Info	4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine Show/Hide	C21H12F3N3O2	1
1	Ki = 2500 nM Bioactivity Info	TI LI LO TS
CP0421273 Compound Info	(3S,4S)-4-ethyl-6-methoxy-3-methyl-2,4-dihydrochromen-3-amine Show/Hide	C13H19NO2	1
1	Ki = 2511.89 nM Bioactivity Info	TI LI LO TS
CP0455600 Compound Info	(3S,4S)-4-ethyl-3-methyl-2,4-dihydrobenzo[h]chromen-3-amine Show/Hide	C16H19NO	1
1	Ki = 2511.89 nM Bioactivity Info	TI LI LO TS
CP0210541 Compound Info	CHEMBL2058427 Show/Hide	C15H15BrN4O	1
1	Ki = 2513 nM Bioactivity Info	TI LI LO TS
CP0335097 Compound Info	benzyl 5-(4-methylpiperazin-1-yl)-1,3-dihydroisoindole-2-carboxylate Show/Hide	C21H25N3O2	1
1	Ki = 2609 nM Bioactivity Info	TI LI LO TS
CP0092225 Compound Info	CHEMBL2058416 Show/Hide	C14H13BrN4O	1
1	Ki = 2624 nM Bioactivity Info	TI LI LO TS
CP0114037 Compound Info	CHEMBL2058695 Show/Hide	C12H8BrN3OS	1
1	Ki = 2753 nM Bioactivity Info	TI LI LO TS
CP0124957 Compound Info	CHEMBL1173331 Show/Hide	C13H11BrN4O	1
1	Ki = 3215 nM Bioactivity Info	TI LI LO TS
CP0860580 Compound Info	(E)-5-((4-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one Show/Hide	C13H11BrN4O	1
1	Ki = 3445 nM Bioactivity Info	TI LI LO TS
CP0244206 Compound Info	7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine Show/Hide	C21H12F3N3OS	1
1	Ki = 3700 nM Bioactivity Info	TI LI LO TS
CP0237330 Compound Info	(3aS,6R,6aS,9aR,9bR)-6-ethyl-1-propyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one Show/Hide	C17H29NO	1
1	Ki = 4500 nM Bioactivity Info	TI LI LO TS
CP0237317 Compound Info	CHEMBL2058415 Show/Hide	C14H13BrN4O	1
1	Ki = 4608 nM Bioactivity Info	TI LI LO TS
CP0117807 Compound Info	4-[4-[1-[4-[1-(6-aminohexyl)triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid Show/Hide	C41H46F3N5O2	1
1	Ki = 5650 nM Bioactivity Info	TI LI LO TS
CP0135923 Compound Info	CHEBI:6956 Show/Hide	C23H30N2O4	1
1	Ki = 5880 nM Bioactivity Info	TI LI LO TS
CP0127400 Compound Info	(-)-Pramipexole Show/Hide	C10H17N3S	1
1	Ki = 6514 nM Bioactivity Info	TI LI LO TS
CP0064188 Compound Info	4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine Show/Hide	C21H13F3N4O2	1
1	Ki = 6900 nM Bioactivity Info	TI LI LO TS
CP0114039 Compound Info	CHEMBL2058426 Show/Hide	C15H15BrN4O	1
1	Ki = 6927 nM Bioactivity Info	TI LI LO TS
CP0886656 Compound Info	(E)-5-((7-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one Show/Hide	C13H11BrN4O	1
1	Ki = 7269 nM Bioactivity Info	TI LI LO TS
CP0866621 Compound Info	(E)-5-((5-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one Show/Hide	C13H11BrN4O	1
1	Ki = 7361 nM Bioactivity Info	TI LI LO TS
CP0096286 Compound Info	(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol Show/Hide	C18H28N2O3S	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0492308 Compound Info	(R)-Trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester Show/Hide	C25H19F6NO6S2	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0433950 Compound Info	6-[2-[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]acetyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H25N3O4	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0526143 Compound Info	6-[[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C24H25N3O3	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0421902 Compound Info	10-(2-Butenyl)-11-hydroxy-N-propylnoraporphine Show/Hide	C23H27NO	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0464021 Compound Info	11-(1-Methylallyloxy)-N-methylaporphine Show/Hide	C23H27NO	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0635067 Compound Info	2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride Show/Hide	C8H9Cl2N3	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0055735 Compound Info	5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dimethyl-imidazolidin-4-one Show/Hide	C14H13BrN4O	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0114041 Compound Info	CHEMBL2058429 Show/Hide	C15H15BrN4O	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0114042 Compound Info	5-[(6-bromoindol-3-ylidene)methyl]-1,3-dimethyl-2-methyliminoimidazol-4-ol Show/Hide	C15H15BrN4O	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0146890 Compound Info	CHEMBL2058418 Show/Hide	C14H13BrN4O	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0253203 Compound Info	(E)-5-((1H-Indol-3yl)methylene)-2-imino-1,3-dimethylimidazolidin-4-one Show/Hide	C14H14N4O	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0787573 Compound Info	(E)-5-((6-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one Show/Hide	C13H11BrN4O	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0054519 Compound Info	(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene Show/Hide	C25H31F3N2	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0085414 Compound Info	(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one Show/Hide	C20H27NO	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0202831 Compound Info	4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-methoxy-N-(4-methoxyphenyl)anilino)butyl]piperidin-4-ol Show/Hide	C30H34ClF3N2O3	1
1	Ki = 10000 nM Bioactivity Info	TI LI LO TS
CP0387083 Compound Info	(3aS,9bS)-3a-methyl-5-phenyl-2,3,4,9b-tetrahydro-1H-pyrrolo[2,3-c]quinoline Show/Hide	C18H20N2	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0285377 Compound Info	(3aS,9bR)-6-methoxy-3-prop-2-enyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indole Show/Hide	C16H21NO	1
1	Ki > 333 nM Bioactivity Info	TI LI LO TS
CP0448489 Compound Info	9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole Show/Hide	C21H25NO	1
1	Ki > 442 nM Bioactivity Info	TI LI LO TS
CP0376875 Compound Info	4-(2,3-dihydro-1,4-benzodioxin-5-yl)-1-[(1R,2R)-5-fluoro-1-hydroxy-2,3-dihydro-1H-inden-2-yl]piperidin-4-ol Show/Hide	C22H24FNO4	1
1	Ki < 1000 nM Bioactivity Info	TI LI LO TS
CP0406212 Compound Info	4-(2,3-dihydro-1,4-benzodioxin-5-yl)-1-[(1S,2R)-5-fluoro-1-hydroxy-2,3-dihydro-1H-inden-2-yl]piperidin-4-ol Show/Hide	C22H24FNO4	1
1	Ki < 1000 nM Bioactivity Info	TI LI LO TS
CP0416583 Compound Info	6-Chloro-3-methyl-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide Show/Hide	C18H20ClNO2	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0373806 Compound Info	4-(2-((3-fluorophenoxy)methyl)phenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0439216 Compound Info	4-(5-chloro-2-(4-fluorobenzyloxy)phenyl)piperidine Show/Hide	C18H19ClFNO	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0472699 Compound Info	4-(2-(phenoxymethyl)phenyl)piperidine Show/Hide	C18H21NO	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0399848 Compound Info	2-amino-4-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]phenol Show/Hide	C23H28N4O2	1
1	Ki < 1258.93 nM Bioactivity Info	TI LI LO TS
CP0433935 Compound Info	6-[[4-[(2-methylquinolin-5-yl)oxymethyl]piperidin-1-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C25H27N3O3	1
1	Ki > 1584.89 nM Bioactivity Info	TI LI LO TS
CP0409239 Compound Info	1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole Show/Hide	C19H17ClN2O2S	1
1	Ki > 2000 nM Bioactivity Info	TI LI LO TS
CP0373799 Compound Info	4-(2-(4-fluorophenoxy)-4-methylphenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki > 4570 nM Bioactivity Info	TI LI LO TS
CP0373840 Compound Info	4-(4,5-difluoro-2-(4-fluorophenoxy)phenyl)piperidine Show/Hide	C17H16F3NO	1
1	Ki > 4570 nM Bioactivity Info	TI LI LO TS
CP0472700 Compound Info	4-(2-(3-fluorophenoxy)-4-methylphenyl)piperidine Show/Hide	C18H20FNO	1
1	Ki > 4570 nM Bioactivity Info	TI LI LO TS
CP0156235 Compound Info	3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide Show/Hide	C18H30N2O2S	1
1	Ki > 7943 nM Bioactivity Info	TI LI LO TS
CP0404672 Compound Info	5-[2-[4-[(3,4-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C23H25Cl2N3O	1
1	Ki < 10000 nM Bioactivity Info	TI LI LO TS
CP0485418 Compound Info	5-[2-[4-[(2,6-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline Show/Hide	C23H25Cl2N3O	1
1	Ki < 10000 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000049 , C6

Cell Line Info

Cell Line ID: CL000026 , CHO-K1

Cell Line Info

Cell Line ID: CL000109 , COS-1

Cell Line Info

Cell Line ID: CL000053 , COS-7

Cell Line Info

Cell Line ID: CL000803 , HA7

Cell Line Info

Cell Line ID: CL000025 , HEK-293T

Cell Line Info

Cell Line ID: CL000006 , HEK293

Cell Line Info

Cell Line ID: CL000065 , HEK293-EBNA

Cell Line Info

Cell Line ID: CL000017 , HeLa

Cell Line Info

Cell Line ID: CL000101 , L-M(TK-)

Cell Line Info

Cell Line ID: CL000043 , U2OS

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0036542 Compound Info	(phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate Show/Hide	C25H29N3O2	2
1	Activity = 10 nM
2	Ki = 13 nM
CP0042927 Compound Info	7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one Show/Hide	C23H27Cl2N3O2	5
1	EC50 = 285 nM
2	Ki = 5.6 nM
3	Ki = 10 nM
4	Ki = 18 nM
5	Ki = 19.8 nM
CP0039958 Compound Info	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one Show/Hide	C23H27FN4O2	9
1	EC50 > 10000 nM
2	Kd = 398.11 nM
3	Ki = 21 nM
4	Ki = 182 nM
5	Ki = 190 nM
6	Ki = 210 nM
7	Ki = 253 nM
8	Ki = 271 nM
9	Ki = 1000 nM
CP0024732 Compound Info	5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide Show/Hide	C26H27N5O2	2
1	IC50 = 0.11 nM
2	Ki = 0.3 nM
CP0037227 Compound Info	7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol Show/Hide	C16H25NO	24
1	IC50 = 0.28 nM
2	IC50 = 0.33 nM
3	IC50 = 0.51 nM
4	IC50 = 0.59 nM
5	IC50 = 0.66 nM
6	IC50 = 1.1 nM
7	Ki = 0.17 nM
8	Ki = 0.18 nM
9	Ki = 0.21 nM
10	Ki = 0.66 nM
11	Ki = 0.7943 nM
12	Ki = 0.8 nM
13	Ki = 0.83 nM
14	Ki = 1 nM
15	Ki = 1.2 nM
16	Ki = 1.259 nM
17	Ki = 1.49 nM
18	Ki = 1.9 nM
19	Ki = 3.388 nM
20	Ki = 3.44 nM
21	Ki = 3.467 nM
22	Ki = 3.8 nM
23	Ki = 5 nM
24	Ki = 3981.07 nM
CP0001238 Compound Info	14C-5-hydroxy tryptamine creatinine disulfate Show/Hide	C10H12N2O	6
1	IC50 = 1.2 nM
2	IC50 = 5.2 nM
3	Ki = 1.259 nM
4	Ki = 2.48 nM
5	Ki = 2.5 nM
6	Ki = 10000 nM
CP0780574 Compound Info	N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide tri hydrochloride Show/Hide	C25H35ClN4O2	1
1	IC50 = 2.1 nM
CP0209946 Compound Info	Sarizotan Show/Hide	C22H21FN2O	1
1	IC50 < 6 nM
CP0057346 Compound Info	3-(2-aminopropyl)-1H-indol-5-ol Show/Hide	C11H14N2O	2
1	IC50 = 19.6 nM
2	Ki = 12 nM
CP0042717 Compound Info	(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione Show/Hide	C21H31N5O2	8
1	IC50 = 25 nM
2	Kd = 10 nM
3	Ki = 4 nM
4	Ki = 4.78 nM
5	Ki = 15 nM
6	Ki = 17 nM
7	Ki = 24 nM
8	Ki = 34.3 nM
CP0099665 Compound Info	2-(5-Methoxy-1H-indol-3-yl)-1-methyl-ethylamine Show/Hide	C12H16N2O	2
1	IC50 = 86.4 nM
2	Ki = 4.6 nM
CP0234687 Compound Info	4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione Show/Hide	C19H29N5O2	3
1	IC50 = 114 nM
2	Kd = 79.43 nM
3	Ki = 31.8 nM
CP0057042 Compound Info	(R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Show/Hide	C11H16INO2	2
1	IC50 = 3843 nM
2	Ki = 0.65 nM
CP0103855 Compound Info	1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine Show/Hide	C14H18N2O	1
1	IC50 = 10900 nM
CP0163540 Compound Info	1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine Show/Hide	C15H20N2O	2
1	IC50 = 12200 nM
2	Ki = 28 nM
CP0053464 Compound Info	3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)butyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one Show/Hide	C25H32N6O	2
1	IC50 > 1.358 nM
2	Ki = 0.7008 nM
CP0306958 Compound Info	(3aR,9bS) 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol Show/Hide	C15H21NO	2
1	Kd = 0.1 nM
2	Ki = 0.1 nM
CP0037866 Compound Info	CAS_146714-97-8 Show/Hide	C25H34N4O2	4
1	Kd = 0.2 nM
2	Ki = 0.1585 nM
3	Ki = 0.7943 nM
4	Ki = 2.2 nM
CP0099712 Compound Info	3-(2-aminoethyl)-1H-indole-5-carboxamide Show/Hide	C11H13N3O	2
1	Kd = 0.3981 nM
2	Ki < 0.3 nM
CP0037692 Compound Info	CAS_133025-23-7 Show/Hide	C24H33N3O2	1
1	Kd = 1.259 nM
CP0069764 Compound Info	7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide Show/Hide	C16H25NO	1
1	Kd = 1.995 nM
CP0059583 Compound Info	1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda6-benzo[d]isothiazol-3-one Show/Hide	C19H23N5O3S	1
1	Kd = 3.981 nM
CP0040671 Compound Info	8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one Show/Hide	C23H26FN3O2	1
1	Kd = 39.81 nM
CP0036702 Compound Info	1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol Show/Hide	C14H20N2O2	3
1	Kd = 63.1 nM
2	Ki = 22.4 nM
3	Ki = 110 nM
CP0285377 Compound Info	(3aS,9bR)-6-methoxy-3-prop-2-enyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indole Show/Hide	C16H21NO	1
1	Kd = 316.23 nM
CP0005653 Compound Info	(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide Show/Hide	C14H21N3O2S	5
1	Kd = 398.11 nM
2	Ki = 230 nM
3	Ki = 330 nM
4	Ki = 407.1 nM
5	Ki = 440 nM
CP0045063 Compound Info	2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine Show/Hide	C17H20N4S	6
1	Kd = 1258.93 nM
2	Ki = 610 nM
3	Ki = 2100 nM
4	Ki = 2720 nM
5	Ki = 7100 nM
6	Ki > 1000 nM
CP0479975 Compound Info	(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[[5-methyl-6-(methylamino)pyridin-2-yl]methylamino]methyl]piperidin-1-yl]methanone Show/Hide	C21H25ClF2N4O	1
1	Ki = 0.04 nM
CP0085342 Compound Info	2-[4-[4-[2-(2-fluoroethoxy)phenyl]piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C20H28FN5O3	1
1	Ki = 0.1 nM
CP0067876 Compound Info	CAS_0 Show/Hide	C19H27N5O3	1
1	Ki = 0.15 nM
CP0053378 Compound Info	2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione Show/Hide	C19H27N5O3	2
1	Ki = 0.15 nM
2	Ki = 1.1 nM
CP0067872 Compound Info	2-[4-[4-(6-fluoropyridin-2-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C17H23FN6O2	1
1	Ki = 0.2 nM
CP0152118 Compound Info	6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one Show/Hide	C26H29N3O3	2
1	Ki = 0.3162 nM
2	Ki = 2.512 nM
CP0061623 Compound Info	8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione Show/Hide	C22H31N3O3	4
1	Ki = 0.46 nM
2	Ki = 0.8 nM
3	Ki = 0.9333 nM
4	Ki = 1.259 nM
CP0699181 Compound Info	N-{2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl}-N-(2-pyridinyl)cyclohexane carboxamide trihydrochloride Show/Hide	C25H37Cl3N4O2	1
1	Ki = 0.6 nM
CP0085020 Compound Info	N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-N-pyridin-2-ylcyclohexanecarboxamide Show/Hide	C25H31N3O	1
1	Ki = 0.69 nM
CP0087672 Compound Info	(1R,2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]-5-fluoro-2,3-dihydro-1H-inden-1-ol Show/Hide	C22H22FNO3	1
1	Ki = 0.8511 nM
CP0071669 Compound Info	(3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-methanone Show/Hide	C20H22ClF2N3O	1
1	Ki = 1 nM
CP0045725 Compound Info	(4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide Show/Hide	C20H25N3O	1
1	Ki = 1.1 nM
CP0067873 Compound Info	4-methyl-2-[4-(4-pyridin-2-ylpiperazin-1-yl)butyl]-1,2,4-triazine-3,5-dione Show/Hide	C17H24N6O2	1
1	Ki = 1.1 nM
CP0268138 Compound Info	2-[4-[4-(3-fluoropyridin-2-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C17H23FN6O2	1
1	Ki = 1.2 nM
CP0037362 Compound Info	((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium Show/Hide	C16H25NO	1
1	Ki = 1.3 nM
CP0192158 Compound Info	(S)-1-(1H-indol-4-yloxy)-3-(cyclohexylamino)propan-2-ol Show/Hide	C17H24N2O2	1
1	Ki = 1.33 nM
CP0199294 Compound Info	N-[2-[4-(2-hydroxyphenyl)piperazin-1-yl]ethyl]-4-iodo-N-pyridin-2-ylcubane-1-carboxamide Show/Hide	C26H27IN4O2	1
1	Ki = 1.4 nM
CP0129126 Compound Info	2-[4-[4-(6-bromopyridin-2-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C17H23BrN6O2	1
1	Ki = 1.4 nM
CP0425851 Compound Info	N-[2-[4-(2-hydroxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide Show/Hide	C24H32N4O2	1
1	Ki = 1.4 nM
CP0076345 Compound Info	5-Acetyl-4-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propylamino}-2,6-dimethyl-2H-pyridazin-3-one Show/Hide	C22H31N5O3	1
1	Ki = 1.48 nM
CP0234879 Compound Info	2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methyl)phenyl)methoxy)-1H-indol-3-yl)ethanamine Show/Hide	C28H30N4O2	1
1	Ki = 1.6 nM
CP0100452 Compound Info	(R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C23H21N	1
1	Ki = 1.8 nM
CP0139060 Compound Info	N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-pyridin-2-ylcyclohexanecarboxamide Show/Hide	C24H32N4O	1
1	Ki = 1.85 nM
CP0192883 Compound Info	(3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide Show/Hide	C16H22N2O	1
1	Ki = 1.9 nM
CP0082953 Compound Info	2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride Show/Hide	C19H23NO5	1
1	Ki = 2.089 nM
CP0199295 Compound Info	4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cubyl-1-carboxamide Show/Hide	C27H29IN4O2	1
1	Ki = 2.2 nM
CP0056386 Compound Info	5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one Show/Hide	C21H21ClN4OS	3
1	Ki = 2.5 nM
2	Ki = 4 nM
3	Ki = 37 nM
CP0418985 Compound Info	4-methyl-2-[4-(4-phenylpiperazin-1-yl)butyl]-1,2,4-triazine-3,5-dione Show/Hide	C18H25N5O2	1
1	Ki = 2.5 nM
CP0173138 Compound Info	N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]methanesulfonamide Show/Hide	C25H31N3O3S	1
1	Ki = 2.512 nM
CP0118796 Compound Info	Cariprazine Show/Hide	C21H32Cl2N4O	1
1	Ki = 3.1 nM
CP0224658 Compound Info	8-chloro-7-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butoxy]-4-methylchromen-2-one Show/Hide	C26H26ClFN2O4	1
1	Ki = 3.3 nM
CP0144434 Compound Info	1-(1H-indol-4-yloxy)-3-(cyclohexylamino)propan-2-ol Show/Hide	C17H24N2O2	1
1	Ki = 3.58 nM
CP0059105 Compound Info	(S)-1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-propan-2-ol Show/Hide	C21H28N2O2	1
1	Ki = 3.89 nM
CP0077913 Compound Info	5-chloro-6-(4-methylpiperazin-1-yl)-N-(4-pyridin-4-ylnaphthalen-1-yl)-2,3-dihydroindole-1-carboxamide Show/Hide	C29H28ClN5O	2
1	Ki = 3.981 nM
2	Ki = 10 nM
CP0157934 Compound Info	2-[(1S)-1-[2-(cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole Show/Hide	C15H20N2O	1
1	Ki = 5.754 nM
CP0025667 Compound Info	2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone Show/Hide	C18H19ClN4	8
1	Ki = 6.38 nM
2	Ki = 8.9 nM
3	Ki = 140 nM
4	Ki = 160 nM
5	Ki = 270 nM
6	Ki = 416.87 nM
7	Ki = 710 nM
8	Ki = 1000 nM
CP0187051 Compound Info	1-(1H-indol-4-yloxy)-3-(cycloheptylamino)propan-2-ol Show/Hide	C18H26N2O2	1
1	Ki = 6.82 nM
CP0191791 Compound Info	(+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(1-cyclopropylethyl)pyrimidin-2-amine Show/Hide	C24H31N5	1
1	Ki = 7.4 nM
CP0102236 Compound Info	2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-tolyl-piperazin-1-yl)-ethanone Show/Hide	C23H28N4O2	2
1	Ki = 7.7 nM
2	Ki = 8 nM
CP0173454 Compound Info	1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]-1-yl-2-propanol Show/Hide	C26H29NO2	1
1	Ki = 8.3 nM
CP0218398 Compound Info	6-[5-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]pentanoyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one Show/Hide	C28H30FN3O3	1
1	Ki = 8.6 nM
CP0151604 Compound Info	2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphthalen-1-yl-piperazin-1-yl)-ethanone Show/Hide	C26H28N4O2	1
1	Ki = 8.9 nM
CP0061753 Compound Info	1-NP Show/Hide	C14H16N2	1
1	Ki = 9.23 nM
CP0203691 Compound Info	1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-propan-2-ol Show/Hide	C21H28N2O2	1
1	Ki = 9.29 nM
CP0059646 Compound Info	7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzooxazol-2-one Show/Hide	C24H23N3O2	1
1	Ki = 9.3 nM
CP0056131 Compound Info	2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-methoxy-phenyl)-piperazin-1-yl]-ethanone Show/Hide	C23H28N4O3	1
1	Ki = 9.8 nM
CP0162751 Compound Info	2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-phenyl-piperazin-1-yl)-ethanone Show/Hide	C22H26N4O2	2
1	Ki = 10.4 nM
2	Ki = 11.4 nM
CP0087650 Compound Info	2-[1-[2-(cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole Show/Hide	C15H20N2O	1
1	Ki = 10.47 nM
CP0144433 Compound Info	1-(1H-indol-4-yloxy)-3-(cyclopentylamino)propan-2-ol Show/Hide	C16H22N2O2	1
1	Ki = 10.6 nM
CP0144436 Compound Info	(S)-1-(adamantan-2-ylamino)-3-(1H-indol-4-yloxy)-propan-2-ol Show/Hide	C21H28N2O2	1
1	Ki = 11.2 nM
CP0658701 Compound Info	1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride Show/Hide	C18H23ClN2S	1
1	Ki = 15 nM
CP0394360 Compound Info	1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine Show/Hide	C18H22N2S	1
1	Ki = 15 nM
CP0288408 Compound Info	1-[(4,4-diphenyl-1,3-dioxolan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine Show/Hide	C27H30N2O3	1
1	Ki = 15.14 nM
CP0214664 Compound Info	2-(dimethylamino)-N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]acetamide Show/Hide	C28H36N4O2	1
1	Ki = 15.85 nM
CP0074213 Compound Info	2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-amine Show/Hide	C15H18N2S	1
1	Ki = 16 nM
CP0080064 Compound Info	(1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene Show/Hide	C20H21NO	1
1	Ki = 17.3 nM
CP0137379 Compound Info	4-Benzyl-1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidine Show/Hide	C21H25NO2	1
1	Ki = 17.6 nM
CP0144435 Compound Info	(R)-1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-propan-2-ol Show/Hide	C21H28N2O2	1
1	Ki = 18.3 nM
CP0194739 Compound Info	(+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(cyclopropylmethyl)pyrimidin-2-amine Show/Hide	C23H29N5	1
1	Ki = 21.3 nM
CP0062567 Compound Info	ALPRENOLOL,(+) Show/Hide	C15H23NO2	1
1	Ki = 21.6 nM
CP0371039 Compound Info	N-cyclopropyl-4-[1-[2-(5-fluoro-1H-indol-3-yl)ethyl]piperidin-3-yl]pyrimidin-2-amine Show/Hide	C22H26FN5	1
1	Ki = 23.6 nM
CP0715545 Compound Info	Tert-butyl (18-(2-allylphenoxy)-17-hydroxy-3,6,9,12-tetraoxa-15-azaoctadecyl)carbamate Show/Hide	C27H46N2O8	1
1	Ki = 24.1 nM
CP0732169 Compound Info	Methyl 2-((3-(2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)propyl)thio)acetate Show/Hide	C18H29NO4S	1
1	Ki = 24.1 nM
CP0059104 Compound Info	(R)-1-(1H-indol-4-yloxy)-3-(cyclohexylamino)propan-2-ol Show/Hide	C17H24N2O2	1
1	Ki = 26.1 nM
CP0183973 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C22H24F2N2O2	3
1	Ki = 26.6 nM
2	Ki = 27 nM
3	Ki = 30 nM
CP0157930 Compound Info	2-[1-(2-prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole Show/Hide	C14H18N2O	1
1	Ki = 28.18 nM
CP0187050 Compound Info	1-(1H-indol-4-yloxy)-3-(pentan-3-ylamino)propan-2-ol Show/Hide	C16H24N2O2	1
1	Ki = 28.6 nM
CP0354473 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C21H22F2N2O2	1
1	Ki = 30 nM
CP0127497 Compound Info	N-cyclopropyl-4-[1-[2-(7-fluoro-1H-indol-3-yl)ethyl]piperidin-3-yl]pyrimidin-2-amine Show/Hide	C22H26FN5	1
1	Ki = 35.1 nM
CP0157932 Compound Info	2-[(1S)-1-(2-prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole Show/Hide	C14H18N2O	1
1	Ki = 35.48 nM
CP0665629 Compound Info	Tert-butyl (15-(2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-10-oxo-3,6-dioxa-12-thia-9-azapentadecyl)carbamate Show/Hide	C28H49N3O7S	1
1	Ki = 35.8 nM
CP0700254 Compound Info	18-(2-allylphenoxy)-1-amino-3,6,9,12-tetraoxa-15-azaoctadecan-17-ol Show/Hide	C22H38N2O6	1
1	Ki = 35.8 nM
CP0087658 Compound Info	2-[(1R)-1-[2-(cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole Show/Hide	C15H20N2O	1
1	Ki = 39.81 nM
CP0106069 Compound Info	6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene Show/Hide	C18H17N	1
1	Ki = 40.7 nM
CP0068173 Compound Info	2-Aminopyrimidine analog., 4 Show/Hide	C16H18N6	1
1	Ki = 42 nM
CP0191793 Compound Info	N-cyclopropyl-4-[1-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]piperidin-3-yl]pyrimidin-2-amine Show/Hide	C23H30N4	1
1	Ki = 42.5 nM
CP0123042 Compound Info	2-[4-[4-(4-iodophenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione Show/Hide	C18H24IN5O2	1
1	Ki = 58.8 nM
CP0152465 Compound Info	4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(2-methoxyethyl)pyrimidin-2-amine Show/Hide	C22H29N5O	1
1	Ki = 66.3 nM
CP0048572 Compound Info	1-Benzyl-4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperazine Show/Hide	C20H24N2O2	1
1	Ki = 69.4 nM
CP0322305 Compound Info	(+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-cyclopropylpyrimidin-2-amine Show/Hide	C22H27N5	1
1	Ki = 75.3 nM
CP0144438 Compound Info	4-(adamantan-1-ylamino)-1-(1H-indol-4-yloxy)-butan-2-ol Show/Hide	C22H30N2O2	1
1	Ki = 76.1 nM
CP0275909 Compound Info	N-[4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]phenyl]acetamide Show/Hide	C24H29N5O3	1
1	Ki = 77.8 nM
CP0230830 Compound Info	4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(3-methoxypropyl)pyrimidin-2-amine Show/Hide	C23H31N5O	1
1	Ki = 78.3 nM
CP0044066 Compound Info	(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Show/Hide	C17H17N	1
1	Ki = 80 nM
CP0169088 Compound Info	(2S)-N,N-dimethyl-5-(1,3,5-trimethylpyrazol-4-yl)-1,2,3,4-tetrahydronaphthalen-2-amine Show/Hide	C18H25N3	1
1	Ki = 89.7 nM
CP0144432 Compound Info	N-[3-(1H-indol-4-yloxy)propyl]cyclopentanamine Show/Hide	C16H22N2O	1
1	Ki = 94.3 nM
CP0105569 Compound Info	N-[4-(4-phenylpiperazin-1-yl)butyl]quinoline-6-carboxamide Show/Hide	C24H28N4O	1
1	Ki = 99 nM
CP0259093 Compound Info	N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide Show/Hide	C24H29N3O3S	1
1	Ki = 112 nM
CP0309095 Compound Info	1-(1H-indol-4-yloxy)-4-(cyclohexylamino)butan-2-ol Show/Hide	C18H26N2O2	1
1	Ki = 125 nM
CP0168742 Compound Info	2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-2a,3,4,5-tetrahydrobenzo[cd]indol-2(1H)-one Show/Hide	C26H30N2O	1
1	Ki = 169 nM
CP0158311 Compound Info	3-(4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)pyrimidin-2-ylamino)propan-1-ol Show/Hide	C22H29N5O	1
1	Ki = 175 nM
CP0040250 Compound Info	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol Show/Hide	C21H25N3O2S	4
1	Ki = 180 nM
2	Ki = 230 nM
3	Ki = 830 nM
4	Ki = 1000 nM
CP0142787 Compound Info	2-[3-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]propyl]-1,3-benzothiazole Show/Hide	C21H24ClN3S	1
1	Ki = 216 nM
CP0692947 Compound Info	21-(2-allylphenoxy)-20-hydroxy-2-oxo-6,9,12,15-tetraoxa-3,18-diazahenicosane-1-sulfonic acid Show/Hide	C24H40N2O10S	1
1	Ki = 261 nM
CP0715546 Compound Info	3-(2-((1E,3E)-5-((E)-3,3-Dimethyl-5-sulfo-1-(3-sulfopropyl)indolin-2-ylidene)penta-1,3-dien-1-yl)-3-(1-(2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-6,17-dioxo-10,13-dioxa-4-thia-7,16-diazadocosan-22-yl)-3-methyl-5-sulfo-3H-indol-1-ium-1-yl)propane-1-sulfonate Show/Hide	C59H85N5O18S5	1
1	Ki = 261 nM
CP0077356 Compound Info	2-[4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]butyl]-1,3-benzothiazole Show/Hide	C22H26ClN3S	1
1	Ki = 263 nM
CP0233824 Compound Info	4-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide Show/Hide	C21H29N3O4S	1
1	Ki = 272 nM
CP0042751 Compound Info	(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride Show/Hide	C17H17NO2	1
1	Ki = 296 nM
CP0072419 Compound Info	(SNAP-8719)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone Show/Hide	C22H28F3N3O2	1
1	Ki = 300 nM
CP0079263 Compound Info	2-methyl-5-[2-[4-(quinolin-8-ylmethyl)piperazin-1-yl]ethoxy]quinoline Show/Hide	C26H28N4O	1
1	Ki = 316.23 nM
CP0041243 Compound Info	5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride Show/Hide	C20H22ClN3O3S2	1
1	Ki = 340 nM
CP0062900 Compound Info	(1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine Show/Hide	C18H18N2	1
1	Ki = 355 nM
CP0070944 Compound Info	N-[(4-cyanophenyl)methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide Show/Hide	C30H34N4O	1
1	Ki = 379 nM
CP0056709 Compound Info	4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethylamino}-2-methyl-6-phenyl-5-propionyl-2H-pyridazin-3-one Show/Hide	C27H33N5O3	1
1	Ki = 406 nM
CP0166862 Compound Info	1-(1,3-benzothiazol-2-yl)-5-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]pentan-1-one Show/Hide	C23H26ClN3OS	1
1	Ki = 495 nM
CP0037955 Compound Info	METHIOTHEPIN Show/Hide	C20H24N2S2	1
1	Ki = 630.96 nM
CP0045069 Compound Info	2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N,N-dimethylethanamine Show/Hide	C19H22N2O3S	1
1	Ki = 702 nM
CP0182705 Compound Info	(R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt) Show/Hide	C19H30N2O2S	1
1	Ki = 1000 nM
CP0834374 Compound Info	4-((15-(2-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)-10-oxo-3,6-dioxa-12-thia-9-azapentadecyl)carbamoyl)cyclobutane-1,2,3-tricarboxylic acid Show/Hide	C31H47N3O12S	1
1	Ki = 1720 nM
CP0665628 Compound Info	4-((18-(2-allylphenoxy)-17-hydroxy-3,6,9,12-tetraoxa-15-azaoctadecyl)carbamoyl)cyclobutane-1,2,3-tricarboxylic acid Show/Hide	C30H44N2O13	1
1	Ki = 1780 nM
CP0707834 Compound Info	18-(2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-2,13-dioxo-6,9-dioxa-15-thia-3,12-diazaoctadecane-1-sulfonic acid Show/Hide	C25H43N3O9S2	1
1	Ki = 1780 nM
CP0008601 Compound Info	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl) Show/Hide	C21H23ClFNO2	2
1	Ki = 2800 nM
2	Ki = 3600 nM
CP0665630 Compound Info	N-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-2-((3-(2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)propyl)thio)acetamide Show/Hide	C23H41N3O5S	1
1	Ki = 2860 nM
CP0700117 Compound Info	3-(3-(1-(2-Allylphenoxy)-2-hydroxy-20-oxo-7,10,13,16-tetraoxa-4,19-diazapentacosan-25-yl)-2-((1E,3E)-5-((E)-3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)indolin-2-ylidene)penta-1,3-dien-1-yl)-3-methyl-5-sulfo-3H-indol-1-ium-1-yl)propane-1-sulfonate Show/Hide	C58H82N4O19S4	1
1	Ki = 2860 nM
CP0122652 Compound Info	3-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione Show/Hide	C30H33FN4O3	1
1	Ki = 5570 nM
CP0040814 Compound Info	[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone Show/Hide	C19H21N5O4	1
1	Ki > 10 nM
CP0052721 Compound Info	1-[(E)-6-(3,4-dihydro-1H-isoquinolin-2-yl)hex-3-enyl]-3H-indol-2-one Show/Hide	C23H26N2O	1
1	Ki > 1000 nM
CP0156235 Compound Info	3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide Show/Hide	C18H30N2O2S	1
1	Ki > 3000 nM
CP0096286 Compound Info	(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol Show/Hide	C18H28N2O3S	1
1	Ki > 10000 nM

Clinical Information about the Protein

Target 1 ( 5-HT 1A receptor (HTR1A) )

Target Type	Successful Target
Disease	15 Target-related Diseases				15
1	Anxiety disorder [ICD-11: 6B00-6B0Z]
2	Mood disorder [ICD-11: 6A60-6E23]
3	Major depressive disorder [ICD-11: 6A70.3]
4	Hypertension [ICD-11: BA00-BA04]
5	Depression [ICD-11: 6A70-6A7Z]
6	Attention deficit hyperactivity disorder [ICD-11: 6A05.Z]
7	Coronary artery disease [ICD-11: BA80]
8	Psychotic disorder [ICD-11: 6A20-6A25]
9	Rett syndrome [ICD-11: LD90.4]
10	Schizophrenia [ICD-11: 6A20]
11	Addictive disorder [ICD-11: 6C50-6C5Z]
12	Juvenile idiopathic arthritis [ICD-11: FA24]
13	Urinary incontinence [ICD-11: MF50.2]
14	Pain [ICD-11: MG30-MG3Z]
15	Eating disorder [ICD-11: 6B82]
Approved Drug(s)	8 Approved Drugs				8
1	Buspirone	Drug Info	Approved	Anxiety disorder
2	Flibanserin	Drug Info	Approved	Mood disorder
3	OPC-34712	Drug Info	Approved	Major depressive disorder
4	TERTATOLOL	Drug Info	Approved	Hypertension
5	Trazodone	Drug Info	Approved	Depression
6	Urapidil	Drug Info	Approved	Hypertension
7	Vilazodone	Drug Info	Approved	Major depressive disorder
8	Gepirone	Drug Info	Approved	Major depressive disorder
Clinical Trial Drug(s)	10 Clinical Trial Drugs				10
1	Eltoprazine	Drug Info	Phase 3	Attention deficit hyperactivity disorder
2	OPC-14523	Drug Info	Phase 2	Mood disorder
3	S-15535	Drug Info	Phase 2	Anxiety disorder
4	SUN N4057	Drug Info	Phase 2	Coronary artery disease
5	1192U90	Drug Info	Phase 1	Psychotic disorder
6	DSP-1053	Drug Info	Phase 1	Major depressive disorder
7	NLX-101	Drug Info	Phase 1	Rett syndrome
8	SEP-363856	Drug Info	Phase 3	Schizophrenia
9	Xaliproden	Drug Info	Phase 3	Juvenile idiopathic arthritis
10	Sarizotan	Drug Info	Phase 2/3	Rett syndrome
Discontinued Drug(s)	18 Discontinued Drugs				18
1	LYSERGIC ACID DIETHYLAMIDE	Drug Info	Withdrawn from market	Addictive disorder
2	Bifeprunox	Drug Info	Discontinued in Phase 3	Schizophrenia
3	BMS-181100	Drug Info	Discontinued in Phase 3	Psychotic disorder
4	Flesinoxan	Drug Info	Discontinued in Phase 3	Anxiety disorder
5	DU 125530	Drug Info	Discontinued in Phase 2	Mood disorder
6	GSK163090	Drug Info	Discontinued in Phase 2	Anxiety disorder
7	PRX-00023	Drug Info	Discontinued in Phase 2	Mood disorder
8	REC-15/3079	Drug Info	Discontinued in Phase 2	Urinary incontinence
9	DU-29894	Drug Info	Discontinued in Phase 1	Psychotic disorder
10	Ebalzotan	Drug Info	Discontinued in Phase 1	Anxiety disorder
11	Eptapirone	Drug Info	Discontinued in Phase 1	Anxiety disorder
12	SLV-313	Drug Info	Discontinued in Phase 1	Schizophrenia
13	U-93385	Drug Info	Discontinued in Phase 1	Anxiety disorder
14	Anpirtoline	Drug Info	Terminated	Pain
15	Ipsapirone	Drug Info	Terminated	Anxiety disorder
16	RWJ-25730	Drug Info	Terminated	Psychotic disorder
17	S-14506	Drug Info	Terminated	Anxiety disorder
18	WAY-100635	Drug Info	Terminated	Eating disorder

Similar Protein(s) and Bioactivity Statistics

50% Identity

Protein ID	Protein Name	Protein Organism
PT01448	5-hydroxytryptamine receptor 1A	Rattus norvegicus, Rat	Protein Info
PT01723	5-hydroxytryptamine receptor 1A	Mus musculus, Mouse	Protein Info

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han